Descripción del proyecto
Una solución innovadora para el tratamiento de pacientes de edad avanzada con cáncer de mama en riesgo de cardiotoxicidad
Los factores relacionados con la edad y la comorbilidad aumentan la vulnerabilidad de los pacientes con cáncer de mama a la cardiotoxicidad durante el tratamiento del cáncer. La falta de mejores prácticas y el sesgo de fragilidad en estos pacientes, subrepresentados en los ensayos, pueden conducir a intervenciones inadecuadas y a un tratamiento insuficiente, y dar lugar así a un deterioro de la calidad de vida, peores resultados y unos costes mayores de la atención sanitaria. El proyecto financiado con fondos europeos CARDIOCARE se centrará en la población de edad avanzada con cáncer de mama. Mediante un enfoque holístico que incluye aplicaciones de sanidad electrónica, sensores ponibles y biomarcadores, permitirá a los pacientes participar en su proceso asistencial y mejorar su salud física y mental, lo que contribuirá a su plan de atención individualizado y a una adaptación psicológica a su enfermedad. CARDIOCARE permitirá una estratificación efectiva del riesgo, lo que mitigará la cardiotoxicidad y los efectos adversos, minimizará la hospitalización y mejorará la calidad de vida.
Objetivo
More than 50% of the newly diagnosed breast cancer patients are elderly and particularly susceptible to cardiotoxicity of cancer treatment due to age-related factors and prevalence of multiple co-morbidities. The cumulative effect of risk factors in the elderly patient resembles a “snowball effect”, where baseline age and cancer-related changes are exacerbated by direct therapy-induced cardiotoxicity, resulting to a multi-morbid state and mortality. Frailty and high risk of cardiotoxicity in this group may lead to inappropriate interventions and undertreatment, resulting in poorer outcomes, deterioration of QoL and increased healthcare costs. Considering, that older cancer patients are underrepresented in trials, new interdisciplinary and patient-oriented studies able to provide clinical guidelines and best practices for delivering quality care are needed.
CARDIOCARE will contribute to scale up a better management for the multimorbid elderly breast cancer patients. Innovative eHealth applications, coupled with sensors and wearables, will permit a consistent evaluation of the intrinsic capacity and by combining clinical and biological features, will provide a holistic approach to the management of cancer and his co-morbidities in the elderly population. This will allow the development of quality indicators for effective care pathways and allow a more informed approach to breast cancer patients with multimorbidity, training and education of caregivers and stakeholders to boost effectively elderly breast cancer patients along disease trajectory and cardiotoxicity. eHealth applications will increase the involvement and participation of the patients in their care process and self-management improving adherence to their individualized care plan, and a better psychological adaptation to their disease. Overall, the implementation of a comprehensive model for effective risk stratification will positively impact on QoL, adverse events, hospitalizations, and healthcare.
Ámbito científico
- medical and health scienceshealth scienceshealth care serviceseHealth
- social sciencessociologydemographymortality
- medical and health sciencesclinical medicineoncologybreast cancer
- engineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensors
Palabras clave
Programa(s)
Tema(s)
Convocatoria de propuestas
Consulte otros proyectos de esta convocatoriaConvocatoria de subcontratación
H2020-SC1-2020-Two-Stage-RTD
Régimen de financiación
RIA - Research and Innovation actionCoordinador
45110 Ioannina
Grecia