The disruptive personalized machine-based genetic counseling platform

Descrizione del progetto

Consulente intelligente per la medicina personalizzata basata sulla genetica

Il trattamento personalizzato basato su dati genetici è il futuro della medicina. Tuttavia, sono noti solo 7 000 consulenti genetici professionali in tutto il mondo in grado di guidare i pazienti attraverso decisioni pertinenti. La soluzione più accurata è la consulenza genetica (GC) automatizzata. Il progetto Igentify, finanziato dall’UE, mira a sviluppare il primo «Digital Genetic Counselor» (consulente genetico digitale) al mondo, una piattaforma digitale per i fornitori di test genetici. Essa offrirà una soluzione di consulenza completamente scalabile per applicazioni di test genetici sia clinici che non clinici. Applicherà inoltre varie tecnologie di genotipizzazione come un microarray e il sequenziamento di nuova generazione (NGS). Grazie ad algoritmi che analizzano tutti i parametri relativi alla genetica, la soluzione elabora automaticamente il profilo individuale di un paziente. L’innovativo algoritmo di generazione di risorse audiovisive consente contenuti educativi per ogni paziente.

Obiettivo

The promise of personalized medicine will soon materialize. However, this revolution will require genetic counsellors as key professional to facilitate patients´ informed decision-making. However, there are just 7,000 worldwide, insufficient to fulfil the ever-growing demand for these services (>40 million people tested in 2018). Likewise, health care organizations cannot implement genetic counselling (GC) as a tool to help patients understand, adapt and adjust to the medical and psychological consequences of their genetic tests results. Innovative automated solutions are needed to fully exploit the benefits from the upcoming genomic revolution to overcome, not just the shortage but also expensive, time consuming and not scalable current GC approach.
At Igentify Ltd, an Israeli startup home to 32 highly-skilled individuals, we have created the first clinically-approved Igentify: A 4 module-based machine learning digital platform automating all stages from the GC process, starting from enrolment of the patient into the system, until the delivery of customized machine generated GC. Igentify incorporates 2 features simplifying and making scalable GC: (1) A set of algorithms analysing all genetic-related parameters (e.g. ethnicity, carrier frequency, medical history, lifestyle, etc.) to profile the individual as low or high-risk. (2) A revolutionary audio-visual asset generation algorithm that autonomously creates dynamic audio-visual content customized for patients, explaining all information in an educational way. We have commercial agreements with early adopters, including Northwell Health, Gene by Gene, Kaplan Medical Center or Meudehet, confirming Igentify´s business opportunity.
We expect to gain a 4% market share within the global genetic testing market (€16.7 billion valuation by 2024, CAGR of 12.2%, period 2018-2024). This will translate into a revenue of € 104.06 M in 2026 (ROI of 7.04) while creating 150 jobs.