Molecular Bioengineering in health ERA chair

Livrables

Self-assessment of INEB-i3S towards ERA priorities implementation

Report detailing how INEBi3S is positioned in line with the ERA priorities

MOBILIsE dissemination plan with regular updates at M12 M36 M60

Project website put online

Publications

Paving the way for a non-antibiotic and microbiota friendly therapy for Helicobacter pylori: In vitro and in vivo performance of lipid nanoparticles

Auteurs: Catarina Leal Seabra, A. Sofia Pinho, Cláudia Nunes, Irina Amorim, Nicole Pedro, Patrícia Henriques, Cláudia Monteiro, Joana Gomes, Cláudia Machado, Fátima Gartner, Luísa Pereira, Salette Reis, Celso A. Reis, Eliette Touati, Inês C. Gonçalves, Paula Parreira, M. Cristina L. Martins
Publié dans: Helicobater, Numéro 2024; 29: e13050., 2024, ISSN 1083-4389
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/hel.13050

How can biomaterial-conjugated antimicrobial peptides fight bacteria and be protected from degradation?

Auteurs: Pedro M. Alves, Cristina C. Barrias, Paula Gomes, M. Cristina L. Martins
Publié dans: Acta Biomaterialia, Numéro Volume 181, June 2024, 2024, Page(s) 98-116, ISSN 1742-7061
Éditeur: Elsevier BV
DOI: 10.1016/j.actbio.2024.04.043

How Charge, Size and Protein Corona Modulate the Specific Activity of Nanostructured Lipid Carriers (NLC) against Helicobacter pylori

Auteurs: Rute Chitas; Cláudia Nunes; Salette Reis; Paula Parreira; Maria Cristina L. Martins
Publié dans: Pharmaceutics, 2022, ISSN 1999-4923
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics14122745

Enhancement of hMSC In Vitro Proliferation by Surface Immobilization of a Heparin-Binding Peptide

Auteurs: Maura Cimino, Paula Parreira, Victoria Leiro, Aureliana Sousa, Raquel M. Gonçalves, Cristina C. Barrias, M. Cristina L. Martins
Publié dans: Molecules, 2023, ISSN 1420-3049
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules28083422

Abdominal wall hernia repair: from prosthetic meshes to smart materials

Auteurs: Qimanguli Saiding, Yiyao Chen, Juan Wang, Catarina Leite Pereira, Bruno Sarmento, Wenguo Cui, Xinliang Chen
Publié dans: Materials Today Bio, 2023, ISSN 2590-0064
Éditeur: Oxford: Elsevier Ltd
DOI: 10.1016/j.mtbio.2023.100691

Nanomedicine approaches for treating glioblastoma

Auteurs: Cláudia Martins; Catarina Pacheco; Paulo Faria; Bruno Sarmento
Publié dans: Nanomedicine (Lond.), 2023, ISSN 1743-5889
Éditeur: Future Medicine Ltd.
DOI: 10.2217/nnm-2023-0163

Structuring supramolecular hyaluronan hydrogels via peptide self-assembly for modulating the cell microenvironment

Auteurs: Yichen Yuan, Yejiao Shi, Jayati Banerjee, Amin Sadeghpour, Helena S. Azevedo
Publié dans: Materials Today Bio, 2023, ISSN 2590-0064
Éditeur: Oxford: Elsevier Ltd.
DOI: 10.1016/j.mtbio.2023.100598

Exploring Low-Power Single-Pulsed Laser-Triggered Two-Photon Photodynamic/Photothermal Combination Therapy Using a Gold Nanostar/Graphene Quantum Dot Nanohybrid

Auteurs: Amir Soleimany; Sepideh Khoee; Sofia Dias; Bruno Sarmento
Publié dans: ACS Applied Materials & Interfaces, 2023, ISSN 1944-8244
Éditeur: American Chemical Society
DOI: 10.1021/acsami.3c03578

Influence of Immobilization Strategies on the Antibacterial Properties of Antimicrobial Peptide-Chitosan Coatings

Auteurs: Mariana Barbosa; Pedro M. Alves; Fabíola Costa; Cláudia Monteiro; Paula Parreira; Cátia Teixeira; Paula Gomes; Maria Cristina L. Martins
Publié dans: Pharmaceuticals, 2023, ISSN 1999-4923
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics15051510

How to manage Helicobacter pylori infection beyond antibiotics: The bioengineering quest

Auteurs: Diana R. Fonseca, Rute Chitas, Paula Parreira, M.Cristina L. Martins
Publié dans: Applied Materials Today, 2024, ISSN 2352-9407
Éditeur: Elsevier Ltd.
DOI: 10.1016/j.apmt.2024.102123

Antimicrobial peptide-grafted PLGA-PEG nanoparticles to fight bacterial wound infections

Auteurs: António Miguel Ramôa, Filipa Campos, Luís Moreira, Cátia Teixeira, Victoria Leiro, Paula Gomes, José das Neves, M. Cristina L. Martins, Cláudia Monteiro
Publié dans: Biomaterials Science, 2023, ISSN 2047-4849
Éditeur: Royal Society of Chemistry
DOI: 10.1039/d2bm01127a

Peptide-based self-assembled monolayers (SAMs): what peptides can do for SAMs and vice versa

Auteurs: Carlos Redondo-Gómez, Paula Parreira, M. Cristina L. Martins, and Helena S. Azevedo
Publié dans: Chemical Society Reviews, Numéro "2024, ""Celebrating the scientific accomplishments of RSC Fellows""", 2024, ISSN 1460-4744
Éditeur: Royal Society of Chemistry
DOI: 10.1039/d3cs00921a

Bioengineered hyaluronan hydrogels for the delivery of molecular and cellular therapies

Auteurs: Joana Silva, Helena S. Azevedo
Publié dans: Advanced Therapeutics, 2023, ISSN 2366-3987
Éditeur: John Wiley & Sons, Inc.
DOI: 10.1002/adtp.202300182

Phage Display Identified Peptide with Selectivity for Human Osteoarthritic Chondrocytes

Auteurs: Ivone M. Martins, Raphaël F. Canadas, Hélder Pereira, Joana Azeredo, Rui L. Reis, Joaquim M. Oliveira, Helena S. Azevedo
Publié dans: Advanced Therapeutics, 2023, ISSN 2366-3987
Éditeur: John Wiley & Sons, Inc.
DOI: 10.1002/adtp.202300263

Norbornene-chitosan nanoparticles with and without a conjugated VEGF-peptide analog to promote vascularization

Auteurs: Pedro M. Alves, Diana R. Fonseca, Sílvia J. Bidarra, Ana Gomes, Paula Gomes, Cristina C. Barrias, M. Cristina L. Martins
Publié dans: Materials Today Chemistry, 2024, ISSN 2468-5194
Éditeur: Science Direct, Elsevier
DOI: 10.1016/j.mtchem.2024.101942

Validation of Selective Capture of Fimbriated Uropathogenic <i>Escherichia coli</i> by a Label-free Engineering Detection System Using Mannosylated Surfaces

Auteurs: Leila Mousavifar; Paula Parreira; Alexis Taponard; Vanessa C. D. Graça; M. Cristina L. Martins; René Roy
Publié dans: ACS Applied Bio Materials, 2022, ISSN 2576-6422
Éditeur: American Chemical Society
DOI: 10.1021/acsabm.2c00838

Norbornene-chitosan spray-dried microspheres for peptide conjugation using thiol-ene “photoclick” chemistry

Auteurs: Pedro M. Alves; Diana R. Fonseca; Rúben F. Pereira; Berta N. Estevinho; Cátia Teixeira; Paula Gomes; M. Cristina L. Martins
Publié dans: Biomecánica, 2022, ISSN 1885-9518
Éditeur: Sociedad Ibérica de Biomecánica y Biomateriales

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