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Imaging the proteome at the nanoscale

Project description

High-throughput imaging of proteins using nanobodies

The conventional detection of proteins by imaging employs fluorophores or antibodies directed at individual proteins. However, this methodology cannot be upscaled and employed in a high-throughput omics approach. The EU-funded IMAGEOMICS project aims to address this limitation through affinity probes that bind to specific peptide sequences located in more than one protein. Scientists will develop nanobodies that bind to such peptides and use them to label biological samples. The IMAGEOMICS strategy will provide information on the whole proteome of cells and tissues, paving the way for improved diagnostics for various diseases.

Call for proposal

H2020-FETOPEN-2018-2019-2020-01
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Coordinator

UNIVERSITAETSMEDIZIN GOETTINGEN - GEORG-AUGUST-UNIVERSITAET GOETTINGEN - STIFTUNG OEFFENTLICHEN RECHTS
Address
Robert-koch-strasse 40
37075 Goettingen
Germany

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Activity type
Higher or Secondary Education Establishments
EU contribution
€ 857 190

Participants (3)

BAR ILAN UNIVERSITY
Israel
EU contribution
€ 1 012 500
Address
Bar Ilan University Campus
52900 Ramat Gan

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Activity type
Higher or Secondary Education Establishments
NANOTAG BIOTECHNOLOGIES GMBH
Germany
EU contribution
€ 1 056 666,25
Address
Rudolf Wissell Strasse 28a
37079 Gottingen

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Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
KUNGLIGA TEKNISKA HOEGSKOLAN
Sweden
EU contribution
€ 769 625
Address
Brinellvagen 8
100 44 Stockholm

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Activity type
Higher or Secondary Education Establishments