Molecular Bioengineering in health ERA chair

Informations projet

MOBILIsE

N° de convention de subvention: 951723

DOI

10.3030/951723

Date de signature de la CE 19 Juin 2020

Date de début 1 Janvier 2021

Date de fin 30 Juin 2026

Financé au titre de

• Establishing ‚ERA Chairs’

Coût total

€ 2 478 155,00

Contribution de l’UE

€ 2 478 155,00

Coordonné par

INEB-INSTITUTO NACIONAL DE ENGENHARIA BIOMEDICA
Portugal

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Documents, reports (4)

Self-assessment of INEB-i3S towards ERA priorities implementation

Report detailing how INEBi3S is positioned in line with the ERA priorities

Curricular plan of the Molecular Bioengineering Module

Report detailing a curricular plan focusing on Molecular Bioengineering for MSc and PhD programmes.

Training and Mentoring Plan

Report detailing main training and mentoring activities required

Dissemination Plan

MOBILIsE dissemination plan with regular updates at M12 M36 M60

Websites, patent fillings, videos etc. (1)

MOBILIsE website

Project website put online

Publications

Peer reviewed articles (27)

Bridging the gap between testing and clinics exploring alternative pre-clinical models in melanoma research

Auteurs: Juliana Viegas, Bruno Sarmento
Publié dans: Advanced Drug Delivery Reviews, Numéro 208, 2024, Page(s) 115295, ISSN 0169-409X
Éditeur: Elsevier BV
DOI: 10.1016/j.addr.2024.115295

Dhvar5- and MSI78-coated titanium are bactericidal against methicillin-resistant Staphylococcus aureus, immunomodulatory and osteogenic

Auteurs: B. Costa, J. Coelho, V. Silva, H. Shahrour, N.A. Costa, A.R. Ribeiro, S.G. Santos, F. Costa, G. Martínez-de-Tejada, C. Monteiro, M.C.L. Martins
Publié dans: Acta Biomaterialia, 2024, ISSN 1742-7061
Éditeur: Elsevier BV
DOI: 10.1016/j.actbio.2024.11.016

Paving the way for a non-antibiotic and microbiota friendly therapy for Helicobacter pylori: In vitro and in vivo performance of lipid nanoparticles

Auteurs: Catarina Leal Seabra, A. Sofia Pinho, Cláudia Nunes, Irina Amorim, Nicole Pedro, Patrícia Henriques, Cláudia Monteiro, Joana Gomes, Cláudia Machado, Fátima Gartner, Luísa Pereira, Salette Reis, Celso A. Reis, Eliette Touati, Inês C. Gonçalves, Paula Parreira, M. Cristina L. Martins
Publié dans: Helicobater, Numéro 2024; 29: e13050., 2024, ISSN 1083-4389
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/hel.13050

How can biomaterial-conjugated antimicrobial peptides fight bacteria and be protected from degradation?

Auteurs: Pedro M. Alves, Cristina C. Barrias, Paula Gomes, M. Cristina L. Martins
Publié dans: Acta Biomaterialia, Numéro Volume 181, June 2024, 2024, Page(s) 98-116, ISSN 1742-7061
Éditeur: Elsevier BV
DOI: 10.1016/j.actbio.2024.04.043

How Charge, Size and Protein Corona Modulate the Specific Activity of Nanostructured Lipid Carriers (NLC) against Helicobacter pylori

Auteurs: Rute Chitas; Cláudia Nunes; Salette Reis; Paula Parreira; Maria Cristina L. Martins
Publié dans: Pharmaceutics, 2022, ISSN 1999-4923
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics14122745

Enhancement of hMSC In Vitro Proliferation by Surface Immobilization of a Heparin-Binding Peptide

Auteurs: Maura Cimino, Paula Parreira, Victoria Leiro, Aureliana Sousa, Raquel M. Gonçalves, Cristina C. Barrias, M. Cristina L. Martins
Publié dans: Molecules, 2023, ISSN 1420-3049
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules28083422

Cholesterol Functionalized Nanoparticles Are Effective against <i>Helicobacter pylori</i>, the Gastric Bug: A Proof‐of‐Concept Study

Auteurs: Ana Sofia Pinho, Renato Pereira, Mariana Pereira, Akhilesh Rai, Lino Ferreira, Maria Cristina Lopes Martins, Paula Parreira
Publié dans: Advanced Healthcare Materials, Numéro 2025, 2404065, 2025, ISSN 2192-2640
Éditeur: John Wiley and Sons Ltd
DOI: 10.1002/adhm.202404065

Abdominal wall hernia repair: from prosthetic meshes to smart materials

Auteurs: Qimanguli Saiding, Yiyao Chen, Juan Wang, Catarina Leite Pereira, Bruno Sarmento, Wenguo Cui, Xinliang Chen
Publié dans: Materials Today Bio, 2023, ISSN 2590-0064
Éditeur: Oxford: Elsevier Ltd
DOI: 10.1016/j.mtbio.2023.100691

Nanomedicine approaches for treating glioblastoma

Auteurs: Cláudia Martins; Catarina Pacheco; Paulo Faria; Bruno Sarmento
Publié dans: Nanomedicine (Lond.), 2023, ISSN 1743-5889
Éditeur: Future Medicine Ltd.
DOI: 10.2217/nnm-2023-0163

Structuring supramolecular hyaluronan hydrogels via peptide self-assembly for modulating the cell microenvironment

Auteurs: Yichen Yuan, Yejiao Shi, Jayati Banerjee, Amin Sadeghpour, Helena S. Azevedo
Publié dans: Materials Today Bio, 2023, ISSN 2590-0064
Éditeur: Oxford: Elsevier Ltd.
DOI: 10.1016/j.mtbio.2023.100598

Targeted nanotherapeutics for the treatment of Helicobacter pylori infection

Auteurs: Rute Chitas, Diana R. Fonseca, Paula Parreira, M. Cristina L. Martins
Publié dans: Journal of Biomedical Science, Numéro 31, 2024, ISSN 1423-0127
Éditeur: BMC
DOI: 10.1186/s12929-024-01068-9

Organ-on-chip platforms for nanoparticle toxicity and efficacy assessment: Advancing beyond traditional in vitro and in vivo models

Auteurs: Ana Regina Sampaio, Renata Faria Maia, Maria Camilla Ciardulli, Hélder A. Santos, Bruno Sarmento
Publié dans: Materials Today Bio, Numéro 33, 2025, Page(s) 102053, ISSN 2590-0064
Éditeur: Elsevier BV
DOI: 10.1016/j.mtbio.2025.102053

Exploring Low-Power Single-Pulsed Laser-Triggered Two-Photon Photodynamic/Photothermal Combination Therapy Using a Gold Nanostar/Graphene Quantum Dot Nanohybrid

Auteurs: Amir Soleimany; Sepideh Khoee; Sofia Dias; Bruno Sarmento
Publié dans: ACS Applied Materials & Interfaces, 2023, ISSN 1944-8244
Éditeur: American Chemical Society
DOI: 10.1021/acsami.3c03578

Influence of Immobilization Strategies on the Antibacterial Properties of Antimicrobial Peptide-Chitosan Coatings

Auteurs: Mariana Barbosa; Pedro M. Alves; Fabíola Costa; Cláudia Monteiro; Paula Parreira; Cátia Teixeira; Paula Gomes; Maria Cristina L. Martins
Publié dans: Pharmaceuticals, 2023, ISSN 1999-4923
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics15051510

How to manage Helicobacter pylori infection beyond antibiotics: The bioengineering quest

Auteurs: Diana R. Fonseca, Rute Chitas, Paula Parreira, M.Cristina L. Martins
Publié dans: Applied Materials Today, 2024, ISSN 2352-9407
Éditeur: Elsevier Ltd.
DOI: 10.1016/j.apmt.2024.102123

Antimicrobial peptide-grafted PLGA-PEG nanoparticles to fight bacterial wound infections

Auteurs: António Miguel Ramôa, Filipa Campos, Luís Moreira, Cátia Teixeira, Victoria Leiro, Paula Gomes, José das Neves, M. Cristina L. Martins, Cláudia Monteiro
Publié dans: Biomaterials Science, 2023, ISSN 2047-4849
Éditeur: Royal Society of Chemistry
DOI: 10.1039/d2bm01127a

Hybrid structure combining essential oil derivatives and polydopamine for anti-bacterial coatings

Auteurs: Nathan Jourdainne, Dimitri Mercier, Bruna Costa, Filipa Campos, Claudia Monteiro, Natália Costa, M. Cristina L. Martins, Pascal Thébault
Publié dans: Colloids and Surfaces B: Biointerfaces, Numéro 252, 2025, Page(s) 114679, ISSN 0927-7765
Éditeur: Elsevier BV
DOI: 10.1016/j.colsurfb.2025.114679

Peptide-based self-assembled monolayers (SAMs): what peptides can do for SAMs and vice versa

Auteurs: Carlos Redondo-Gómez, Paula Parreira, M. Cristina L. Martins, and Helena S. Azevedo
Publié dans: Chemical Society Reviews, Numéro "2024, ""Celebrating the scientific accomplishments of RSC Fellows""", 2024, ISSN 1460-4744
Éditeur: Royal Society of Chemistry
DOI: 10.1039/d3cs00921a

Bioengineered hyaluronan hydrogels for the delivery of molecular and cellular therapies

Auteurs: Joana Silva, Helena S. Azevedo
Publié dans: Advanced Therapeutics, 2023, ISSN 2366-3987
Éditeur: John Wiley & Sons, Inc.
DOI: 10.1002/adtp.202300182

Phage Display Identified Peptide with Selectivity for Human Osteoarthritic Chondrocytes

Auteurs: Ivone M. Martins, Raphaël F. Canadas, Hélder Pereira, Joana Azeredo, Rui L. Reis, Joaquim M. Oliveira, Helena S. Azevedo
Publié dans: Advanced Therapeutics, 2023, ISSN 2366-3987
Éditeur: John Wiley & Sons, Inc.
DOI: 10.1002/adtp.202300263

Norbornene-chitosan nanoparticles with and without a conjugated VEGF-peptide analog to promote vascularization

Auteurs: Pedro M. Alves, Diana R. Fonseca, Sílvia J. Bidarra, Ana Gomes, Paula Gomes, Cristina C. Barrias, M. Cristina L. Martins
Publié dans: Materials Today Chemistry, 2024, ISSN 2468-5194
Éditeur: Science Direct, Elsevier
DOI: 10.1016/j.mtchem.2024.101942

Engineering resveratrol-loaded chitosan nanoparticles for potential use against Helicobacter pylori infection

Auteurs: Larissa Spósito, Diana Fonseca, Suzana Gonçalves Carvalho, Rafael Miguel Sábio, Gabriel Davi Marena, Taís Maria Bauab, Andréia Bagliotti Meneguin, Paula Parreira, M. Cristina L. Martins, Marlus Chorilli
Publié dans: European Journal of Pharmaceutics and Biopharmaceutics, Numéro 199, 2024, Page(s) 114280, ISSN 0939-6411
Éditeur: Elsevier BV
DOI: 10.1016/j.ejpb.2024.114280

Validation of Selective Capture of Fimbriated Uropathogenic <i>Escherichia coli</i> by a Label-free Engineering Detection System Using Mannosylated Surfaces

Auteurs: Leila Mousavifar; Paula Parreira; Alexis Taponard; Vanessa C. D. Graça; M. Cristina L. Martins; René Roy
Publié dans: ACS Applied Bio Materials, 2022, ISSN 2576-6422
Éditeur: American Chemical Society
DOI: 10.1021/acsabm.2c00838

Norbornene-chitosan spray-dried microspheres for peptide conjugation using thiol-ene “photoclick” chemistry

Auteurs: Pedro M. Alves; Diana R. Fonseca; Rúben F. Pereira; Berta N. Estevinho; Cátia Teixeira; Paula Gomes; M. Cristina L. Martins
Publié dans: Biomecánica, 2022, ISSN 1885-9518
Éditeur: Sociedad Ibérica de Biomecánica y Biomateriales

"One-Pot Microfluidics to Engineer Chitosan Nanoparticles Conjugated with Antimicrobial Peptides Using “Photoclick” Chemistry: Validation Using the Gastric Bacterium Helicobacter pylori"""

Auteurs: Diana R Fonseca, Pedro M. Alves, Estrela Neto, Beatriz Custódio, Sofia Guimarães, Duarte Moura, Francesca Annis, Marco Martins, Ana Gomes, Cátia Teixeira, Paula Gomes, Rúben F. Pereira, Paulo Freitas, Paula Parreira, and M. Cristina L. Martins
Publié dans: ACS Applied Materials & Interfaces, 2024, ISSN 1944-8244
Éditeur: American Chemical Society
DOI: 10.1021/acsami.3c18772

Chemical engineering of zein with polyethylene glycol and Angiopep-2 to manufacture a brain-targeted docetaxel nanomedicine for glioblastoma treatment

Auteurs: Seem Awad, Marco Araújo, Paulo Faria, Bruno Sarmento, Cláudia Martins
Publié dans: Drug Delivery and Translational Research, 2024, ISSN 2190-393X
Éditeur: Springer Pub. Co.,
DOI: 10.1007/s13346-024-01659-x

Dhvar5-chitosan nanogels and their potential to improve antibiotics activity

Auteurs: B. Costa, P.M. Alves, D.R. Fonseca, F. Campos, A.C. Monteiro, H. Shahrour, A. Gomes, F. Costa, P. Gomes, G. Martínez-de-Tejada, C. Monteiro, M.C.L. Martins
Publié dans: International Journal of Biological Macromolecules, Numéro 277, 2024, Page(s) 134059, ISSN 0141-8130
Éditeur: Elsevier BV
DOI: 10.1016/j.ijbiomac.2024.134059