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Machine Learning Artificial Intelligence Early Detection Stroke Atrial Fibrillation

Objective

Atrial fibrillation (AF) and stroke are major health care problems in Europe. They are most often the clinical expression of atrial cardiomyopathy, which is under-recognised due to the lack of specific diagnostic tools. Multidisciplinary research and stratified approaches are urgently needed to prevent, diagnose, and treat AF and stroke and preempt the AF-related threat to healthy ageing in Europe. MAESTRIA is a European consortium of 18 clinicians, scientists and Pharma industrials who are at the forefront of research and medical care of AF and stroke patients. It will create multi-parametric digital tools based on a new generation of biomarkers that integrate artificial intelligence (AI) processing and big data from cutting edge imaging, electrocardiography and omics technologies. It will develop novel biomarkers, diagnostic tools and personalized therapies for atrial cardiomyopathy. Digital Twin technologies, a rich data integrator combining biophysics and AI will be used to generate virtual twins of the human atria using patient-specific data. Unique experimental large-animal models, ongoing patient cohorts and a prospective MAESTRIA cohort of patients will provide rigorous validation for new biomarkers and newly developed tools. A dedicated core lab will collect and homogenize clinical data. MAESTRIA will be organized as a user-centered platform, easily accessible via clinical parameters routinely used in European hospitals. A Scientific Advisory Board comprising potential clinician users will help MAESTRIA meet clinical and market needs. Dissemination and visibility of the MAESTRIA consortium mission will benefit from participation of the German Competence Network on Atrial Fibrillation (AFNET), and support from the European Society of Cardiology, clinicians, scientists, and other professional societies. MAESTRIA will be ready to tackle the major challenges of data integration and personalized medicine focused on atrial cardiomyopathy, AF and stroke.

Field of science

  • /medical and health sciences/basic medicine/neurology/stroke
  • /natural sciences/computer and information sciences/artificial intelligence
  • /natural sciences/computer and information sciences/data science/big data

Call for proposal

H2020-SC1-2020-Single-Stage-RTD
See other projects for this call

Funding Scheme

RIA - Research and Innovation action

Coordinator

SORBONNE UNIVERSITE
Address
21 Rue De L'ecole De Medecine
75006 Paris
France
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 2 848 500

Participants (17)

ASSISTANCE PUBLIQUE HOPITAUX DE PARIS
France
EU contribution
€ 660 758,75
Address
3 Avenue Victoria
75000 Paris
Activity type
Research Organisations
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
United Kingdom
EU contribution
€ 811 862,50
Address
Wellington Square University Offices
OX1 2JD Oxford
Activity type
Higher or Secondary Education Establishments
THE UNIVERSITY OF BIRMINGHAM
United Kingdom
EU contribution
€ 435 191,25
Address
Edgbaston
B15 2TT Birmingham
Activity type
Higher or Secondary Education Establishments
KOMPETENZNETZ VORHOFFLIMMERN E.V.
Germany
EU contribution
€ 2 476 810
Address
Mendelstrasse 11
48149 Muenster
Activity type
Other
UNIVERSITAETSKLINIKUM ESSEN
Germany
EU contribution
€ 370 000
Address
Hufelandstrasse 55
45147 Essen
Activity type
Higher or Secondary Education Establishments
UNIVERSITEIT MAASTRICHT
Netherlands
EU contribution
€ 1 249 837,50
Address
Minderbroedersberg 4-6
6200 MD Maastricht
Activity type
Higher or Secondary Education Establishments
ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON
Greece
EU contribution
€ 574 000
Address
6 Christou Lada Str
10561 Athina
Activity type
Higher or Secondary Education Establishments
CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III (F.S.P.)
Spain
EU contribution
€ 801 000
Address
Calle Melchor Fernandez Almagro 3
28029 Madrid
Activity type
Research Organisations
THE GENERAL HOSPITAL CORPORATION
United States
EU contribution
€ 500 000
Address
Fruit Street 55
02114 Boston Ma
Activity type
Other
IMT TRANSFERT
France
EU contribution
€ 581 250
Address
2-2 Bis Villa Thoreton
75015 Paris
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
CENTRE INTEGRE UNIVERSITAIRE DE SANTE ET DE SERVICES SOCIAUX DE L ESTRIE-CENTRE HOSPITALIER UNIVERSITAIRE DE SHERBROOKE
Canada
EU contribution
€ 0
Address
375 Rue Argyll
J1J 3H5 Sherbrooke
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
SIEMENS HEALTHCARE GMBH
Germany
EU contribution
€ 726 156,25
Address
Henkestrasse 127
91052 Erlangen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
CARISTO DIAGNOSTICS LIMITED
United Kingdom
EU contribution
€ 531 250
Address
234 Botley Road New Barclays House
OX2 0HP Oxford
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
OWKIN FRANCE
France
EU contribution
€ 471 875
Address
12 Rue Martel
75010 Paris
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
IDOVEN 1903 SL
Spain
EU contribution
€ 487 745
Address
C/principe De Vergara 128 Esc Dr Piso En
28002 Madrid
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
PREVENTICUS GMBH
Germany
EU contribution
€ 205 000
Address
Ernst-abbe-strasse 15
07743 Jena
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
YOURRHYTHMICS
Netherlands
EU contribution
€ 184 075
Address
Oxfordlaan 55
6229 EV Maastricht
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)