MARA-BASED INDUSTRIAL LOW-COST IDENTIFICATION ASSAYS

Informazioni relative al progetto

MARILIA

ID dell’accordo di sovvenzione: 952110

DOI 10.3030/952110

Progetto chiuso

Data della firma CE 6 Maggio 2020

Data di avvio 1 Settembre 2020

Data di completamento 28 Febbraio 2023

Finanziato da

• EXCELLENT SCIENCE - Future and Emerging Technologies (FET)

Costo totale € 2 000 741,25

Contributo UE € 1 999 972,50

Coordinato da

AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH
Austria

Risultati finali

Documents, reports (7)

Communication and dissemination plan

A document presenting the elaborated Communication and Dissemination Strategy along with an action plan

Report on MD trajectories

A report summarizing the results of MD simulations for improving the activity of the split form enzyme

Communication toolkit

A report will be prepared to define the communication tools to be used within MARILIA project

Report on docking calculations

A report summarizing docking calculations used to figure out the most beneficial peroxidase splitting

Report on QM/MM calculations

A report summarizing the results of QMMM calculations for finetuning the enzyme activity in the split form

Report on the Role of Actors and Design of Stakeholder Framework

A report presenting the Role of Actors and the Design of Stakeholder Framework based on literature research expertinterviews and surveys and serving as a base for the technical developments of the MARILIA product

Description of the use cases and test experiments

A report to present a comprehensive set of use cases for the product usercentered stakeholders objectives roles and levels of interaction with the overall platform etc The use cases will include the integration of the product in the customers processes and serve as a framework to further derive test experiments

Open Research Data Pilot (1)

Data Management Plan, DMP

Data Management Plan will be prepared in compliance with EC rules and will cover the handling of data during and after the project lifetime the rules for collecting processing using and generating data and the standards to be applied It will state the base for partners participation in the Pilot on Open Research Data in Horizon 2020

Websites, patent fillings, videos etc. (1)

MARILIA project website

The MARILIA website will the main communication medium gathering all relevant information regarding the project and its participants

Other (1)

Updated version of Adenita software

The Adenita software will be extended with features in data handling, interactive modelling, and visualizing the structures.

Pubblicazioni

Peer reviewed articles (6)

Analyzing Criteria Affecting the Functionality of G-Quadruplex-Based DNA Aptazymes as Colorimetric Biosensors and Development of Quinine-Binding Aptazymes

Autori: Yasaman Ahmadi, Regina Soldo, Krista Rathammer, Laura Eibler, and Ivan Barišić
Pubblicato in: Analytical Chemistry, Numero 93, 2021, Pagina/e 5161-5169, ISSN 0003-2700
Editore: American Chemical Society
DOI: 10.1021/acs.analchem.0c05052

Effect of N-glycosylation on horseradish peroxidase structural and dynamical properties

Autori: Sanja Škulj; Antun Barišić; Natalie Mutter; Oliver Spadiut; Ivan Barisic, and Branimir Bertoša
Pubblicato in: Computational and Structural Biotechnology Journal, 2022, ISSN 2001-0370
Editore: Elsevier
DOI: 10.1016/j.csbj.2022.06.008

HIGHLY SELECTIVE PREPARATION OF N-TERMINUS HORSERADISH PEROXIDASE-DNA CONJUGATE WITH FULLY RETAINED ENZYMATIC ACTIVITY: HRP-DNA STRUCTURE – ACTIVITY RELATION

Autori: Željka Ban, Antun Barišić,Ivo Crnolatac, Saša Kazazić, Sanja Škulj, Filippo Savini Branimir Bertoša, Ivan Barišić and Ivo Piantanida
Pubblicato in: Enzyme and Microbial Technology, 2023, ISSN 1879-0909
Editore: Elsevier
DOI: 10.1016/j.enzmictec.2023.110257

CATANA: AN ONLINE MODELLING ENVIRONMENT FOR PROTEINS AND NUCLEIC NANOSTRUCTURES

Autori: David Kuťák, Lucas Melo, Fabian Schroeder, Zoe Jelic-Matošević, Natalie Mutter, Branimir Bertoša, Ivan Barišić
Pubblicato in: Nucleic Acids Research, 2022, ISSN 1362-4962
Editore: Oxford University Press
DOI: 10.1093/nar/gkac350

Unified Nanotechnology Format: One Way to Store Them All

Autori: David Kuťák, Erik Poppleton, Haichao Miao, Petr Šulc, Ivan Barišić
Pubblicato in: Molecules, 2021, Pagina/e Dec 23;27(1):63, ISSN 1420-3049
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules27010063

Vivern A Virtual Environment for Multiscale Visualization and Modeling of DNA Nanostructures.

Autori: David Kutak; Matías Nicolás Selzer; Jan Byška; María Luján Ganuza; Ivan Barišić; Barbora Kozlíková; Haichao Miao
Pubblicato in: IEEE TRANSACTIONS ON VISUALIZATION AND COMPUTER GRAPHICS, 2021, ISSN 1077-2626
Editore: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tvcg.2021.3106328

Other (2)

INFLUENCE OF N-GLYCOSYLATION ON HORSERADISHPEROXIDASE STABILIZATION

Autori: Sanja Škulj, Antun Barišić, Zoe Jelić Matošević, Branimir Bertoša
Pubblicato in: 2021
Editore: 27th CROATIAN MEETING OF CHEMISTS AND CHEMICAL ENGINEERS

COMPUTATIONAL STUDY OF THE GLYCOSYLATED HRP ENZYMEUSED IN PATHOGEN DETECTION

Autori: Antun Barišić, Sanja Škulj, Zoe Jelić Matošević, Branimir Bertoša
Pubblicato in: 2021
Editore: 27th CROATIAN MEETING OF CHEMISTS AND CHEMICAL ENGINEERS