Molecular Bioengineering in health ERA chair

Información del proyecto

MOBILIsE

Identificador del acuerdo de subvención: 951723

DOI

10.3030/951723

Fecha de la firma de la CE 19 Junio 2020

Fecha de inicio 1 Enero 2021

Fecha de finalización 30 Junio 2026

Financiado con arreglo a

• Establishing ‚ERA Chairs’

Coste total

€ 2 478 155,00

Aportación de la UE

€ 2 478 155,00

Coordinado por

INEB-INSTITUTO NACIONAL DE ENGENHARIA BIOMEDICA
Portugal

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Documents, reports (4)

Self-assessment of INEB-i3S towards ERA priorities implementation

Report detailing how INEBi3S is positioned in line with the ERA priorities

Curricular plan of the Molecular Bioengineering Module

Report detailing a curricular plan focusing on Molecular Bioengineering for MSc and PhD programmes.

Training and Mentoring Plan

Report detailing main training and mentoring activities required

Dissemination Plan

MOBILIsE dissemination plan with regular updates at M12 M36 M60

Websites, patent fillings, videos etc. (1)

MOBILIsE website

Project website put online

Publicaciones

Peer reviewed articles (27)

Bridging the gap between testing and clinics exploring alternative pre-clinical models in melanoma research

Autores: Juliana Viegas, Bruno Sarmento
Publicado en: Advanced Drug Delivery Reviews, Edición 208, 2024, Página(s) 115295, ISSN 0169-409X
Editor: Elsevier BV
DOI: 10.1016/j.addr.2024.115295

Dhvar5- and MSI78-coated titanium are bactericidal against methicillin-resistant Staphylococcus aureus, immunomodulatory and osteogenic

Autores: B. Costa, J. Coelho, V. Silva, H. Shahrour, N.A. Costa, A.R. Ribeiro, S.G. Santos, F. Costa, G. Martínez-de-Tejada, C. Monteiro, M.C.L. Martins
Publicado en: Acta Biomaterialia, 2024, ISSN 1742-7061
Editor: Elsevier BV
DOI: 10.1016/j.actbio.2024.11.016

Paving the way for a non-antibiotic and microbiota friendly therapy for Helicobacter pylori: In vitro and in vivo performance of lipid nanoparticles

Autores: Catarina Leal Seabra, A. Sofia Pinho, Cláudia Nunes, Irina Amorim, Nicole Pedro, Patrícia Henriques, Cláudia Monteiro, Joana Gomes, Cláudia Machado, Fátima Gartner, Luísa Pereira, Salette Reis, Celso A. Reis, Eliette Touati, Inês C. Gonçalves, Paula Parreira, M. Cristina L. Martins
Publicado en: Helicobater, Edición 2024; 29: e13050., 2024, ISSN 1083-4389
Editor: Blackwell Publishing Inc.
DOI: 10.1111/hel.13050

How can biomaterial-conjugated antimicrobial peptides fight bacteria and be protected from degradation?

Autores: Pedro M. Alves, Cristina C. Barrias, Paula Gomes, M. Cristina L. Martins
Publicado en: Acta Biomaterialia, Edición Volume 181, June 2024, 2024, Página(s) 98-116, ISSN 1742-7061
Editor: Elsevier BV
DOI: 10.1016/j.actbio.2024.04.043

How Charge, Size and Protein Corona Modulate the Specific Activity of Nanostructured Lipid Carriers (NLC) against Helicobacter pylori

Autores: Rute Chitas; Cláudia Nunes; Salette Reis; Paula Parreira; Maria Cristina L. Martins
Publicado en: Pharmaceutics, 2022, ISSN 1999-4923
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics14122745

Enhancement of hMSC In Vitro Proliferation by Surface Immobilization of a Heparin-Binding Peptide

Autores: Maura Cimino, Paula Parreira, Victoria Leiro, Aureliana Sousa, Raquel M. Gonçalves, Cristina C. Barrias, M. Cristina L. Martins
Publicado en: Molecules, 2023, ISSN 1420-3049
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules28083422

Cholesterol Functionalized Nanoparticles Are Effective against <i>Helicobacter pylori</i>, the Gastric Bug: A Proof‐of‐Concept Study

Autores: Ana Sofia Pinho, Renato Pereira, Mariana Pereira, Akhilesh Rai, Lino Ferreira, Maria Cristina Lopes Martins, Paula Parreira
Publicado en: Advanced Healthcare Materials, Edición 2025, 2404065, 2025, ISSN 2192-2640
Editor: John Wiley and Sons Ltd
DOI: 10.1002/adhm.202404065

Abdominal wall hernia repair: from prosthetic meshes to smart materials

Autores: Qimanguli Saiding, Yiyao Chen, Juan Wang, Catarina Leite Pereira, Bruno Sarmento, Wenguo Cui, Xinliang Chen
Publicado en: Materials Today Bio, 2023, ISSN 2590-0064
Editor: Oxford: Elsevier Ltd
DOI: 10.1016/j.mtbio.2023.100691

Nanomedicine approaches for treating glioblastoma

Autores: Cláudia Martins; Catarina Pacheco; Paulo Faria; Bruno Sarmento
Publicado en: Nanomedicine (Lond.), 2023, ISSN 1743-5889
Editor: Future Medicine Ltd.
DOI: 10.2217/nnm-2023-0163

Structuring supramolecular hyaluronan hydrogels via peptide self-assembly for modulating the cell microenvironment

Autores: Yichen Yuan, Yejiao Shi, Jayati Banerjee, Amin Sadeghpour, Helena S. Azevedo
Publicado en: Materials Today Bio, 2023, ISSN 2590-0064
Editor: Oxford: Elsevier Ltd.
DOI: 10.1016/j.mtbio.2023.100598

Targeted nanotherapeutics for the treatment of Helicobacter pylori infection

Autores: Rute Chitas, Diana R. Fonseca, Paula Parreira, M. Cristina L. Martins
Publicado en: Journal of Biomedical Science, Edición 31, 2024, ISSN 1423-0127
Editor: BMC
DOI: 10.1186/s12929-024-01068-9

Organ-on-chip platforms for nanoparticle toxicity and efficacy assessment: Advancing beyond traditional in vitro and in vivo models

Autores: Ana Regina Sampaio, Renata Faria Maia, Maria Camilla Ciardulli, Hélder A. Santos, Bruno Sarmento
Publicado en: Materials Today Bio, Edición 33, 2025, Página(s) 102053, ISSN 2590-0064
Editor: Elsevier BV
DOI: 10.1016/j.mtbio.2025.102053

Exploring Low-Power Single-Pulsed Laser-Triggered Two-Photon Photodynamic/Photothermal Combination Therapy Using a Gold Nanostar/Graphene Quantum Dot Nanohybrid

Autores: Amir Soleimany; Sepideh Khoee; Sofia Dias; Bruno Sarmento
Publicado en: ACS Applied Materials & Interfaces, 2023, ISSN 1944-8244
Editor: American Chemical Society
DOI: 10.1021/acsami.3c03578

Influence of Immobilization Strategies on the Antibacterial Properties of Antimicrobial Peptide-Chitosan Coatings

Autores: Mariana Barbosa; Pedro M. Alves; Fabíola Costa; Cláudia Monteiro; Paula Parreira; Cátia Teixeira; Paula Gomes; Maria Cristina L. Martins
Publicado en: Pharmaceuticals, 2023, ISSN 1999-4923
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics15051510

How to manage Helicobacter pylori infection beyond antibiotics: The bioengineering quest

Autores: Diana R. Fonseca, Rute Chitas, Paula Parreira, M.Cristina L. Martins
Publicado en: Applied Materials Today, 2024, ISSN 2352-9407
Editor: Elsevier Ltd.
DOI: 10.1016/j.apmt.2024.102123

Antimicrobial peptide-grafted PLGA-PEG nanoparticles to fight bacterial wound infections

Autores: António Miguel Ramôa, Filipa Campos, Luís Moreira, Cátia Teixeira, Victoria Leiro, Paula Gomes, José das Neves, M. Cristina L. Martins, Cláudia Monteiro
Publicado en: Biomaterials Science, 2023, ISSN 2047-4849
Editor: Royal Society of Chemistry
DOI: 10.1039/d2bm01127a

Hybrid structure combining essential oil derivatives and polydopamine for anti-bacterial coatings

Autores: Nathan Jourdainne, Dimitri Mercier, Bruna Costa, Filipa Campos, Claudia Monteiro, Natália Costa, M. Cristina L. Martins, Pascal Thébault
Publicado en: Colloids and Surfaces B: Biointerfaces, Edición 252, 2025, Página(s) 114679, ISSN 0927-7765
Editor: Elsevier BV
DOI: 10.1016/j.colsurfb.2025.114679

Peptide-based self-assembled monolayers (SAMs): what peptides can do for SAMs and vice versa

Autores: Carlos Redondo-Gómez, Paula Parreira, M. Cristina L. Martins, and Helena S. Azevedo
Publicado en: Chemical Society Reviews, Edición "2024, ""Celebrating the scientific accomplishments of RSC Fellows""", 2024, ISSN 1460-4744
Editor: Royal Society of Chemistry
DOI: 10.1039/d3cs00921a

Bioengineered hyaluronan hydrogels for the delivery of molecular and cellular therapies

Autores: Joana Silva, Helena S. Azevedo
Publicado en: Advanced Therapeutics, 2023, ISSN 2366-3987
Editor: John Wiley & Sons, Inc.
DOI: 10.1002/adtp.202300182

Phage Display Identified Peptide with Selectivity for Human Osteoarthritic Chondrocytes

Autores: Ivone M. Martins, Raphaël F. Canadas, Hélder Pereira, Joana Azeredo, Rui L. Reis, Joaquim M. Oliveira, Helena S. Azevedo
Publicado en: Advanced Therapeutics, 2023, ISSN 2366-3987
Editor: John Wiley & Sons, Inc.
DOI: 10.1002/adtp.202300263

Norbornene-chitosan nanoparticles with and without a conjugated VEGF-peptide analog to promote vascularization

Autores: Pedro M. Alves, Diana R. Fonseca, Sílvia J. Bidarra, Ana Gomes, Paula Gomes, Cristina C. Barrias, M. Cristina L. Martins
Publicado en: Materials Today Chemistry, 2024, ISSN 2468-5194
Editor: Science Direct, Elsevier
DOI: 10.1016/j.mtchem.2024.101942

Engineering resveratrol-loaded chitosan nanoparticles for potential use against Helicobacter pylori infection

Autores: Larissa Spósito, Diana Fonseca, Suzana Gonçalves Carvalho, Rafael Miguel Sábio, Gabriel Davi Marena, Taís Maria Bauab, Andréia Bagliotti Meneguin, Paula Parreira, M. Cristina L. Martins, Marlus Chorilli
Publicado en: European Journal of Pharmaceutics and Biopharmaceutics, Edición 199, 2024, Página(s) 114280, ISSN 0939-6411
Editor: Elsevier BV
DOI: 10.1016/j.ejpb.2024.114280

Validation of Selective Capture of Fimbriated Uropathogenic <i>Escherichia coli</i> by a Label-free Engineering Detection System Using Mannosylated Surfaces

Autores: Leila Mousavifar; Paula Parreira; Alexis Taponard; Vanessa C. D. Graça; M. Cristina L. Martins; René Roy
Publicado en: ACS Applied Bio Materials, 2022, ISSN 2576-6422
Editor: American Chemical Society
DOI: 10.1021/acsabm.2c00838

Norbornene-chitosan spray-dried microspheres for peptide conjugation using thiol-ene “photoclick” chemistry

Autores: Pedro M. Alves; Diana R. Fonseca; Rúben F. Pereira; Berta N. Estevinho; Cátia Teixeira; Paula Gomes; M. Cristina L. Martins
Publicado en: Biomecánica, 2022, ISSN 1885-9518
Editor: Sociedad Ibérica de Biomecánica y Biomateriales

"One-Pot Microfluidics to Engineer Chitosan Nanoparticles Conjugated with Antimicrobial Peptides Using “Photoclick” Chemistry: Validation Using the Gastric Bacterium Helicobacter pylori"""

Autores: Diana R Fonseca, Pedro M. Alves, Estrela Neto, Beatriz Custódio, Sofia Guimarães, Duarte Moura, Francesca Annis, Marco Martins, Ana Gomes, Cátia Teixeira, Paula Gomes, Rúben F. Pereira, Paulo Freitas, Paula Parreira, and M. Cristina L. Martins
Publicado en: ACS Applied Materials & Interfaces, 2024, ISSN 1944-8244
Editor: American Chemical Society
DOI: 10.1021/acsami.3c18772

Chemical engineering of zein with polyethylene glycol and Angiopep-2 to manufacture a brain-targeted docetaxel nanomedicine for glioblastoma treatment

Autores: Seem Awad, Marco Araújo, Paulo Faria, Bruno Sarmento, Cláudia Martins
Publicado en: Drug Delivery and Translational Research, 2024, ISSN 2190-393X
Editor: Springer Pub. Co.,
DOI: 10.1007/s13346-024-01659-x

Dhvar5-chitosan nanogels and their potential to improve antibiotics activity

Autores: B. Costa, P.M. Alves, D.R. Fonseca, F. Campos, A.C. Monteiro, H. Shahrour, A. Gomes, F. Costa, P. Gomes, G. Martínez-de-Tejada, C. Monteiro, M.C.L. Martins
Publicado en: International Journal of Biological Macromolecules, Edición 277, 2024, Página(s) 134059, ISSN 0141-8130
Editor: Elsevier BV
DOI: 10.1016/j.ijbiomac.2024.134059