The research activity of READESCARTES concerns commentaries and lectures or university dictata (in handwritten and printed form) by authors directly inspired by Cartesian thought, esp. Johannes de Raey and Johannes Clauberg, and related authors like Henricus Regius, Christopher Wittich, Burchard de Volder, and Johannes Swammerdam, as well as related sources like treatises, research papers, correspondences, and disputations. First (months 1–3), it is conducted an assessment and localization of handwritten commentaries and lectures on Cartesian treatises, by an integration of intellectual-historical and archival methodologies, namely by (1) a consultation the testaments and the auction catalogues of professors, students and book collectors, (2) a systematic survey on the references to Cartesian commentaries in printed books, in their different editions, and (3) a consultation of library and archive catalogues. Hence (months 4–12), a selection of handwritten primary sources is transcribed and critically edited, and their structure and textual agreements with each other and with printed sources is mapped with the crucial help of digital means, combining (1) a standard philological approach with (2) techniques in the digital humanities, viz. the use of optical text recognition softwares and sources (Adobe, Google, Transkribus) and by a flexible re-use of anti-plagiarism softwares (compilatio.net Turnitin). Eventually (months 13–24) it is analysed how Cartesian thought was interpreted and how this generated new knowledge, by assessing (1) the foremost issues dealt with in Cartesian commentaries: in particular, the discussion of the ideas of motion, place, and space; (2) the new views commentaries offered: in particular, the developments of the idea of force in Cartesian-inspired natural philosophies. Finally, the project assesses (3) the relations between commentaries and printed texts: this shows how Cartesian commentaries offered a much richer discussion of such issue than printed texts, and demonstrates the crucial role of handwritten sources – in particular, didactic ones – in the genesis of knowledge in the seventeenth century. The research results of READESCARTES are disseminated by 5 conference talks, 4 workshops, and by a series of 14 talks organized by the PI; moreover, by a monograph, 7 research articles, one collective volume edited by the PI, and one popularising article.