Straightening training, research and innovation capacities in the valorization of bio-renewable resource

Informacje na temat projektu

Biomass4Synthons

Identyfikator umowy o grant: 951996

DOI

10.3030/951996

Projekt został zamknięty

Data podpisania przez KE 30 Czerwca 2020

Data rozpoczęcia 1 Stycznia 2021

Data zakończenia 30 Czerwca 2024

Finansowanie w ramach

• Twinning of research institutions

Koszt całkowity

€ 900 000,00

Wkład UE

€ 900 000,00

Koordynowany przez

Faculdade de Farmácia da Universidade de Lisboa
Portugal

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Documents, reports (10)

Biomass4Synthons Summer Schools

FFUL and IOCCP-BAS will prepare the summer schools.

For all KPIs - Impact assessment in the 3-year period before Biomass4Synthons

The impact assessment will be done at the outset of the project

Report of the industry meeting

Communication will be done through the project website, promotional brochure and flyer, press releases or newsletters, presented in Section 2.2.

Biomass4Synthons Thematic Workshop

We envision that the dissemination and exploitation results will be achieved through the engagement activities presented in Section 2.2

Public awareness movement

Communication will be done through the project website, promotional brochure and flyer, press releases or newsletters, presented in Section 2.2.

Resume of the Project publications

Communication will be done through the project website, promotional brochure and flyer, press releases or newsletters, presented in Section 2.2.

Impact evaluation by the project terminus and estimate the next 3-year period

The impact assessment will be done at the terminus.

"Event ""Knowledge Transfer Zone"" through meetings between enterprises and research institutions"

Biomass4Synthons planned a challenge competition point toward rising entrepreneurial skills over a hands-on and motivating approach. These initiative will embrace students and the research community that together will envision how to take innovation to the market. Experts from the partnering institutions will be invited to provide inspiring lectures and to stimulate brainstorming.

"Event ""The industrial day"" related to flow chemistry applications"

Biomass4Synthons planned a challenge competition point toward rising entrepreneurial skills over a hands-on and motivating approach. These initiative will embrace students and the research community that together will envision how to take innovation to the market. Experts from the partnering institutions will be invited to provide inspiring lectures and to stimulate brainstorming.

KPIs discrimination for Biomass4Synthons

The KPIs will be carefully examinated with the Consortium members and an ultimate list of these KPIs will be assembled at M2

Websites, patent fillings, videos etc. (3)

Creation of the project brand and logo

We envision that the dissemination and exploitation results will be achieved through the engagement activities presented in Section 22

Brochure and flyer development

Communication will be done through the project website promotional brochure and flyer press releases or newsletters presented in Section 22

Website launch

We envision that the dissemination and exploitation results will be achieved through the engagement activities presented in Section 22

Publikacje

Peer reviewed articles (31)

Striving for Uniformity: A Review on Advances and Challenges To Achieve Uniform Polyethylene Glycol

Autorzy: Cláudia Bento, Marianna Katz, Maria M. M. Santos, Carlos A. M. Afonso
Opublikowane w: Organic Process Research & Development, Numer 28, 2024, Strona(/y) 860-890, ISSN 1083-6160
Wydawca: American Chemical Society
DOI: 10.1021/acs.oprd.3c00428

Unlocking the Potential of Bio‐Based Nitrogen‐Rich Furanic Platforms as Biomass Synthons

Autorzy: Rafael F. A. Gomes, Bruno M. F. Gonçalves, Késsia H. S. Andrade, Bárbara B. Sousa, Nuno Maulide, Gonçalo J. L. Bernardes, Carlos A. M. Afonso
Opublikowane w: Angewandte Chemie International Edition, Numer 62, 2023, ISSN 1433-7851
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202304449

A direct Diels–Alder reaction of chitin derived 3-acetamido-5-acetylfuran

Autorzy: Juliana G. Pereira, João M. J. M. Ravasco, João R. Vale, Fausto Queda, Rafael F. A. Gomes
Opublikowane w: Green Chemistry, Numer 24, 2024, Strona(/y) 7131-7136, ISSN 1463-9262
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d2gc00253a

Preparation of Aminals under Continuous Flow Conditions

Autorzy: Rafael F. A. Gomes, Carlos A. M. Afonso
Opublikowane w: Journal of Chemical Education, Numer 100, 2023, Strona(/y) 4728-4733, ISSN 0021-9584
Wydawca: American Chemical Society
DOI: 10.1021/acs.jchemed.3c00306

Upgrading furanic platforms to α-enaminones: tunable continuous flow hydrogenation of bio-based cyclopentenones

Autorzy: Lídia A. S. Cavaca, Jaime A. S. Coelho, Susana D. Lucas, Rui M. S. Loureiro, Rafael F. A. Gomes, Carlos A. M. Afonso
Opublikowane w: Reaction Chemistry & Engineering, Numer 8, 2024, Strona(/y) 482-489, ISSN 2058-9883
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d2re00292b

One-Pot Transformation of Salicylaldehydes to Spiroepoxydienones via the Adler–Becker Reaction in a Continuous Flow

Autorzy: Andreia A. Rosatella* and Carlos A. M. Afonso*
Opublikowane w: ACS Omega, 2022, Strona(/y) 11570–11577, ISSN 2470-1343
Wydawca: ACS Publications
DOI: 10.1021/acsomega.1c05559

(1R,4S,5S)-5-((3-Hydroxypropyl)amino)-4-((1-methyl-1H-tetrazol-5-yl)thio)cyclopent-2-en-1-ol

Autorzy: Milene Fortunato, Filipa Siopa, Carlos Afonso
Opublikowane w: Molbank, Numer 2021/2, 2021, Strona(/y) M1199, ISSN 1422-8599
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/m1199

Orthogonally Protected Diaminocyclopentenones as Synthons: Total Synthesis of (±)-Agelastatin A

Autorzy: Rafael F. A. Gomes, João R. Vale, Juliana G. Pereira, Carlos A. M. Afonso
Opublikowane w: Organic Letters, Numer 25, 2023, Strona(/y) 4188-4192, ISSN 1523-7060
Wydawca: American Chemical Society
DOI: 10.1021/acs.orglett.3c01513

Functionalized Cyclopentenones and an Oxime Ether as Antimicrobial Agents

Autorzy: Rafael F. A. Gomes; Vera M. S. Isca; Vera M. S. Isca; Késsia Andrade; Patrícia Rijo; Patrícia Rijo; Carlos A. M. Afonso
Opublikowane w: Chemmedchem, Numer 2, 2021, Strona(/y) 2781– 2785, ISSN 1860-7179
Wydawca: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/cmdc.202100369

CO2 Adsorption on Modified Mesoporous Silicas: The Role of the Adsorption Sites.

Autorzy: Martin Ravutsov; Yavor Mitrev; Pavletta Shestakova; Hristina Lazarova; Svilen P. Simeonov; Margarita Popova
Opublikowane w: Volume 11, Numer 1, 2021, Strona(/y) 2831, ISSN 2079-4991
Wydawca: MDPI
DOI: 10.3390/nano11112831

C3-Alkylation of furfural derivatives by continuous flow homogeneous catalysis

Autorzy: Grédy Kiala Kinkutu, Catherine Louis, Myriam Roy, Juliette Blanchard, Julie Oble
Opublikowane w: Beilstein Journal of Organic Chemistry, Numer 19, 2023, Strona(/y) 582-592, ISSN 1860-5397
Wydawca: Beilstein-Institut
DOI: 10.3762/bjoc.19.43

High-Pressure Promoted Nazarov-like Electrocyclization Enables Access to <i>trans</i>-4,5-Diamino-cyclopent-2-enones Bearing Electron-Poor Anilines

Autorzy: Lídia A. S. Cavaca, Tiago M. P. Santos, Joao M. J. M. Ravasco, Rafael F. A. Gomes, Carlos A. M. Afonso
Opublikowane w: The Journal of Organic Chemistry, Numer 89, 2024, Strona(/y) 6677-6683, ISSN 0022-3263
Wydawca: American Chemical Society
DOI: 10.1021/acs.joc.3c01040

Ru-Catalyzed Isomerization of Achmatowicz Derivatives: A Sustainable Route to Biorenewables and Bioactive Lactones

Autorzy: Miroslav Dangalov, Adolfo Fernández-Figueiras, Martin A. Ravutsov, Ekaterina Vakarelska, Maya K. Marinova, Nuno R. Candeias, Svilen P. Simeonov
Opublikowane w: ACS Catalysis, Numer 13, 2023, Strona(/y) 1916-1925, ISSN 2155-5435
Wydawca: American Chemical Society
DOI: 10.1021/acscatal.2c04867

From Pyridine to (−)‐Agelastatin A

Autorzy: João R. Vale, Milene A. G. Fortunato, Késsia H. S. Andrade, Ângelo M. R. Rocha, Carlos A. M. Afonso, Filipa Siopa
Opublikowane w: Advanced Synthesis &amp; Catalysis, Numer 365, 2023, Strona(/y) 2240-2247, ISSN 1615-4150
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/adsc.202300560

Preparation of Thioaminals in Water

Autorzy: Lídia A. S. Cavaca; Rafael F. A. Gomes; Carlos A. M. Afonso
Opublikowane w: Molecules; Volume 27; Numer 5; Pages: 1673, Numer 4, 2022, Strona(/y) 1673, ISSN 1420-3049
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules27051673

Site-Selective C–H Functionalization of Arenes Enabled by Noncovalent Interactions

Autorzy: Adolfo Fernández-Figueiras, Martin A. Ravutsov, and Svilen P. Simeonov*
Opublikowane w: ACS Omega, 2022, Strona(/y) 6439–6448, ISSN 2470-1343
Wydawca: ACS Publications
DOI: 10.1021/acsomega.1c05830

Recent Advances on Diels-Alder-Driven Preparation of Bio-Based Aromatics.

Autorzy: João M. J. M. Ravasco; Rafael F. A. Gomes
Opublikowane w: Chemsuschem, Numer 2, 2021, Strona(/y) 3047–305, ISSN 1864-5631
Wydawca: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/cssc.202100813

Sources, sustainability and directions in the chemical synthesis of δ-aminolevulinic acid

Autorzy: Martin A. Ravutsov, Maya M. Marinova, Atanas Kurutos, Svilen P. Simeonov
Opublikowane w: Sustainable Chemistry and Pharmacy, Numer 38, 2024, Strona(/y) 101491, ISSN 2352-5541
Wydawca: MDPI
DOI: 10.1016/j.scp.2024.101491

4-Ketovalero lactone (KVL): A gateway molecule for diversification of the furanic platform

Autorzy: Raquel M. Durão, Maya K. Marinova, Martin A. Ravutsov, Svilen P. Simeonov
Opublikowane w: Sustainable Chemistry and Pharmacy, Numer 39, 2024, Strona(/y) 101553, ISSN 2352-5541
Wydawca: Elsevier
DOI: 10.1016/j.scp.2024.101553

Cu‐Catalyzed Tandem Oxidation‐Intramolecular Cannizzaro Reaction of Biorenewables and Bioactive Molecules

Autorzy: Hristo Petkov, Martin A. Ravutsov, Manuel J. Verganista, Yavor N. Mitrev, Nuno R. Candeias, Svilen P. Simeonov
Opublikowane w: ChemSusChem, Numer 17, 2024, ISSN 1864-5631
Wydawca: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/cssc.202400013

Functionalized Cyclopentenones with Low Electrophilic Character as Anticancer Agents

Autorzy: Késsia H. S. Andrade, Jaime A. S. Coelho, Raquel Frade, Ana M. Madureira, João P. M. Nunes, Stephen Caddick, Rafael F. A. Gomes, Carlos A. M. Afonso
Opublikowane w: ChemMedChem, Numer 18, 2023, ISSN 1860-7179
Wydawca: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/cmdc.202300104

2-Azabicyclo[3.2.1]octane scaffold: synthesis and applications

Autorzy: Mariana Crespo Monteiro, João Rafael Vale, Filipa Siopa
Opublikowane w: Organic &amp; Biomolecular Chemistry, Numer 22, 2024, Strona(/y) 2902-2915, ISSN 1477-0520
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d4ob00199k

Amidoalkyl Naphthols as Important Bioactive Substances and Building Blocks: A Review on the Current Catalytic Mannich-Type Synthetic Approaches

Autorzy: Hristo Petkov, Svilen P. Simeonov
Opublikowane w: Applied Sciences, Numer 13, 2023, Strona(/y) 6616, ISSN 2076-3417
Wydawca: MDPI
DOI: 10.3390/app13116616

Semi-continuous and continuous processes for enantiomeric separation

Autorzy: Marina Ciriani, Rudi Oliveira, Carlos A. M. Afonso
Opublikowane w: Green Chemistry, Numer 24, 2024, Strona(/y) 4328-4362, ISSN 1463-9262
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d1gc03668h

Base-promoted direct amidation of esters: beyond the current scope and practical applications

Autorzy: Ivaylo Slavchev, Jas. S. Ward, Kari Rissanen, Georgi M. Dobrikov, Svilen Simeonov
Opublikowane w: RSC Advances, Numer 12, 2024, Strona(/y) 20555-20562, ISSN 2046-2069
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d2ra03524c

Biorenewable Oxypropylated Pentane-1,2,5-triol as a Source for Incorporation in Rigid Polyurethane Foams

Autorzy: Georgy Grancharov, Mariya-Desislava Atanasova, Radostina Kalinova, Pencho Tuleshkov, Petar D. Petrov, Maya K. Marinova, Martin A. Ravutsov, Svilen P. Simeonov
Opublikowane w: Polymers, Numer 15, 2023, Strona(/y) 4148, ISSN 2073-4360
Wydawca: MDPI
DOI: 10.3390/polym15204148

Tandem Thio-Michael Addition/Remote Lactone Activation of 5-Hydroxymethylfurfural-Derived δ-Lactone-Fused Cyclopentenones

Autorzy: Dr. Rafael F. A. Gomes, Joao M. J. M. Ravasco, Késsia H. S. Andrade, Dr. Jaime A. S. Coelho, Prof. Rui Moreira, Rafael Oliveira, Prof. Fátima Nogueira, Prof. Carlos A. M. Afonso
Opublikowane w: ChemSusChem, 2022, ISSN 1864-5631
Wydawca: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/cssc.202102204

Modular synthesis of 2-furyl carbinols from 3-benzyldimethylsilylfurfural platforms relying on oxygen-assisted C–Si bond functionalization

Autorzy: Sebastien Curpanen, Per Reichert, Gabriele Lupidi, Giovanni Poli, Julie Oble, Alejandro Perez-Luna
Opublikowane w: Beilstein Journal of Organic Chemistry, Numer 18, 2022, Strona(/y) 1256-1263, ISSN 1860-5397
Wydawca: Beilstein-Institut
DOI: 10.3762/bjoc.18.131

Functional Nanogel from Natural Substances for Delivery of Doxorubicin

Autorzy: Katya Kamenova, Lyubomira Radeva, Krassimira Yoncheva, Filip Ublekov, Martin A. Ravutsov, Maya K. Marinova, Svilen P. Simeonov, Aleksander Forys, Barbara Trzebicka, Petar D. Petrov
Opublikowane w: Polymers, Numer 14, 2024, Strona(/y) 3694, ISSN 2073-4360
Wydawca: MDPI
DOI: 10.3390/polym14173694

Sustainable synthesis of nitrogen-rich aromatics from chitin: Opportunities and challenges

Autorzy: Nicholas Bossons, Rafael F.A. Gomes
Opublikowane w: Current Opinion in Green and Sustainable Chemistry, Numer 49, 2024, Strona(/y) 100961, ISSN 2452-2236
Wydawca: Elsevier
DOI: 10.1016/j.cogsc.2024.100961

Silica-Supported Copper for the Preparation of trans-4,5-Diamino-Cyclopent-2-Enones under Continuous Flow Conditions

Autorzy: Rafael F. A. Gomes; Lídia A. S. Cavaca; João Gonçalves; Ruben Ramos; Andreia F. Peixoto; Blanca I. Arias-Serrano; Blanca I. Arias-Serrano; Carlos A. M. Afonso
Opublikowane w: ACS Sustainable Chem. Eng., Numer 2, 2021, Strona(/y) 16038–16043, ISSN 2168-0485
Wydawca: American Chemical Society
DOI: 10.1021/acssuschemeng.1c00884

Thesis and dissertations (3)

Photochemical Reactions of Acylsilanes Towards the Construction of Carbon-Carbon Bonds

Autorzy: João R. Vale
Opublikowane w: 2023, ISBN 978-952-03-2773-6
Wydawca: Tampere University

Natural inspired small organic molecules for targeting aquaporins as a novel therapeutic approach to pancreatic cancer

Autorzy: Jesus, Rita Rodrigues Fernandes de
Opublikowane w: Numer 1, 2021
Wydawca: Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa

Electrochemical oxidation of abietanes

Autorzy: Martins, Inês Alexandra de Sá
Opublikowane w: Numer 2021/09, 2021
Wydawca: University of Lisnon