Organ shortage is the greatest challenge in the field of organ transplantation. In Europe, 18 persons die every day waiting for transplants and a new patient is added to the waiting list every 10 minutes. Yet each year, a great many organs are wasted because of logistical constraints that could be overcome by organ preservation advances. After removal, organs can only be kept alive for a short period of time (<24h) and insufficient preservation places important logistical limitations. Organs cannot travel long distances severely limiting global transplantation access. Medical staff have only little room to adapt procedures to circumstances or deal with complications with poor outcome to patients. And there is an important cost due to fast delivery and on-the-call surgery reaching as high as €115 000 per patient. To address this challenge ElaPharma has come with a new solution: A small additive molecules inhibiting an intracellular enzyme involved in organ necrosis during preservation. Intended for flushing organs at the time of removal from the donor for storage and transportation, ElaPharma successfully maintain some implants organs (lung and skin) for more than 24h, suppressing all supply constraints to organ replacement. After confirming its technical and commercial feasibility, ElaPharma will reach market thanks to EIC Accelerator by: 1) Optimizing molecule for organ preservation; 2) Elaborating molecule formulation; 3) Processing to pre-clinical and; 4) clinical validation; 5) commercializing the product by a comprehensive dissemination-communication. We will use a B2B strategy with a joint venture with an important company to scale up it expansion. Market launch is expected for 2023, with €83.1M revenue accumulated by 2027 while contributing to increasing organs availability, saving lives to people in need of transplantation.
