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CORDIS - Resultados de investigaciones de la UE
CORDIS

Directing the immune response through designed nanomaterials

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

First report on relationship between NP coating, biomolecular corona and complement activation (se abrirá en una nueva ventana)

First report describing the relationship between nanoparticle coating, biomolecular corona, and complement activation

Report on the effects of loaded NPs and nanovaccines on xenograft tumor growth (se abrirá en una nueva ventana)

Report on the effects of NPs and nanovaccines on xenograft tumor growth

Final report on interactions of NPs with immune cells and molecules (se abrirá en una nueva ventana)

Final report on interactions of NP with immune cells and molecules

Report on effects of selected NPs in in vivo tumor models (se abrirá en una nueva ventana)
Supervisory Board of the Network (se abrirá en una nueva ventana)

Document establishing the supervisory board and defining the way of working

Report on the synthesis of advanced polymers for NP coating (se abrirá en una nueva ventana)

Report on the synthesis of advanced polymers and lipids for NP coating

Report on nanovaccine localization in the mouse immune system (se abrirá en una nueva ventana)
Report on the toxicity profiling of nanovaccines (se abrirá en una nueva ventana)
Reports on dissemination activities (se abrirá en una nueva ventana)

Reports on dissemination activities (RDA) (web, newsletter, social)-RDA1:month 24-RDA2:month 48

Report on humoral and cellular immunity induced by nanovaccines after the first immunization campaign (se abrirá en una nueva ventana)

Report on humoral and cellular immunity induced by nanovaccines in vitro and after the first immunization campaign

Report on the preparation of second generation optimized NPs (se abrirá en una nueva ventana)

Report on preparation of second generation (optimized) NPs

Report on preparation of first generation NPs and protocol selecting NPs monodispersed in biological media (se abrirá en una nueva ventana)

Report on the preparation of first generation NPs and protocol for a standardized procedure for selecting NPs which remain monodispersed in relevant biological media

First report on interactions of NPs with immune cells and molecules (se abrirá en una nueva ventana)

First report on interactions of NP with immune cells and molecules

Report on the development of monoclonal antibodies for selected corona proteins (se abrirá en una nueva ventana)

Report on the development of monoclonal antibodies against selected corona proteins and specie-specific immune assays

Report on preparation of NPs functionalized with antigens and antigen mimics (se abrirá en una nueva ventana)
Report on the effects of nanovaccines on lung metastases (se abrirá en una nueva ventana)

Report on the effects of loaded NPs and nanovaccines on lung metastases

ESRs recruited (se abrirá en una nueva ventana)
Summer schools (se abrirá en una nueva ventana)

Summer schools (SS) schedule:-SS1: month 8-SS2: month 20-SS3:month 32

Compilation of a structure-activity relationship chart summarizing how the various NP coatings affect the immune response (with WP1) (se abrirá en una nueva ventana)

Compilation of a structure-activity relationship chart summarizing how the various NP coatings affect the immune response (together with WP2)

Protocols for the preparation and characterization of collectin analogues (se abrirá en una nueva ventana)

Protocols for the preparation and characterization of collectin analogues and derivatives

Exchange of expertise between academia and industry, including spin-off generation (se abrirá en una nueva ventana)

Exchange of expertise between academia and industry, including spin-off generation (EXC)-EXC1:month 24-EXC 2:month 48

Technical and transferable skills workshops (se abrirá en una nueva ventana)

Technical and transferable skills workshops (WS).Workshops schedule:-WS1:month 12-WS2:month 18-WS3:month 24-WS4:month 30-WS5:Month 36

Protocol for cancer nanovaccine candidates and administration routes: animal experimentation ethics committee approval (se abrirá en una nueva ventana)

Approval from animal experimentation ethics committee, identification of an objective selection protocol for promising cancer nanotherapeutics and nanovaccine candidates, and of prospective administration routes

Protocol for endotoxin profiling on NP formulations (se abrirá en una nueva ventana)

Advanced protocol for endotoxin profiling on nanoparticle based formulations

Publications in the open access primary literature (se abrirá en una nueva ventana)

Publications in the open access (POA) primary literaturePOA1:month 24POA2:month 48

International conference attendance (se abrirá en una nueva ventana)

International conference (IC) attendance schedule:IC1:month 24IC2:month 48

Website (se abrirá en una nueva ventana)
Final conference (se abrirá en una nueva ventana)

two-day conference to showcase the research area and the achievements of thenetwork, also accessible to the general public

Publicaciones

Polymer functionalization of inorganic nanoparticles for biomedical applications (se abrirá en una nueva ventana)

Autores: Tobias Komsthöft, Giovanni Bovone, Stéphane Bernhard, Mark W Tibbitt
Publicado en: Current Opinion in Chemical Engineering, Edición 37, 2022, Página(s) 100849, ISSN 2211-3398
Editor: Elsevier BV
DOI: 10.1016/j.coche.2022.100849

Non‐Fouling Multi‐Azide Polyoxazoline Brush‐co‐Polymers for Sensing Applications (se abrirá en una nueva ventana)

Autores: Tobias Komsthöft, Niccolò Bartalucci, Mark W. Tibbitt, Samuele Tosatti, Stefan Zürcher
Publicado en: Advanced Materials Interfaces, Edición 11, 2024, ISSN 2196-7350
Editor: Advanced Materials Interfaces published by Wiley-VCH GmbH
DOI: 10.1002/admi.202400322

Detection of Tumor‐Associated Autoantibodies in the Sera of Pancreatic Cancer Patients Using Engineered MUC1 Glycopeptide Nanoparticle Probes (se abrirá en una nueva ventana)

Autores: Francisco Corzana, Alicia Asín, Ander Eguskiza, Elisa De Tomi, Alfonso Martín‐Carnicero, María P. Martínez‐Moral, Vincenzo Mangini, Francesco Papi, Carmen Bretón, Paula Oroz, Laura Lagartera, Ester Jiménez‐Moreno, Alberto Avenoza, Jesús H. Busto, Cristina Nativi, Juan L. Asensio, Ramón Hurtado‐Guerrero, Jesús M. Peregrina, Giovanni Malerba, Alfredo Martínez, Roberto Fiammengo
Publicado en: Angewandte Chemie, Edición 136, 2024, ISSN 0044-8249
Editor: WILEY-VCH GmbH
DOI: 10.1002/ange.202407131

A brief history of long circulating nanoparticles (se abrirá en una nueva ventana)

Autores: H.B. Haroon, A.C. Hunter, Z.S. Farhangrazi, S.M. Moghimi
Publicado en: Advanced Drug Delivery Reviews, Edición Volume 188, 2022, Página(s) 114396, ISSN 0169-409X
Editor: Elsevier BV
DOI: 10.1016/j.addr.2022.114396

Preclinical Efficacy of Cabazitaxel Loaded Poly(2-alkyl cyanoacrylate) Nanoparticle Variants (se abrirá en una nueva ventana)

Autores: Remya Valsalakumari, Abhilash Pandya, Lina Prasmickaite, Audun Kvalvaag, Anne Myrann, Andreas Åslund, Marianne Kjos, Cristina Fontecha-Cuenca, Hajira Haroon, Ana Ribeiro, Jutta Horejs-Hoeck, S Moein Moghimi, Ýrr Mørch, Tore Skotland, Kirsten Sandvig, Gunhild Mælandsmo, Tore Geir Iversen
Publicado en: International Journal of Nanomedicine, Edición Volume 19, 2024, Página(s) 3009-3029, ISSN 1178-2013
Editor: Dove Medical Press
DOI: 10.2147/ijn.s450283

Nanometer- and angstrom-scale characteristics that modulate complement responses to nanoparticles (se abrirá en una nueva ventana)

Autores: S.M. Moghimi, H.B. Haroon, A. Yaghmur, D. Simberg, P.N. Trohopoulos
Publicado en: Journal of Controlled Release, Edición Volume 351, 2022, Página(s) 432-443, ISSN 0168-3659
Editor: Elsevier BV
DOI: 10.1016/j.jconrel.2022.09.039

Essential protocols for decoding the composition and the functional effects of the nanoparticle protein corona (se abrirá en una nueva ventana)

Autores: Maria Morbidelli, Emanuele Papini, Regina Tavano
Publicado en: Frontiers in Nanotechnology, Edición 6, 2024, ISSN 2673-3013
Editor: Frontiers Media SA
DOI: 10.3389/fnano.2024.1500567

Structure-Guided Approach for the Development of MUC1-Glycopeptide-Based Cancer Vaccines with Predictable Responses (se abrirá en una nueva ventana)

Autores: Iris A. Bermejo, Ana Guerreiro, Ander Eguskiza, Nuria Martínez-Sáez, Foivos S. Lazaris, Alicia Asín, Víctor J. Somovilla, Ismael Compañón, Tom K. Raju, Srdan Tadic, Pablo Garrido, Josune García-Sanmartín, Vincenzo Mangini, Ana S. Grosso, Filipa Marcelo, Alberto Avenoza, Jesús H. Busto, Fayna García-Martín, Ramón Hurtado-Guerrero, Jesús M. Peregrina, Gonçalo J. L. Bernardes, Alfredo M
Publicado en: JACS Au, Edición 4, 2024, Página(s) 150-163, ISSN 2691-3704
Editor: American Chemical Society
DOI: 10.1021/jacsau.3c00587

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