Unraveling the complexity of fungal drug tolerance at multiple scales of biology

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Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Publications

The natural diversity of the yeast proteome reveals chromosome-wide dosage compensation in aneuploids

Auteurs: Julia Muenzner, Pauline Trébulle, Federica Agostini, Christoph B. Messner, Martin Steger, Andrea Lehmann, Elodie Caudal, Anna-Sophia Egger, Fatma Amari, Natalie Barthel, Matteo De Chiara, Michael Mülleder, Vadim Demichev, Gianni Liti, Joseph Schacherer, Toni Gossmann, Judith Berman, Markus Ralser
Publié dans: bioRxiv -, 2022
Éditeur: Biorxiv
DOI: 10.1101/2022.04.06.487392

Inorganic sulfur fixation via a new homocysteine synthase allows yeast cells to cooperatively compensate for methionine auxotrophy

Auteurs: Jason S.L. Yu, Benjamin M. Heineike, Johannes Hartl, Clara Correia-Melo, Simran Kaur Aulakh, Andrea Lehmann, Oliver Lemke, Federica Agostini, Cory T. Lee, Vadim Demichev, Christoph B. Messner, Michael Mülleder, Markus Ralser
Publié dans: bioRxiv -, 2022
Éditeur: Biorxiv
DOI: 10.1101/2022.03.14.484209

The Proteomic Landscape of Genome-Wide Genetic Perturbations

Auteurs: Christoph B. Messner, Vadim Demichev, Julia Muenzner, Simran Aulakh, Annika Röhl, Lucía Herrera-Domínguez, Anna-Sophia Egger, Stephan Kamrad, Oliver Lemke, Enrica Calvani, Michael Mülleder, Kathryn S. Lilley, Georg Kustatscher, Markus Ralser
Publié dans: bioRxiv -, 2022
Éditeur: Biorxiv
DOI: 10.1101/2022.05.17.492318

High-throughput proteomics of nanogram-scale samples with Zeno SWATH DIA

Auteurs: Ziyue Wang, Michael Mülleder, Ihor Batruch, Anjali Chelur, Kathrin Textoris-Taube, Torsten Schwecke, Johannes Hartl, Jason Causon, Jose Castro-Perez, Vadim Demichev, Stephen Tate, Markus Ralser
Publié dans: bioRxiv -, 2022
Éditeur: Biorxiv
DOI: 10.1101/2022.04.14.488299

Species-wide quantitative transcriptomes and proteomes reveal distinct genetic control of gene expression variation in yeast

Auteurs: E. Teyssonnière, P. Trébulle, J. Muenzner, V. Loegler, D. Ludwig, F. Amari, M. Mülleder, A. Friedrich, J. Hou, M. Ralser, J. Schacherer
Publié dans: 2023
Éditeur: Cold Spring Harbor Laboratory
DOI: 10.1101/2023.09.18.558197

A genome-to-proteome atlas charts natural variants controlling proteome diversity and forecasts their fitness effects

Auteurs: Christopher M. Jakobson, Johannes Hartl, Pauline Trébulle, Michael Mülleder, Daniel F. Jarosz, Markus Ralser
Publié dans: 2024
Éditeur: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.10.18.619054

The GAPDH redox switch safeguards reductive capacity and enables survival of stressed tumour cells

Auteurs: Talwar D, Miller CG, Grossmann J, Szyrwiel L, Schwecke T, Demichev V, Drazic AM, Mayakonda A, Lutsik P, Veith C, Milsom MD, Müller-Decker K, Mülleder M, Ralser M, Dick TP.
Publié dans: Naturemetabolism, Numéro 5, 2023, Page(s) 660–676, ISSN 2522-5812
Éditeur: Nature
DOI: 10.1038/s42255-023-00781-3

Antifungal Tolerance and Resistance Emerge at Distinct Drug Concentrations and Rely upon Different Aneuploid Chromosomes

Auteurs: Feng Yang, Eduardo F. C. Scopel, Hao Li, Liu-liu Sun, Nora Kawar, Yong-bing Cao, Yuan-Ying Jiang, Judith Berman
Publié dans: mBio, Numéro 14, 2024, ISSN 2150-7511
Éditeur: American Society for Microbiology
DOI: 10.1128/mbio.00227-23

Reshaping Echinocandin Antifungal Drugs To Circumvent Glucan Synthase Point‐Mutation‐Mediated Resistance

Auteurs: Moriah Jospe‐Kaufman; Efrat Ben‐Zeev; Austin Mottola; Anna Dukhovny; Judith Berman; Shmuel Carmeli; Micha Fridman
Publié dans: Wiley online library, 2023, ISSN 1615-9853
Éditeur: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202314728

Interkingdom interactions between Pseudomonas aeruginosa and Candida albicans affect clinical outcomes and antimicrobial responses

Auteurs: Kahl LJ, Stremmel N, Esparza-Mora MA, Wheatley RM, MacLean RC, Ralser M.
Publié dans: Elsevier, 2023, ISSN 0959-437X
Éditeur: Elsevier BV
DOI: 10.1016/j.mib.2023.102368

Increasing the throughput of sensitive proteomics by plexDIA

Auteurs: Jason Derks, Andrew Leduc, Georg Wallmann, R. Gray Huffman, Matthew Willetts, Saad Khan, Harrison Specht, Markus Ralser, Vadim Demichev & Nikolai Slavov
Publié dans: Nature Biotechnology, Numéro 15461696, 2022, ISSN 1546-1696
Éditeur: Nature Biotechnology
DOI: 10.1038/s41587-022-01389-w

Quantitative protein biomarker panels: a path to improved clinical practice through proteomics

Auteurs: Hartl J, Kurth F, Kappert K, Horst D, Mülleder M, Hartmann G, Ralser M.
Publié dans: EMBO Molecular Medicine, 2023, ISSN 1757-4684
Éditeur: EMBO
DOI: 10.15252/emmm.202216061

Oxonium ion scanning mass spectrometry for large-scale plasma glycoproteomics

Auteurs: White MEH, Sinn LR, Jones DM, de Folter J, Aulakh SK, Wang Z, Flynn HR, Krüger L, Tober-Lau P, Demichev V, Kurth F, Mülleder M, Blanchard V, Messner CB, Ralser M.
Publié dans: Nature Biomedical Engineering, 2024, ISSN 2157-846X
Éditeur: Nature
DOI: 10.1038/s41551-023-01067-5

The importance of antimicrobial resistance in medical mycology

Auteurs: Neil A. R. Gow, Carolyn Johnson, Judith Berman, Alix T. Coste, Christina A. Cuomo, David S. Perlin, Tihana Bicanic, Thomas S. Harrison, Nathan Wiederhold, Mike Bromley, Tom Chiller & Keegan Edgar
Publié dans: Getting acquainted with npj Antimicrobials and Resistance, 2022, ISSN 2041-1723
Éditeur: Nature Publishing Group

Fast proteomics with dia‐PASEF and analytical flow‐rate chromatography

Auteurs: Lukasz Szyrwiel; Christoph Gille; Michael Mülleder; Vadim Demichev; Markus Ralser
Publié dans: Proteomics, 2023, ISSN 1615-9853
Éditeur: John Wiley & Sons Ltd.
DOI: 10.1002/pmic.202300100

The Metabolism of Susceptibility: Clearing the FoG Between Tolerance and Resistance in Candida albicans

Auteurs: Marina Druseikis, Austin Mottola, Judith Berman
Publié dans: Current Clinical Microbiology Reports, Numéro 10, 2024, Page(s) 36-46, ISSN 2196-5471
Éditeur: Springer Science and Business Media LLC
DOI: 10.1007/s40588-023-00189-3

The Impact of Acute Nutritional Interventions on the Plasma Proteome

Auteurs: Spyros I Vernardis; Vadim Demichev; Oliver Lemke; Nana-Maria Grüning; Christoph Messner; Matt White; Maik Pietzner; Alina Peluso; Tinh-Hai Collet; Elana Henning; Christoph Gille; Archie Campbell; Caroline Hayward; David J Porteous; Riccardo E Marioni; Michael Mülleder; Aleksej Zelezniak; Nicholas J Wareham; Claudia Langenberg; I Sadaf Farooqi; Markus Ralser
Publié dans: The Journal of clinical endocrinology and metabolism, vol. 108, no. 8 (2023) p. 2087-2098, Numéro 4, 2023, ISSN 0021-972X
Éditeur: The Endocrine Society

Metabolic exchanges are ubiquitous in natural microbial communities

Auteurs: Kost C, Patil KR, Friedman J, Garcia SL, Ralser M.
Publié dans: Nature Microbiology, 2023, ISSN 2058-5276
Éditeur: Nature Nicrobiology
DOI: 10.1038/s41564-023-01511-x

Integration of protein context improves protein-based COVID-19 patient stratification

Auteurs: Jinlong Gao, Jiale He, Fangfei Zhang, Qi Xiao, Xue Cai, Xiao Yi, Siqi Zheng, Ying Zhang, Donglian Wang, Guangjun Zhu, Jing Wang, Bo Shen, Markus Ralser, Tiannan Guo, Yi Zhu
Publié dans: Clinical Proteomics, Numéro 19, 2022, ISSN 1542-6416
Éditeur: Humana Press, Inc.
DOI: 10.1186/s12014-022-09370-0

Inorganic sulfur fixation via a new homocysteine synthase allows yeast cells to cooperatively compensate for methionine auxotrophy

Auteurs: Yu JSL, Heineike BM, Hartl J, Aulakh SK, Correia-Melo C, Lehmann A, Lemke O, Agostini F, Lee CT, Demichev V, Messner CB, Mülleder M, Ralser M.
Publié dans: PLOS Biology, 2022, ISSN 1544-9173
Éditeur: Public Library of Science
DOI: 10.1371/journal.pbio.3001912

Natural proteome diversity links aneuploidy tolerance to protein turnover

Auteurs: Julia Muenzner, Pauline Trébulle, Federica Agostini, Henrik Zauber, Christoph B. Messner, Martin Steger, Christiane Kilian, Kate Lau, Natalie Barthel, Andrea Lehmann, Kathrin Textoris-Taube, Elodie Caudal, Anna-Sophia Egger, Fatma Amari, Matteo De Chiara, Vadim Demichev, Toni I. Gossmann, Michael Mülleder, Gianni Liti, Joseph Schacherer, Matthias Selbach, Judith Berman, Markus Ralser
Publié dans: Nature, Numéro 630, 2024, Page(s) 149-157, ISSN 0028-0836
Éditeur: Nature Publishing Group
DOI: 10.1038/s41586-024-07442-9

A time-resolved proteomic and prognostic map of COVID-19

Auteurs: Vadim Demichev, Pinkus Tober-Lau, Oliver Lemke, Tatiana Nazarenko, Charlotte Thibeault, Harry Whitwell, Annika Röhl, Anja Freiwald, Lukasz Szyrwiel, Daniela Ludwig, Clara Correia-Melo, Simran Kaur Aulakh, Elisa T. Helbig, Paula Stubbemann, Lena J. Lippert, Nana-Maria Grüning, Oleg Blyuss, Spyros Vernardis, Matthew White, Christoph B. Messner, Michael Joannidis, Thomas Sonnweber, Sebastian J. Kle
Publié dans: Cell Systems, Numéro 12, 2024, Page(s) 780-794.e7, ISSN 2405-4712
Éditeur: Cell Press
DOI: 10.1016/j.cels.2021.05.005

The proteomic landscape of genome-wide genetic perturbations

Auteurs: Messner, Christoph B; Demichev, Vadim; Muenzner, Julia; Aulakh, Simran K; Barthel, Natalie; Röhl, Annika; Herrera-Domínguez, Lucía; Egger, Anna-Sophia; Kamrad, Stephan; Hou, Jing; Tan, Guihong; Lemke, Oliver; Calvani, Enrica; Szyrwiel, Lukasz; Mülleder, Michael; Lilley, Kathryn S; Boone, Charles; Kustatscher, Georg; Ralser, Markus
Publié dans: CELL, Numéro 186, 2023, ISSN 0092-8674
Éditeur: Cell Press
DOI: 10.1016/j.cell.2023.03.026

Spontaneously established syntrophic yeast communities improve bioproduction

Auteurs: Simran Kaur Aulakh, Lara Sellés Vidal, Eric J. South, Huadong Peng, Sreejith Jayasree Varma, Lucia Herrera-Dominguez, Markus Ralser, Rodrigo Ledesma-Amaro
Publié dans: Nature Chemical Biology, Numéro 19, 2023, Page(s) 951-961, ISSN 1552-4450
Éditeur: Nature Publishing Group
DOI: 10.1038/s41589-023-01341-2

Beyond resistance: antifungal heteroresistance and antifungal tolerance in fungal pathogens

Auteurs: Feng Yang; Judith Berman
Publié dans: Elsevier Current Opinion in Microbiology, 2023, ISSN 0959-437X
Éditeur: Elsevier BV
DOI: 10.1016/j.mib.2024.102439

An orthologous gene coevolution network provides insight into eukaryotic cellular and genomic structure and function

Auteurs: Jacob L. Steenwyk, Megan A. Phillips, Feng Yang, Swapneeta S. Date, Todd R. Graham, Judith Berman, Chris Todd Hittinger, Antonis Rokas
Publié dans: Science Advances, Numéro 8, 2024, ISSN 2375-2548
Éditeur: Science Advances
DOI: 10.1126/sciadv.abn0105

A live-cell ergosterol reporter for visualization of the effects of fluconazole on the human fungal pathogen Candida albicans

Auteurs: Antonio Serrano , Miguel A Basante-Bedoya, Martine Bassilan, Robert A Arkowitz
Publié dans: mBio, Numéro Nov 30;14(6), 2023, ISSN 2150-7511
Éditeur: American Society of Microbiology

The importance of antimicrobial resistance in medical mycology

Auteurs: Neil A. R. Gow, Carolyn Johnson, Judith Berman, Alix T. Coste, Christina A. Cuomo, David S. Perlin, Tihana Bicanic, Thomas S. Harrison, Nathan Wiederhold, Mike Bromley, Tom Chiller, Keegan Edgar
Publié dans: Nature Communications, Numéro 13, 2023, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-022-32249-5

The metabolic growth limitations of petite cells lacking the mitochondrial genome

Auteurs: Jakob Vowinckel, Johannes Hartl, Hans Marx, Martin Kerick, Kathrin Runggatscher, Markus A. Keller, Michael Mülleder, Jason Day, Manuela Weber, Mark Rinnerthaler, Jason S. L. Yu, Simran Kaur Aulakh, Andrea Lehmann, Diethard Mattanovich, Bernd Timmermann, Nianshu Zhang, Cory D. Dunn, James I. MacRae, Michael Breitenbach & Markus Ralser
Publié dans: Nature Metabolism, Numéro 25225812, 2021, ISSN 2522-5812
Éditeur: Nat. Metab.
DOI: 10.1038/s42255-021-00477-6

dia-PASEF data analysis using FragPipe and DIA-NN for deep proteomics of low sample amounts

Auteurs: Vadim Demichev, Lukasz Szyrwiel, Fengchao Yu, Guo Ci Teo, George Rosenberger, Agathe Niewienda, Daniela Ludwig, Jens Decker, Stephanie Kaspar-Schoenefeld, Kathryn S. Lilley, Michael Mülleder, Alexey I. Nesvizhskii & Markus Ralser
Publié dans: Nature Communications, Numéro 20411723, 2022, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-022-31492-0

The human host response to monkeypox infection: a proteomic case series study

Auteurs: Ziyue Wang, Pinkus Tober-Lau, ..., Markus Ralser, Florian Kurth
Publié dans: EMBO Molecular Medicine, 2022, ISSN 1757-4684
Éditeur: EMBO Press
DOI: 10.15252/emmm.202216643

Human aneuploid cells depend on the RAF/MEK/ERK pathway for overcoming increased DNA damage

Auteurs: Johanna Zerbib, Marica Rosaria Ippolito, Yonatan Eliezer, Giuseppina De Feudis, Eli Reuveni, Anouk Savir Kadmon, Sara Martin, Sonia Viganò, Gil Leor, James Berstler, Julia Muenzner, Michael Mülleder, Emma M. Campagnolo, Eldad D. Shulman, Tiangen Chang, Carmela Rubolino, Kathrin Laue, Yael Cohen-Sharir, Simone Scorzoni, Silvia Taglietti, Alice Ratti, Chani Stossel, Talia Golan, Francesco Nicassio
Publié dans: Nature Communications, Numéro 15, 2024, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-024-52176-x

High-throughput proteomics of nanogram-scale samples with Zeno SWATH MS

Auteurs: Wang Z, Mülleder M, Batruch I, Chelur A, Textoris-Taube K, Schwecke T, Hartl J, Causon J, Castro-Perez J, Demichev V, Tate S, Ralser M.
Publié dans: eLife, 2022, ISSN 2050-084X
Éditeur: eLife Sciences Publications
DOI: 10.7554/elife.83947

Metal ion availability and homeostasis as drivers of metabolic evolution and enzyme function

Auteurs: Aulakh SK, Varma SJ, Ralser M.
Publié dans: Science Direct, 2022, ISSN 1879-0380
Éditeur: Elsevier
DOI: 10.1016/j.gde.2022.101987

Reshaping Echinocandin Antifungal Drugs To Circumvent Glucan Synthase Point-Mutation-Mediated Resistance

Auteurs: Moriah Jospe-Kaufman, Dr. Efrat Ben-Zeev, Dr. Austin Mottola, Dr. Anna Dukhovny, Prof. Judith Berman, Prof. Shmuel Carmeli, Prof. Micha Fridman
Publié dans: NA, 2024, ISSN 1521-3773
Éditeur: Agwandte Chemie

Tackling the emerging threat of antifungal resistance to human health

Auteurs: Matthew C. Fisher, Ana Alastruey-Izquierdo, Judith Berman, Tihana Bicanic, Elaine M. Bignell, Paul Bowyer, Michael Bromley, Roger Brüggemann, Gary Garber, Oliver A. Cornely, Sarah. J. Gurr, Thomas S. Harrison, Ed Kuijper, Johanna Rhodes, Donald C. Sheppard, Adilia Warris, P. Lewis White, Jianping Xu, Bas Zwaan & Paul E. Verweij
Publié dans: Nature Reviews Microbiology, Numéro 17401534, 2022, ISSN 1740-1534
Éditeur: Nature
DOI: 10.1038/s41579-022-00720-1

Tunicamycin Potentiates Antifungal Drug Tolerance via Aneuploidy in Candida albicans

Auteurs: Feng Yang, Vladimir Gritsenko, Yaniv Slor Futterman, Lu Gao, Cheng Zhen, Hui Lu, Yuan-ying Jiang jiangyy@tongji.edu.cn, Judith Berman
Publié dans: mBio, Numéro 21507511, 2021, ISSN 2150-7511
Éditeur: ASM Journals
DOI: 10.1128/mbio.02272-21

Microbial communities form rich extracellular metabolomes that foster metabolic interactions and promote drug tolerance

Auteurs: Jason S. L. Yu, Clara Correia-Melo, Francisco Zorrilla, Lucia Herrera-Dominguez, Mary Y. Wu, Johannes Hartl, Kate Campbell, Sonja Blasche, Marco Kreidl, Anna-Sophia Egger, Christoph B. Messner, Vadim Demichev, Anja Freiwald, Michael Mülleder, Michael Howell, Judith Berman, Kiran R. Patil, Mohammad Tauqeer Alam & Markus Ralser
Publié dans: Nature Microbiology, Numéro 20585276, 2022, ISSN 2058-5276
Éditeur: Nat Microbiol
DOI: 10.1038/s41564-022-01072-5

Metabolic sensing tips the balance of drug tolerance in fungal meningitis

Auteurs: Mottola A, Hartl J, Ralser M, Berman J.
Publié dans: Nature Microbiology, 2024, ISSN 2058-5276
Éditeur: Nature
DOI: 10.1038/s41564-023-01595-5

The impact of phenotypic heterogeneity on fungal pathogenicity and drug resistance

Auteurs: Lukasz Kozubowski, Judith Berman
Publié dans: FEMS Microbiology Reviews, Numéro 49, 2025, ISSN 1574-6976
Éditeur: FEMS Microbiology Review
DOI: 10.1093/femsre/fuaf001

A multiplex protein panel assay for severity prediction and outcome prognosis in patients with COVID-19: An observational multi-cohort study

Auteurs: Ziyue Wang, Adam Cryar, Oliver Lemke, Pinkus Tober-Lau, Daniela Ludwig, Elisa Theresa Helbig, Stefan Hippenstiel, Leif-Erik Sander, Daniel Blake, Catherine S. Lane, Rebekah L. Sayers, Christoph Mueller, Johannes Zeiser, StJohn Townsend, Vadim Demichev, Michael Mülleder, Florian Kurth, Ernestas Sirka, Johannes Hartl, Markus Ralser
Publié dans: eClinicalMedicine, Numéro 49, 2023, Page(s) 101495, ISSN 2589-5370
Éditeur: Elsevier
DOI: 10.1016/j.eclinm.2022.101495

The Impact of Acute Nutritional Interventions on the Plasma Proteome

Auteurs: Spyros I Vernardis, Vadim Demichev, Oliver Lemke, Nana-Maria Grüning, Christoph Messner, Matt White, Maik Pietzner, Alina Peluso, Tinh-Hai Collet, Elana Henning, Christoph Gille, Archie Campbell, Caroline Hayward, David J Porteous, Riccardo E Marioni, Michael Mülleder, Aleksej Zelezniak, Nicholas J Wareham, Claudia Langenberg, I Sadaf Farooqi, Markus Ralser
Publié dans: The Journal of Clinical Endocrinology & Metabolism, Numéro 108, 2023, Page(s) 2087-2098, ISSN 0021-972X
Éditeur: The Endocrine Society
DOI: 10.1210/clinem/dgad031

Beyond resistance: antifungal heteroresistance and antifungal tolerance in fungal pathogens

Auteurs: Feng Yang, Judith Berman
Publié dans: Current Opinion in Microbiology, Numéro 78, 2024, Page(s) 102439, ISSN 1369-5274
Éditeur: Elsevier BV
DOI: 10.1016/j.mib.2024.102439

Step-wise evolution of azole resistance through copy number variation followed by KSR1 loss of heterozygosity in Candida albicans

Auteurs: Pétra Vande Zande, Cécile Gautier, Nora Kawar, Corinne Maufrais, Katura Metzner, Elizabeth Wash, Annette K. Beach, Ryan Bracken, Eli Isael Maciel, Nívea Pereira de Sá, Caroline Mota Fernandes, Norma V. Solis, Maurizio Del Poeta, Scott G. Filler, Judith Berman, Iuliana V. Ene, Anna Selmecki
Publié dans: PLOS Pathogens, Numéro 20, 2024, Page(s) e1012497, ISSN 1553-7374
Éditeur: PLOS
DOI: 10.1371/journal.ppat.1012497

Phylogenomics reveals extensive misidentification of fungal strains from the genus <i>Aspergillus</i>

Auteurs: Jacob L. Steenwyk, Charu Balamurugan, Huzefa A. Raja, Carla Gonçalves, Ningxiao Li, Frank Martin, Judith Berman, Nicholas H. Oberlies, John G. Gibbons, Gustavo H. Goldman, David M. Geiser, Jos Houbraken, David S. Hibbett, Antonis Rokas
Publié dans: Microbiology Spectrum, Numéro 12, 2024, ISSN 2165-0497
Éditeur: Microbiology Spectrum
DOI: 10.1128/spectrum.03980-23

Cell-cell metabolite exchange creates a pro-survival metabolic environment that extends lifespan

Auteurs: Correia-Melo C, Kamrad S, Tengölics R, Messner CB, Trebulle P, Townsend SJ, Varma SJ, Freiwald A, Heineike BM, Campbell K, Herrera-Dominguez L, Aulakh SK, Szyrwiel L, Yu JSL, Zelezniak A, Demichev V, Mülleder M, Papp B, Alam MT, Ralser M.
Publié dans: Cell Volume 186, Numéro 186, 2023, ISSN 0092-8674
Éditeur: Cell Press
DOI: 10.1016/j.cell.2022.12.007

Candida albicans exhibits heterogeneous and adaptive cytoprotective responses to antifungal compounds

Auteurs: Vanessa DumeauxSamira MassahiVan BettauerAustin MottolaAnna DukovnySanny Singh KhurdiaAnna Carolina Borges Pereira CostaRaha Parvizi OmranShawn SimpsonJinglin Lucy XieMalcolm WhitewayJudith BermanMichael T Hallett
Publié dans: Computational and Systems Biology, Microbiology and Infectious Disease, 2023, ISSN 2050-084X
Éditeur: eLife Sciences Publications

Antifungal Tolerance and Resistance Emerge at Distinct Drug Concentrations and Rely upon Different Aneuploid Chromosomes

Auteurs: Feng Yang https://orcid.org/0000-0003-2363-0745, Eduardo F. C. Scopel https://orcid.org/0000-0002-0064-3466, Hao Li, Liu-liu Sun, Nora Kawar, Yong-bing Cao, Yuan-Ying Jiang jiangyy@tongji.edu.cn, Judith Berman
Publié dans: ASM Journals, 2024, ISSN 2379-5077
Éditeur: ASM Journals

Mass spectrometry-based high-throughput proteomics and its role in biomedical studies and systems biology

Auteurs: Messner CB, Demichev V, Wang Z, Hartl J, Kustatscher G, Mülleder M, Ralser M.
Publié dans: Proteomics, 2022, ISSN 1615-9853
Éditeur: John Wiley & Sons Ltd.
DOI: 10.1002/pmic.202200013

The future of fungi: threats and opportunities

Auteurs: Nicola T Case, Judith Berman, David S Blehert, Robert A Cramer, Christina Cuomo, Cameron R Currie, Iuliana V Ene, Matthew C Fisher, Lillian K Fritz-Laylin, Aleeza C Gerstein, N Louise Glass, Neil A R Gow, Sarah J Gurr, Chris Todd Hittinger, Tobias M Hohl, Iliyan D Iliev, Timothy Y James, Hailing Jin, Bruce S Klein, James W Kronstad, Jeffrey M Lorch, Victoria McGovern, Aaron P Mitchell, Julia A Seg
Publié dans: G3, 2022, ISSN 2160-1836
Éditeur: Genetics Society of America

Collateral sensitivity counteracts the evolution of antifungal drug resistance in Candida auris

Auteurs: Hans Carolus, Dimitrios Sofras, Giorgio Boccarella, Stef Jacobs, Vladislav Biriukov, Louise Goossens, Alicia Chen, Ina Vantyghem, Tibo Verbeeck, Siebe Pierson, Celia Lobo Romero, Hans Steenackers, Katrien Lagrou, Pieter van den Berg, Judith Berman, Toni Gabaldón, Patrick Van Dijck
Publié dans: Nature Microbiology, Numéro 9, 2024, Page(s) 2954-2969, ISSN 2058-5276
Éditeur: Nature Microbiology
DOI: 10.1038/s41564-024-01811-w

Microbial communities form rich extracellular metabolomes that foster metabolic interactions and promote drug tolerance.

Auteurs: Jason S. L. Yu; Clara Correia-Melo; Francisco Zorrilla; Lucia Herrera-Dominguez; Mary Y. Wu; Johannes Hartl; Kate Campbell; Sonja Blasche; Marco Kreidl; Anna-Sophia Egger; Christoph B. Messner; Vadim Demichev; Anja Freiwald; Michael Mülleder; Michael Howell; Judith Berman; Kiran R. Patil; Mohammad Tauqeer Alam; Markus Ralser
Publié dans: Nature Microbiology, Numéro 4, 2022, Page(s) pages542–555, ISSN 2058-5276
Éditeur: NPG
DOI: 10.17863/cam.83116

Metabolic heterogeneity and cross-feeding within isogenic yeast populations captured by DILAC

Auteurs: Kamrad S, Correia-Melo C, Szyrwiel L, Aulakh SK, Bähler J, Demichev V, Mülleder M, Ralser M.
Publié dans: Nature Microbiology, 2023, ISSN 1087-0156
Éditeur: Nature Publishing Group
DOI: 10.1038/s41564-022-01304-8

Protocols for Measuring Tolerant and Heteroresistant Drug Responses of Pathogenic Yeasts

Auteurs: Naomi Lyons, Judith Berman
Publié dans: Methods in Molecular Biology, Antifungal Drug Resistance, 2023, Page(s) 67-79
Éditeur: Springer US
DOI: 10.1007/978-1-0716-3155-3_6

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