Straightening training, research and innovation capacities in the valorization of bio-renewable resource

Deliverables

Websites, patent fillings, videos etc. (3)

Creation of the project brand and logo

We envision that the dissemination and exploitation results will be achieved through the engagement activities presented in Section 22

Brochure and flyer development

Communication will be done through the project website promotional brochure and flyer press releases or newsletters presented in Section 22

Website launch

We envision that the dissemination and exploitation results will be achieved through the engagement activities presented in Section 22

Documents, reports (2)

For all KPIs - Impact assessment in the 3-year period before Biomass4Synthons

The impact assessment will be done at the outset of the project

KPIs discrimination for Biomass4Synthons

The KPIs will be carefully examinated with the Consortium members and an ultimate list of these KPIs will be assembled at M2

Publications

Peer reviewed articles (20)

Biorefinery via Achmatowicz Rearrangement: Synthesis of Pentane‐1,2,5‐triol from Furfuryl Alcohol

Author(s): Svilen P. Simeonov, Martin A. Ravutsov, Marko D. Mihovilovic
Published in: ChemSusChem, 12/12, 2019, Page(s) 2748-2754, ISSN 1864-5631
Publisher: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/cssc.201900601

One-Pot Transformation of Salicylaldehydes to Spiroepoxydienones via the Adler–Becker Reaction in a Continuous Flow

Author(s): Andreia A. Rosatella* and Carlos A. M. Afonso*
Published in: ACS Omega, 2022, Page(s) 11570–11577, ISSN 2470-1343
Publisher: ACS Publications
DOI: 10.1021/acsomega.1c05559

Aqueous-Phase Hydrogenation of Levulinic Acid Using Formic Acid as a Sustainable Reducing Agent Over Pt Catalysts Supported on Mesoporous Zirconia

Author(s): M. Al-Naji, M. Popova, Z. Chen, N. Wilde, R. Gläser
Published in: ACS Sustainable Chemistry & Engineering, 8/1, 2019, Page(s) 393-402, ISSN 2168-0485
Publisher: American Chemical Society
DOI: 10.1021/acssuschemeng.9b05546

(1R,4S,5S)-5-((3-Hydroxypropyl)amino)-4-((1-methyl-1H-tetrazol-5-yl)thio)cyclopent-2-en-1-ol

Author(s): Milene Fortunato, Filipa Siopa, Carlos Afonso
Published in: Molbank, 2021/2, 2021, Page(s) M1199, ISSN 1422-8599
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/m1199

Functionalized Cyclopentenones and an Oxime Ether as Antimicrobial Agents

Author(s): Rafael F. A. Gomes; Vera M. S. Isca; Vera M. S. Isca; Késsia Andrade; Patrícia Rijo; Patrícia Rijo; Carlos A. M. Afonso
Published in: Chemmedchem, 2, 2021, Page(s) 2781– 2785, ISSN 1860-7179
Publisher: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/cmdc.202100369

CO2 Adsorption on Modified Mesoporous Silicas: The Role of the Adsorption Sites.

Author(s): Martin Ravutsov; Yavor Mitrev; Pavletta Shestakova; Hristina Lazarova; Svilen P. Simeonov; Margarita Popova
Published in: Volume 11, 1, 2021, Page(s) 2831, ISSN 2079-4991
Publisher: MDPI
DOI: 10.3390/nano11112831

Achmatowicz rearrangement enables hydrogenolysis-free gas-phase synthesis of pentane-1,2,5-triol from furfuryl alcohol

Author(s): Svilen P. Simeonov, Hristina I. Lazarova, Maya K. Marinova, Margarita D. Popova
Published in: Green Chemistry, 21/20, 2019, Page(s) 5657-5664, ISSN 1463-9262
Publisher: Royal Society of Chemistry
DOI: 10.1039/c9gc02888a

Chitin-glucan complex – Based biopolymeric structures using biocompatible ionic liquids

Author(s): Inês C. Ferreira, Diana Araújo, Pierre Voisin, Vítor D. Alves, Andreia A. Rosatella, Carlos A.M. Afonso, Filomena Freitas, Luísa A. Neves
Published in: Carbohydrate Polymers, 247, 2020, Page(s) 116679, ISSN 0144-8617
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.carbpol.2020.116679

Preparation of Thioaminals in Water

Author(s): Lídia A. S. Cavaca; Rafael F. A. Gomes; Carlos A. M. Afonso
Published in: Molecules; Volume 27; Issue 5; Pages: 1673, 4, 2022, Page(s) 1673, ISSN 1420-3049
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules27051673

Site-Selective C–H Functionalization of Arenes Enabled by Noncovalent Interactions

Author(s): Adolfo Fernández-Figueiras, Martin A. Ravutsov, and Svilen P. Simeonov*
Published in: ACS Omega, 2022, Page(s) 6439–6448, ISSN 2470-1343
Publisher: ACS Publications
DOI: 10.1021/acsomega.1c05830

Recent Advances on Diels-Alder-Driven Preparation of Bio-Based Aromatics.

Author(s): João M. J. M. Ravasco; Rafael F. A. Gomes
Published in: Chemsuschem, 2, 2021, Page(s) 3047–305, ISSN 1864-5631
Publisher: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/cssc.202100813

Direct Conversion of Activated 5-Hydroxymethylfurfural into δ-Lactone-Fused Cyclopentenones

Author(s): Rafael F. A. Gomes, Jaime A. S. Coelho, Carlos A. M. Afonso
Published in: ChemSusChem, 12/2, 2019, Page(s) 420-425, ISSN 1864-5631
Publisher: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/cssc.201802537

Reactive Dimerization of an N-Heterocyclic Plumbylene: C−H Activation with Pb II

Author(s): Robin Guthardt, Jan Oetzel, Julia I. Schweizer, Clemens Bruhn, Robert Langer, Martin Maurer, Jan Vícha, Pavletta Shestakova, Max C. Holthausen, Ulrich Siemeling
Published in: Angewandte Chemie International Edition, 58/5, 2019, Page(s) 1387-1391, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201811559

Valorization of Oleuropein via Tunable Acid-Promoted Methanolysis

Author(s): Lídia A. S. Cavaca, Catarina A. B. Rodrigues, Svilen P. Simeonov, Rafael F. A. Gomes, Jaime A. S. Coelho, Gustavo P. Romanelli, Angel G. Sathicq, José J. Martínez, Carlos A. M. Afonso
Published in: ChemSusChem, 11/14, 2018, Page(s) 2300-2305, ISSN 1864-5631
Publisher: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/cssc.201800980

Going Beyond the Limits of the Biorenewable Platform: Sodium Dithionite-Promoted Stabilization of 5-Hydroxymethylfurfural

Author(s): Rafael F. A. Gomes, Yavor N. Mitrev, Svilen P. Simeonov, Carlos A. M. Afonso
Published in: ChemSusChem, 11/10, 2018, Page(s) 1612-1616, ISSN 1864-5631
Publisher: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/cssc.201800297

Creating Diversity from Biomass: A Tandem Bio/Metal‐Catalysis towards Chemoselective Synthesis of Densely Substituted Furans

Author(s): João M. J. M. Ravasco, Carlos M. Monteiro, Filipa Siopa, Alexandre F. Trindade, Julie Oble, Giovanni Poli, Svilen P. Simeonov, Carlos A. M. Afonso
Published in: ChemSusChem, 12/20, 2019, Page(s) 4629-4635, ISSN 1864-5631
Publisher: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/cssc.201902051

Tandem Thio-Michael Addition/Remote Lactone Activation of 5-Hydroxymethylfurfural-Derived δ-Lactone-Fused Cyclopentenones

Author(s): Dr. Rafael F. A. Gomes, Joao M. J. M. Ravasco, Késsia H. S. Andrade, Dr. Jaime A. S. Coelho, Prof. Rui Moreira, Rafael Oliveira, Prof. Fátima Nogueira, Prof. Carlos A. M. Afonso
Published in: ChemSusChem, 2022, ISSN 1864-5631
Publisher: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/cssc.202102204

Rediscovering aminal chemistry: copper( ii ) catalysed formation under mild conditions

Author(s): Juliana G. Pereira, João P. M. António, Ricardo Mendonça, Rafael F. A. Gomes, Carlos A. M. Afonso
Published in: Green Chemistry, 22/21, 2020, Page(s) 7484-7490, ISSN 1463-9262
Publisher: Royal Society of Chemistry
DOI: 10.1039/d0gc01977a

Silica-Supported Copper for the Preparation of trans-4,5-Diamino-Cyclopent-2-Enones under Continuous Flow Conditions

Author(s): Rafael F. A. Gomes; Lídia A. S. Cavaca; João Gonçalves; Ruben Ramos; Andreia F. Peixoto; Blanca I. Arias-Serrano; Blanca I. Arias-Serrano; Carlos A. M. Afonso
Published in: ACS Sustainable Chem. Eng., 2, 2021, Page(s) 16038–16043, ISSN 2168-0485
Publisher: American Chemical Society
DOI: 10.1021/acssuschemeng.1c00884

Carboxamides vs. methanimines: Crystal structures, binding interactions, photophysical studies, and biological evaluation of (indazole-5-yl)methanimines as monoamine oxidase B and acetylcholinesterase inhibitors

Author(s): Nikolay T. Tzvetkov, Hans-Georg Stammler, Maya G. Georgieva, Daniela Russo, Immacolata Faraone, Aneliya A. Balacheva, Silvia Hristova, Atanas G. Atanasov, Luigi Milella, Liudmil Antonov, Marcus Gastreich
Published in: European Journal of Medicinal Chemistry, 179, 2019, Page(s) 404-422, ISSN 0223-5234
Publisher: Elsevier BV
DOI: 10.1016/j.ejmech.2019.06.041

Thesis dissertations (1)

Natural inspired small organic molecules for targeting aquaporins as a novel therapeutic approach to pancreatic cancer

Author(s): Jesus, Rita Rodrigues Fernandes de
Published in: 1, 2021
Publisher: Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa