Precisely Patterned Nanofibers for High Performance Bioseparations

Project Information

PURE

Grant agreement ID: 899732

DOI 10.3030/899732

EC signature date 26 May 2020

Start date 1 October 2020

End date 30 September 2024

Funded under

• EXCELLENT SCIENCE - Future and Emerging Technologies (FET)

Total cost € 2 999 537,50

EU contribution € 2 999 537,50

Coordinated by

UNIVERSIDADE NOVA DE LISBOA
Portugal

Deliverables

Other (3)

Bioproduction of non-canonical amino acids

At least 500 mg of reactive ncAA AhA will be produced by biotechnological means

Bioproduction of unmodified spidroins

At least 500 mg of unmodified spidroins will be biologically produced

Production of activated affinity ligands

At least 250 mg of each activated affinity ligand will be attained The affinity ligands selective for factor VIII Mabs VLPs and protein A will be produced and modified with DBCO for further modification of labeled spidroin

Open Research Data Pilot (1)

Data Management Plan

Data Management PlanA detailed Data Management Plan will be created at the beginning of the project to ensure that all data is findable accessible interoperable and reusable FAIR The plan will be harmonized with a knowledge protection plan IPR plan

Documents, reports (1)

Dissemination and Exploitation Plan

Dissemination and Exploitation Plan at the end of the first Reporting Period RP1 M12

Websites, patent fillings, videos etc. (1)

PURE webportal operational

Publications

Thesis and dissertations (3)

Immobilization of antibodies on non-wovens made of recombinant spyder silk proteins

Author(s): Charlotte Leonhardt
Published in: 2021
Publisher: Universitat Bayreuth

Production of non-woven meshes based on modified eADF4(Ω16) spider silk proteins for the immobilization of antibodies

Author(s): Amelie Linder
Published in: 2022
Publisher: Universitat Bayreuth

Sustainable fibers for bioseparation: innovation, market transfer and a collaborative model

Author(s): José Pedro Fradique Lourenço Dias Dinis
Published in: 2022
Publisher: Universidade NOVA de Lisboa

Peer reviewed articles (1)

Native, engineered and de novo designed ligands targeting the SARS-CoV-2 spike protein

Author(s): Costa, Carlos Filipe Santos; Barbosa, Arménio J. M.; Dias, Ana Margarida Gonçalves Carvalho; Roque, Ana Cecília A.
Published in: Biotechnology Advances, Issue 59, 2022, Page(s) 107986, ISSN 0734-9750
Publisher: Elsevier BV
DOI: 10.1016/j.biotechadv.2022.107986