ROles of ePitranscriptomic in diseasES

Project description

Insight into the role of mRNA modifications

Emerging evidence indicates that like chromatin, mRNA carries certain covalent modifications. Although their role is still being investigated, it seems that these modifications determine the levels, translatability and subcellular compartmentalisation of target mRNAs with profound consequences for cell processes. The EU-funded ROPES project will focus on epitranscriptomics as the missing link between genomic variability and cellular phenotype. Results will help delineate disease mechanisms, identify novel biomarkers and develop innovative therapies. By training early-stage researchers, ROPES aims to establish a European framework that can accelerate research efforts and industrial applications in the promising field of epitranscriptomics.

Fields of science

• natural sciences › biological sciences › genetics › DNA
• medical and health sciences › medical biotechnology › cells technologies › stem cells
• medical and health sciences › clinical medicine › oncology
• natural sciences › biological sciences › genetics › RNA

Programme(s)

• H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme
• H2020-EU.1.3.1. - Fostering new skills by means of excellent initial training of researchers

Topic(s)

• MSCA-ITN-2020 - Innovative Training Networks

Call for proposal

H2020-MSCA-ITN-2020

See other projects for this call

Funding Scheme

MSCA-ITN - Marie Skłodowska-Curie Innovative Training Networks (ITN)

Coordinator

UNIVERSITA DEGLI STUDI DI TRENTO

Net EU contribution

€ 522 999,36

Address

Via Calepina 14
38122 Trento
Italy

Region

Nord-Est › Provincia Autonoma di Trento › Trento

Activity type

Higher or Secondary Education Establishments

Links

Other funding

€ 0,00

Participants (10)

MEDIZINISCHE UNIVERSITAET WIEN

Austria

Net EU contribution

€ 264 207,24

Address

Spitalgasse 23
1090 Wien

Region

Wien › Wien

Activity type

Higher or Secondary Education Establishments

Links

Other funding

€ 0,00

UNIVERSITE DE LAUSANNE

Switzerland

Net EU contribution

€ 281 276,64

Address

Quartier Unil-centre Bâtiment Unicentre
1015 Lausanne

Region

Schweiz/Suisse/Svizzera › Région lémanique › Vaud

Activity type

Higher or Secondary Education Establishments

Links

Other funding

€ 0,00

MIEDZYNARODOWY INSTYTUT BIOLOGII MOLEKULARNEJ I KOMORKOWEJ W WARSZAWIE

Poland

Net EU contribution

€ 227 478,60

Address

Ul. Ksiecia Trojdena 4
02109 Warszawa

Region

Makroregion województwo mazowieckie › Warszawski stołeczny › Miasto Warszawa

Activity type

Research Organisations

Links

Other funding

€ 0,00

UMEA UNIVERSITET

Sweden

Net EU contribution

€ 281 982,96

Address

Universitetomradet
901 87 Umea

Region

Norra Sverige › Övre Norrland › Västerbottens län

Activity type

Higher or Secondary Education Establishments

Links

Other funding

€ 0,00

DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG

Germany

Net EU contribution

€ 252 788,40

Address

Im Neuenheimer Feld 280
69120 Heidelberg

Region

Baden-Württemberg › Karlsruhe › Heidelberg, Stadtkreis

Activity type

Research Organisations

Links

Other funding

€ 0,00

CONSIGLIO NAZIONALE DELLE RICERCHE

Italy

Net EU contribution

€ 261 499,68

Address

Piazzale Aldo Moro 7
00185 Roma

Region

Centro (IT) › Lazio › Roma

Activity type

Research Organisations

Links

Other funding

€ 0,00

FUNDACIO CENTRE DE REGULACIO GENOMICA

Spain

Net EU contribution

€ 250 904,88

Address

Carrer Doctor Aiguader 88
08003 Barcelona

Region

Este › Cataluña › Barcelona

Activity type

Research Organisations

Links

Other funding

€ 0,00

Masarykova univerzita

Czechia

Net EU contribution

€ 234 871,56

Address

Zerotinovo Namesti 9
601 77 Brno

Region

Jihovýchod › Jihomoravský kraj

Activity type

Higher or Secondary Education Establishments

Links

Other funding

€ 0,00

IMMAGINA BIOTECHNOLOGY SRL

Italy

Net EU contribution

€ 261 499,68

Address

Via Sommarive 18
38123 Trento

SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes

Region

Nord-Est › Provincia Autonoma di Trento › Trento

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

Links

Other funding

€ 0,00

UNIVERSITE LIBRE DE BRUXELLES

Belgium

Net EU contribution

€ 256 320,00

Address

Avenue Franklin Roosevelt 50
1050 Bruxelles

Region

Région de Bruxelles-Capitale/Brussels Hoofdstedelijk Gewest › Région de Bruxelles-Capitale/ Brussels Hoofdstedelijk Gewest › Arr. de Bruxelles-Capitale/Arr. Brussel-Hoofdstad

Activity type

Higher or Secondary Education Establishments

Links

Other funding

€ 0,00