Molecular Bioengineering in health ERA chair

Project Information

MOBILIsE

Grant agreement ID: 951723

DOI

10.3030/951723

EC signature date 19 June 2020

Start date 1 January 2021

End date 30 June 2026

Funded under

• Establishing ‚ERA Chairs’

Total cost

€ 2 478 155,00

EU contribution

€ 2 478 155,00

Coordinated by

INEB-INSTITUTO NACIONAL DE ENGENHARIA BIOMEDICA
Portugal

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (4)

Self-assessment of INEB-i3S towards ERA priorities implementation

Report detailing how INEBi3S is positioned in line with the ERA priorities

Curricular plan of the Molecular Bioengineering Module

Report detailing a curricular plan focusing on Molecular Bioengineering for MSc and PhD programmes.

Training and Mentoring Plan

Report detailing main training and mentoring activities required

Dissemination Plan

MOBILIsE dissemination plan with regular updates at M12 M36 M60

Websites, patent fillings, videos etc. (1)

MOBILIsE website

Project website put online

Publications

Peer reviewed articles (27)

Bridging the gap between testing and clinics exploring alternative pre-clinical models in melanoma research

Author(s): Juliana Viegas, Bruno Sarmento
Published in: Advanced Drug Delivery Reviews, Issue 208, 2024, Page(s) 115295, ISSN 0169-409X
Publisher: Elsevier BV
DOI: 10.1016/j.addr.2024.115295

Dhvar5- and MSI78-coated titanium are bactericidal against methicillin-resistant Staphylococcus aureus, immunomodulatory and osteogenic

Author(s): B. Costa, J. Coelho, V. Silva, H. Shahrour, N.A. Costa, A.R. Ribeiro, S.G. Santos, F. Costa, G. Martínez-de-Tejada, C. Monteiro, M.C.L. Martins
Published in: Acta Biomaterialia, 2024, ISSN 1742-7061
Publisher: Elsevier BV
DOI: 10.1016/j.actbio.2024.11.016

Paving the way for a non-antibiotic and microbiota friendly therapy for Helicobacter pylori: In vitro and in vivo performance of lipid nanoparticles

Author(s): Catarina Leal Seabra, A. Sofia Pinho, Cláudia Nunes, Irina Amorim, Nicole Pedro, Patrícia Henriques, Cláudia Monteiro, Joana Gomes, Cláudia Machado, Fátima Gartner, Luísa Pereira, Salette Reis, Celso A. Reis, Eliette Touati, Inês C. Gonçalves, Paula Parreira, M. Cristina L. Martins
Published in: Helicobater, Issue 2024; 29: e13050., 2024, ISSN 1083-4389
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/hel.13050

How can biomaterial-conjugated antimicrobial peptides fight bacteria and be protected from degradation?

Author(s): Pedro M. Alves, Cristina C. Barrias, Paula Gomes, M. Cristina L. Martins
Published in: Acta Biomaterialia, Issue Volume 181, June 2024, 2024, Page(s) 98-116, ISSN 1742-7061
Publisher: Elsevier BV
DOI: 10.1016/j.actbio.2024.04.043

How Charge, Size and Protein Corona Modulate the Specific Activity of Nanostructured Lipid Carriers (NLC) against Helicobacter pylori

Author(s): Rute Chitas; Cláudia Nunes; Salette Reis; Paula Parreira; Maria Cristina L. Martins
Published in: Pharmaceutics, 2022, ISSN 1999-4923
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics14122745

Enhancement of hMSC In Vitro Proliferation by Surface Immobilization of a Heparin-Binding Peptide

Author(s): Maura Cimino, Paula Parreira, Victoria Leiro, Aureliana Sousa, Raquel M. Gonçalves, Cristina C. Barrias, M. Cristina L. Martins
Published in: Molecules, 2023, ISSN 1420-3049
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules28083422

Cholesterol Functionalized Nanoparticles Are Effective against <i>Helicobacter pylori</i>, the Gastric Bug: A Proof‐of‐Concept Study

Author(s): Ana Sofia Pinho, Renato Pereira, Mariana Pereira, Akhilesh Rai, Lino Ferreira, Maria Cristina Lopes Martins, Paula Parreira
Published in: Advanced Healthcare Materials, Issue 2025, 2404065, 2025, ISSN 2192-2640
Publisher: John Wiley and Sons Ltd
DOI: 10.1002/adhm.202404065

Abdominal wall hernia repair: from prosthetic meshes to smart materials

Author(s): Qimanguli Saiding, Yiyao Chen, Juan Wang, Catarina Leite Pereira, Bruno Sarmento, Wenguo Cui, Xinliang Chen
Published in: Materials Today Bio, 2023, ISSN 2590-0064
Publisher: Oxford: Elsevier Ltd
DOI: 10.1016/j.mtbio.2023.100691

Nanomedicine approaches for treating glioblastoma

Author(s): Cláudia Martins; Catarina Pacheco; Paulo Faria; Bruno Sarmento
Published in: Nanomedicine (Lond.), 2023, ISSN 1743-5889
Publisher: Future Medicine Ltd.
DOI: 10.2217/nnm-2023-0163

Structuring supramolecular hyaluronan hydrogels via peptide self-assembly for modulating the cell microenvironment

Author(s): Yichen Yuan, Yejiao Shi, Jayati Banerjee, Amin Sadeghpour, Helena S. Azevedo
Published in: Materials Today Bio, 2023, ISSN 2590-0064
Publisher: Oxford: Elsevier Ltd.
DOI: 10.1016/j.mtbio.2023.100598

Targeted nanotherapeutics for the treatment of Helicobacter pylori infection

Author(s): Rute Chitas, Diana R. Fonseca, Paula Parreira, M. Cristina L. Martins
Published in: Journal of Biomedical Science, Issue 31, 2024, ISSN 1423-0127
Publisher: BMC
DOI: 10.1186/s12929-024-01068-9

Organ-on-chip platforms for nanoparticle toxicity and efficacy assessment: Advancing beyond traditional in vitro and in vivo models

Author(s): Ana Regina Sampaio, Renata Faria Maia, Maria Camilla Ciardulli, Hélder A. Santos, Bruno Sarmento
Published in: Materials Today Bio, Issue 33, 2025, Page(s) 102053, ISSN 2590-0064
Publisher: Elsevier BV
DOI: 10.1016/j.mtbio.2025.102053

Exploring Low-Power Single-Pulsed Laser-Triggered Two-Photon Photodynamic/Photothermal Combination Therapy Using a Gold Nanostar/Graphene Quantum Dot Nanohybrid

Author(s): Amir Soleimany; Sepideh Khoee; Sofia Dias; Bruno Sarmento
Published in: ACS Applied Materials & Interfaces, 2023, ISSN 1944-8244
Publisher: American Chemical Society
DOI: 10.1021/acsami.3c03578

Influence of Immobilization Strategies on the Antibacterial Properties of Antimicrobial Peptide-Chitosan Coatings

Author(s): Mariana Barbosa; Pedro M. Alves; Fabíola Costa; Cláudia Monteiro; Paula Parreira; Cátia Teixeira; Paula Gomes; Maria Cristina L. Martins
Published in: Pharmaceuticals, 2023, ISSN 1999-4923
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics15051510

How to manage Helicobacter pylori infection beyond antibiotics: The bioengineering quest

Author(s): Diana R. Fonseca, Rute Chitas, Paula Parreira, M.Cristina L. Martins
Published in: Applied Materials Today, 2024, ISSN 2352-9407
Publisher: Elsevier Ltd.
DOI: 10.1016/j.apmt.2024.102123

Antimicrobial peptide-grafted PLGA-PEG nanoparticles to fight bacterial wound infections

Author(s): António Miguel Ramôa, Filipa Campos, Luís Moreira, Cátia Teixeira, Victoria Leiro, Paula Gomes, José das Neves, M. Cristina L. Martins, Cláudia Monteiro
Published in: Biomaterials Science, 2023, ISSN 2047-4849
Publisher: Royal Society of Chemistry
DOI: 10.1039/d2bm01127a

Hybrid structure combining essential oil derivatives and polydopamine for anti-bacterial coatings

Author(s): Nathan Jourdainne, Dimitri Mercier, Bruna Costa, Filipa Campos, Claudia Monteiro, Natália Costa, M. Cristina L. Martins, Pascal Thébault
Published in: Colloids and Surfaces B: Biointerfaces, Issue 252, 2025, Page(s) 114679, ISSN 0927-7765
Publisher: Elsevier BV
DOI: 10.1016/j.colsurfb.2025.114679

Peptide-based self-assembled monolayers (SAMs): what peptides can do for SAMs and vice versa

Author(s): Carlos Redondo-Gómez, Paula Parreira, M. Cristina L. Martins, and Helena S. Azevedo
Published in: Chemical Society Reviews, Issue "2024, ""Celebrating the scientific accomplishments of RSC Fellows""", 2024, ISSN 1460-4744
Publisher: Royal Society of Chemistry
DOI: 10.1039/d3cs00921a

Bioengineered hyaluronan hydrogels for the delivery of molecular and cellular therapies

Author(s): Joana Silva, Helena S. Azevedo
Published in: Advanced Therapeutics, 2023, ISSN 2366-3987
Publisher: John Wiley & Sons, Inc.
DOI: 10.1002/adtp.202300182

Phage Display Identified Peptide with Selectivity for Human Osteoarthritic Chondrocytes

Author(s): Ivone M. Martins, Raphaël F. Canadas, Hélder Pereira, Joana Azeredo, Rui L. Reis, Joaquim M. Oliveira, Helena S. Azevedo
Published in: Advanced Therapeutics, 2023, ISSN 2366-3987
Publisher: John Wiley & Sons, Inc.
DOI: 10.1002/adtp.202300263

Norbornene-chitosan nanoparticles with and without a conjugated VEGF-peptide analog to promote vascularization

Author(s): Pedro M. Alves, Diana R. Fonseca, Sílvia J. Bidarra, Ana Gomes, Paula Gomes, Cristina C. Barrias, M. Cristina L. Martins
Published in: Materials Today Chemistry, 2024, ISSN 2468-5194
Publisher: Science Direct, Elsevier
DOI: 10.1016/j.mtchem.2024.101942

Engineering resveratrol-loaded chitosan nanoparticles for potential use against Helicobacter pylori infection

Author(s): Larissa Spósito, Diana Fonseca, Suzana Gonçalves Carvalho, Rafael Miguel Sábio, Gabriel Davi Marena, Taís Maria Bauab, Andréia Bagliotti Meneguin, Paula Parreira, M. Cristina L. Martins, Marlus Chorilli
Published in: European Journal of Pharmaceutics and Biopharmaceutics, Issue 199, 2024, Page(s) 114280, ISSN 0939-6411
Publisher: Elsevier BV
DOI: 10.1016/j.ejpb.2024.114280

Validation of Selective Capture of Fimbriated Uropathogenic <i>Escherichia coli</i> by a Label-free Engineering Detection System Using Mannosylated Surfaces

Author(s): Leila Mousavifar; Paula Parreira; Alexis Taponard; Vanessa C. D. Graça; M. Cristina L. Martins; René Roy
Published in: ACS Applied Bio Materials, 2022, ISSN 2576-6422
Publisher: American Chemical Society
DOI: 10.1021/acsabm.2c00838

Norbornene-chitosan spray-dried microspheres for peptide conjugation using thiol-ene “photoclick” chemistry

Author(s): Pedro M. Alves; Diana R. Fonseca; Rúben F. Pereira; Berta N. Estevinho; Cátia Teixeira; Paula Gomes; M. Cristina L. Martins
Published in: Biomecánica, 2022, ISSN 1885-9518
Publisher: Sociedad Ibérica de Biomecánica y Biomateriales

"One-Pot Microfluidics to Engineer Chitosan Nanoparticles Conjugated with Antimicrobial Peptides Using “Photoclick” Chemistry: Validation Using the Gastric Bacterium Helicobacter pylori"""

Author(s): Diana R Fonseca, Pedro M. Alves, Estrela Neto, Beatriz Custódio, Sofia Guimarães, Duarte Moura, Francesca Annis, Marco Martins, Ana Gomes, Cátia Teixeira, Paula Gomes, Rúben F. Pereira, Paulo Freitas, Paula Parreira, and M. Cristina L. Martins
Published in: ACS Applied Materials & Interfaces, 2024, ISSN 1944-8244
Publisher: American Chemical Society
DOI: 10.1021/acsami.3c18772

Chemical engineering of zein with polyethylene glycol and Angiopep-2 to manufacture a brain-targeted docetaxel nanomedicine for glioblastoma treatment

Author(s): Seem Awad, Marco Araújo, Paulo Faria, Bruno Sarmento, Cláudia Martins
Published in: Drug Delivery and Translational Research, 2024, ISSN 2190-393X
Publisher: Springer Pub. Co.,
DOI: 10.1007/s13346-024-01659-x

Dhvar5-chitosan nanogels and their potential to improve antibiotics activity

Author(s): B. Costa, P.M. Alves, D.R. Fonseca, F. Campos, A.C. Monteiro, H. Shahrour, A. Gomes, F. Costa, P. Gomes, G. Martínez-de-Tejada, C. Monteiro, M.C.L. Martins
Published in: International Journal of Biological Macromolecules, Issue 277, 2024, Page(s) 134059, ISSN 0141-8130
Publisher: Elsevier BV
DOI: 10.1016/j.ijbiomac.2024.134059