Bioprinting on-chip microphysiological models of humanized kidney tubulointerstitium

Informazioni relative al progetto

BIRDIE

ID dell’accordo di sovvenzione: 964452

DOI

10.3030/964452

Progetto chiuso

Data della firma CE 21 Dicembre 2020

Data di avvio 1 Marzo 2021

Data di completamento 31 Marzo 2025

Finanziato da

• EXCELLENT SCIENCE - Future and Emerging Technologies (FET)

Costo totale

€ 2 999 425,00

Contributo UE

€ 2 999 425,00

Coordinato da

UNIVERSITEIT MAASTRICHT
Netherlands

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Demonstrators, pilots, prototypes (3)

Prototype of the new chip

Demonstrator of the new chip design as described in T4.2 (Prototyping and qualification of the newly designed chip)

Integration of imaging module for QC

Demonstrator developed in T3.2 (Bioprinting QC integration) where monitoring of bioprinted constructs will be integrated by FC.

Biopixlar with integrated Biopen

Demonstrator developed in T3.1 (T3.1 Hybrid bioprinting platform) combining the two technologies of FC.

Websites, patent fillings, videos etc. (1)

Website BIRDIE project

Website and Logo of the BIRDIE project

Documents, reports (3)

Stakeholder Workshops 2

Newsletter with workshop meeting outputs

Stakeholder Workshops 3

Newsletter with workshop meeting outputs.

Stakeholder Workshops 1

Newsletter with workshop meeting outputs

Pubblicazioni

Other (2)

Dimethyl sulfoxide primes induced pluripotent stem cells for more efficient nephron progenitor and kidney organoid differentiation

Autori: Helen Kearney, Aleksandra Rak-Raszewska, Adrián Seijas-Gamardo, Enrique Escarda-Castro, Paul Wieringa, Lorenzo Moroni, Carlos Mota
Pubblicato in: 2025
Editore: Cold Spring Harbor Laboratory
DOI: 10.1101/2025.02.07.637033

A Sacrificial 3D Printed Vessel-on-Chip Demonstrates a Versatile Approach to Model Connective Tissue Pathology

Autori: Jonas Jäger, Phil Berger, Andrew I. Morrison, Hendrik Erfurth, Maria Thon, Eva-Maria Dehne, Susan Gibbs, Jasper J. Koning
Pubblicato in: 2025
Editore: Cold Spring Harbor Laboratory
DOI: 10.1101/2025.02.06.636821

Peer reviewed articles (4)

Bioprinting of Alginate-Norbornene bioinks to create a versatile platform for kidney in vitro modeling

Autori: Francesca Perin, Anna Ricci, Sveva Fagiolino, Aleksandra Rak-Raszewska, Helen Kearney, Jopeth Ramis, Ivo Bereen, Matthew Baker, Devid Maniglio, Antonella Motta, Lorenzo Moroni, Carlos Mota
Pubblicato in: Bioactive Materials, Numero 49, 2025, Pagina/e 550-563, ISSN 2452-199X
Editore: KeAi
DOI: 10.1016/j.bioactmat.2025.03.010

Modeling a Dynamic Printability Window on Polysaccharide Blend Inks for Extrusion Bioprinting

Autori: Francesca Perin; Eugenia Spessot; Anna Famà; Alessio Bucciarelli; Emanuela Callone; Carlos Mota; Antonella Motta; Devid Maniglio
Pubblicato in: ACS Biomaterial Science and Engineering, Numero 3, 2023, ISSN 2373-9878
Editore: American Chemical Society
DOI: 10.1021/acsbiomaterials.2c01143

A perfused iPSC-derived proximal tubule model for predicting drug-induced kidney injury

Autori: Michelle Lechtenberg, Coraline Chéneau, Kevin Riquin, Leopold Koenig, Carlos Mota, Franck Halary, Eva-Maria Dehne
Pubblicato in: Toxicology in Vitro, Numero 105, 2025, Pagina/e 106038, ISSN 0887-2333
Editore: Elsevier BV
DOI: 10.1016/j.tiv.2025.106038

Bioprinting of kidney in vitro models: cells, biomaterials, and manufacturing techniques

Autori: Maaike F.J. Fransen, Gabriele Addario, Carlijn V.C. Bouten, Franck Halary, Lorenzo Moroni, Carlos Mota
Pubblicato in: Essays in Biochemistry, 2021, ISSN 0071-1365
Editore: Portland Press, Ltd.
DOI: 10.1042/ebc20200158