Individualized CARE for Older Persons with Complex Chronic Conditions at home and in nursing homes

Projektinformationen

I-CARE4OLD

ID Finanzhilfevereinbarung: 965341

DOI

10.3030/965341

Projekt abgeschlossen

EK-Unterschriftsdatum 4 Februar 2021

Startdatum 1 Juni 2021

Enddatum 31 Mai 2025

Finanziert unter

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Gesamtkosten

€ 6 492 416,59

EU-Beitrag

€ 5 832 536,25

Koordiniert durch

STICHTING AMSTERDAM UMC
Netherlands

CORDIS bietet Links zu öffentlichen Ergebnissen und Veröffentlichungen von HORIZONT-Projekten.

Links zu Ergebnissen und Veröffentlichungen von RP7-Projekten sowie Links zu einigen Typen spezifischer Ergebnisse wie Datensätzen und Software werden dynamisch von OpenAIRE abgerufen.

Leistungen

Documents, reports (16)

Guidance for professionals to interpret the algorithms on pharmacological treatment

Guidance for professionals to interpret the algorithms on prognosis of health outcomes

Pilot report POL

Description of the ICARE4OLD pilot study design and pilot learnings for the introduction and integration of the interRAI assessments into POL. Customisations and translations will be described of the test-case pilot in POL.

Details on the data which will be imported to/exported from the EU

In WP7 only descriptions and codes of algorithms and data on user experiences will be shared. Therefor, no personal or sensitive data need to be transferred from the EU to a non-EU country or international organisation. So GDPR will not be violated.

Publication of results in public registry
List of non-pharmacological interventions in the available data repositories

List nonpharmacological interventions in the available data repositories

Pilot protocol including informed consent procedures

The protocol comprises ethical approval procedures1. Description of study design3. The procedures and criteria that will be used to identify/recruit research participants.2. Informed consent procedures that will be implemented for the participation of humans.4. Templates of the informed consent forms and information sheets (in English)

Characterization HC and NH patients' groups

Homogeneous groups of vulnerable older adults in the community and in nursing homes are characterized and have operational definitions.

Longitudinal analysis of the effect of antipsychotic use on behavior disturbance in LTC homes.
Pilot report CZ

Description of the ICARE4OLD pilot study design and pilot learnings for the introduction and integration of the interRAI assessments into CZ. Customisations and translations will be described of the test-case pilot in CZ.

Guidance for professionals to interpret the algorithms on non-pharmacological treatment

Guidance for professionals to interpret the algorithms

Communication & Dissemination plan

A communication dissemination plan

Declaration of compliance with national legal frameworks

Special derogations pertaining to the rights of data subjects or the processing health data have been established under the national legislation of EU the country where the research takes place and submit a declaration of compliance with respective national legal framework(s).

Consensus document on the selected pharmacological treatments

Consensus document on the selected pharmacological treatments that will be investigated on their modifying impact

Ethical approvals

Ethical approvals from pilot sites1. Templates of the informed consent forms and information sheets in language and terms intelligible to the participants2. Copies of opinions/approvals by ethics committees and/or competent authorities for the research with humans.3. Description of measures to protect research participants who might be vulnerable and minimise the risks.4. The beneficiary must confirm whether the Data Protection Officer (DPO) from VUMC is responsible for the personal data processing activities of the whole project. If not, they must provide the contact details of the DPOs from other institutions.

Identification of risk profiles for adverse outcomes during the COVID-19 pandemic
Output that can be understood by care professionals

In this WP risk prediction models on patient outcomes are developped and validated that need to be understood by care professionals.

Open Research Data Pilot (2)

DMP and anonymisation plan PILOT

Data management plan pilot.This includes -a description of the technical and organisational measures that will be implemented to safeguard the rights and freedoms of the data subjects respectively research participants.-descriptions of the security measures that will be implemented to prevent unauthorised access to personal data or the equipment used for processing.-procedures to anonymise study participants.

DMP and anonymisation/pseudonymisation Plan for real-life data

Initial Data Management Plan (DMP), adaptions will be made during the project's life span; these will be incorporated in the updated versions of the DMP.It also holds and anonymisation/pseudonymisation plan for linking and using real-life data.

Websites, patent fillings, videos etc. (1)

ICARE4OLD Closing conference

ICARE4OLD Closing conference report

Veröffentlichungen

Peer reviewed articles (28)

Changes in Urinary Continence After Admission to a Complex Care Setting: A Multistate Transition Model

Autoren: Melissa Northwood, Luke A. Turcotte, Caitlin McArthur, Bonaventure A. Egbujie, Katherine Berg, Veronique M. Boscart, George A. Heckman, John P. Hirdes, Adrian S. Wagg
Veröffentlicht in: Journal of the American Medical Directors Association, Ausgabe 23, 2022, Seite(n) 1683-1690.e2, ISSN 1525-8610
Herausgeber: Lippincott Williams & Wilkins Ltd.
DOI: 10.1016/j.jamda.2022.06.019

The prevalence of non-pharmacological interventions in older homecare recipients: an overview from six European countries

Autoren: Eline C. M. Kooijmans, Emiel O. Hoogendijk, Jitka Pokladníková, Louk Smalbil, Katarzyna Szczerbińska, Ilona Barańska, Adrianna Ziuziakowska, Daniela Fialová, Graziano Onder, Anja Declercq, Harriet Finne-Soveri, Mark Hoogendoorn, Hein P. J. van Hout, Karlijn J. Joling
Veröffentlicht in: European Geriatric Medicine, Ausgabe 15, 2024, Seite(n) 243-252, ISSN 1878-7649
Herausgeber: Elsevier Masson
DOI: 10.1007/s41999-023-00868-w

Factors Associated with Mood Transitions among Older Canadian Long-Term Care Residents: A Multistate Transition Model

Autoren: Reem T. Mulla, John P. Hirdes, Carrie McAiney, George Heckman
Veröffentlicht in: Journal of the American Medical Directors Association, Ausgabe 26, 2025, Seite(n) 105612, ISSN 1525-8610
Herausgeber: Lippincott Williams & Wilkins Ltd.
DOI: 10.1016/j.jamda.2025.105612

Systematic review of the performance evaluation of clinicians with or without the aid of machine learning clinical decision support system

Autoren: Mikko Nuutinen, Riikka-Leena Leskelä
Veröffentlicht in: Health and Technology, Ausgabe 13, 2023, Seite(n) 557-570, ISSN 2190-7188
Herausgeber: Springer Verlag
DOI: 10.1007/s12553-023-00763-1

Trajectories of functional decline and predictors in long-term care settings: a retrospective cohort analysis of Canadian nursing home residents

Autoren: Bonaventure Amandi Egbujie, Luke Andrew Turcotte, George Heckman, John P Hirdes
Veröffentlicht in: Age and Ageing, Ausgabe 53, 2025, ISSN 0002-0729
Herausgeber: Oxford University Press
DOI: 10.1093/ageing/afae264

Prevalence of potentially inappropriate prescribing in older adults in Central and Eastern Europe: a systematic review and synthesis without meta-analysis

Autoren: Jovana Brkic, Daniela Fialova, Betul Okuyan, Ingrid Kummer, Sofija Sesto, Andreas Capiau, Maja Ortner Hadziabdic, Konstantin Tachkov, Veera Bobrova
Veröffentlicht in: Scientific Reports, Ausgabe 12, 2022, ISSN 2045-2322
Herausgeber: Nature Publishing Group
DOI: 10.1038/s41598-022-19860-8

Antipsychotic Medication Use Among Newly Admitted Long-term Care Residents During the COVID-19 Pandemic in Canada

Autoren: Luke A Turcotte, George A Heckman, Caitlin McArthur, Margaret Saari, Chi-Ling Joanna Sinn, Krista Mathias, Asif Khowaja, Nathan M Stall, John P Hirdes
Veröffentlicht in: Health Services Insights, Ausgabe 17, 2025, ISSN 1178-6329
Herausgeber: SAGE Publications
DOI: 10.1177/11786329241300827

Prevalence and Determinants of Multimorbidity, Polypharmacy, and Potentially Inappropriate Medication Use in the Older Outpatients: Findings from EuroAgeism H2020 ESR7 Project in Ethiopia

Autoren: Akshaya Srikanth Bhagavathula, Mohammed Assen Seid, Aynishet Adane, Eyob Alemayehu Gebreyohannes, Jovana Brkic, Daniela Fialová
Veröffentlicht in: Pharmaceuticals, Ausgabe 14, 2024, Seite(n) 844, ISSN 1424-8247
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ph14090844

The Medical Complexity of Newly Admitted Long-Term Care Residents Before and During the COVID-19 Pandemic in Ontario, British Columbia, and Alberta: A Serial Cross-Sectional Study

Autoren: Razan Al-Sharkawi, Luke A Turcotte, John P Hirdes, George Heckman, Caitlin McArthur
Veröffentlicht in: Health Services Insights, Ausgabe 17, 2024, ISSN 1178-6329
Herausgeber: Sage publications Inc
DOI: 10.1177/11786329241266675

Mortality prediction models for community-dwelling older adults: A systematic review

Autoren: Collin J.C. Exmann, Eline C.M. Kooijmans, Karlijn J. Joling, George L. Burchell, Emiel O. Hoogendijk, Hein P.J. van Hout
Veröffentlicht in: Ageing Research Reviews, Ausgabe 101, 2024, Seite(n) 102525, ISSN 1568-1637
Herausgeber: Elsevier BV
DOI: 10.1016/j.arr.2024.102525

Author Correction: Deprescribing potential of commonly used medications among community-dwelling older adults: insights from a pharmacist’s geriatric assessment

Autoren: Iva Bužančić, Margita Držaić, Ingrid Kummer, Maja Ortner Hadžiabdić, Jovana Brkić, Daniela Fialová
Veröffentlicht in: Scientific Reports, Ausgabe 14, 2024, ISSN 2045-2322
Herausgeber: Nature Publishing Group
DOI: 10.1038/s41598-024-60073-y

Prevalence, country-specific prescribing patterns and determinants of benzodiazepine use in community-residing older adults in 7 European countries

Autoren: Anna Lukačišinová, Jindra Reissigová, Maja Ortner-Hadžiabdić, Jovana Brkic, Betul Okuyan, Daisy Volmer, Ivana Tadić, Pilar Modamio, Eduardo L. Mariño, Konstantine Tachkov, Rosa Liperotti, Graziano Onder, Harriet Finne-Soveri, Hein van Hout, Elizabeth P. Howard, Daniela Fialová
Veröffentlicht in: BMC Geriatrics, Ausgabe 24, 2024, ISSN 1471-2318
Herausgeber: BioMed Central
DOI: 10.1186/s12877-024-04742-7

Optimising the care for older persons with complex chronic conditions in home care and nursing homes: design and protocol of I-CARE4OLD, an observational study using real-world data

Autoren: Emiel O Hoogendijk, Graziano Onder, Louk Smalbil, Davide L Vetrano, John P Hirdes, Elizabeth P Howard, John N Morris, Daniela Fialová, Katarzyna Szczerbińska, Eline CM Kooijmans, Mark Hoogendoorn, Anja Declercq, Johanna De Almeida Mello, Riikka-Leena Leskelä, Jokke Häsä, Johanna Edgren, Georg Ruppe, Rosa Liperoti, Karlijn J Joling, Hein PJ van Hout
Veröffentlicht in: BMJ Open, Ausgabe 13, 2023, Seite(n) e072399, ISSN 2044-6055
Herausgeber: BMJ Publishing Group
DOI: 10.1136/bmjopen-2023-072399

Polypharmacy and potentially inappropriate prescribing of benzodiazepines in older nursing home residents

Autoren: Ingrid Kummer, Jindra Reissigová, Anna Lukačišinová, Maja Ortner Hadžiabdić, Matej Stuhec, Rosa Liperoti, Harriet Finne-Soveri, Graziano Onder, Hein van Hout, Daniela Fialová
Veröffentlicht in: Annals of Medicine, Ausgabe 56, 2024, ISSN 0785-3890
Herausgeber: Taylor & Francis
DOI: 10.1080/07853890.2024.2357232

Identifying Potential Drug-Related Problems Among Geriatric Patients With Use of an Integrated Clinical Decision Support Tool

Autoren: Veera Bobrova, Daniela Fialová, Shane Desselle, Jyrki Heinämäki and Daisy Volmer
Veröffentlicht in: Frontiers in Pharmacology, Ausgabe 13, 2022, Seite(n) 761787, ISSN 1663-9812
Herausgeber: Frontiers Media S.A.
DOI: 10.3389/fphar.2022.761787

Protocol of the pilot study to test and evaluate the iCARE tool: a machine learning-based e-platform tool to make health prognoses and support decision-making for the care of older persons with complex chronic conditions

Autoren: Anna-Maria Hiltunen, Ira Haavisto, Mikko Nuutinen, Mari Lahelma, Anna Salminen, Johanna de Almeida Mello, Rosa Liperoti, Elizabeth P Howard, Daniela Fialová, Katarzyna Szczerbińska, Mor Alon, Ilona Barańska, Collin Exmann, Anja Declercq, Wiebe Boorsma, Graziano Onder, Hein P J van Hout, Riikka-Leena Leskelä
Veröffentlicht in: BMJ Open, Ausgabe 15, 2025, Seite(n) e101234, ISSN 2044-6055
Herausgeber: BMJ Publishing Group
DOI: 10.1136/bmjopen-2025-101234

Functional Decline in Long-Term Care Homes in the First Wave of the COVID-19 Pandemic: A Population-based Longitudinal Study in Five Canadian Provinces

Autoren: Bonaventure A. Egbujie, Luke A. Turcotte, George A. Heckman, John N. Morris, John P. Hirdes
Veröffentlicht in: Journal of the American Medical Directors Association, Ausgabe 25, 2024, Seite(n) 282-289, ISSN 1525-8610
Herausgeber: Lippincott Williams & Wilkins Ltd.
DOI: 10.1016/j.jamda.2023.09.007

The prevalence and prescribing patterns of benzodiazepines and Z-drugs in older nursing home residents in different European countries and Israel: retrospective results from the EU SHELTER study

Autoren: Anna Lukačišinová, Daniela Fialová, Nancye May Peel, Ruth Eleanor Hubbard, Jovana Brkic, Graziano Onder, Eva Topinková, Jacob Gindin, Tamar Shochat, Leonard Gray, Roberto Bernabei
Veröffentlicht in: BMC Geriatrics, Ausgabe 21, 2021, ISSN 1471-2318
Herausgeber: BioMed Central
DOI: 10.1186/s12877-021-02213-x

Cognitive Change Among Nursing Home Residents: CogRisk-NH Scale Development to Predict Decline

Autoren: John N. Morris, Elizabeth P. Howard, Erez Schachter, Sharran Burney, Anna Laytham, Daniela Fialova, Emiel O. Hoogendijk, Rosa Liperoti, Hein P.J. van Hout, Davide Liborio Vetrano
Veröffentlicht in: Journal of the American Medical Directors Association, Ausgabe 24, 2023, Seite(n) 1405-1411, ISSN 1525-8610
Herausgeber: Lippincott Williams & Wilkins Ltd.
DOI: 10.1016/j.jamda.2023.06.011

Defining and Categorizing Nonpharmacologic Interventions in the Older Population: A Systematic Review

Autoren: Eline C.M. Kooijmans, Emiel O. Hoogendijk, Natalia Drapała, Olena Antonenko, George L. Burchell, Ilona Barańska, Jitka Pokladníková, Katarzyna Szczerbińska, Daniela Fialová, Hein P.J. van Hout, Karlijn J. Joling
Veröffentlicht in: Journal of the American Medical Directors Association, Ausgabe 26, 2024, Seite(n) 105306, ISSN 1525-8610
Herausgeber: Lippincott Williams & Wilkins Ltd.
DOI: 10.1016/j.jamda.2024.105306

Incidence of New Mood Symptoms Among Residents in Canadian Long-Term Care Homes During the COVID-19 Pandemic: A Longitudinal Analysis

Autoren: Reem T. Mulla, John P. Hirdes, Luke Andrew Turcotte, Colleen Webber, Micaela Jantzi, Carrie McAiney, George Heckman
Veröffentlicht in: The American Journal of Geriatric Psychiatry: Open Science, Education, and Practice, Ausgabe 5, 2025, Seite(n) 109-121, ISSN 2950-3868
Herausgeber: Elsevier BV
DOI: 10.1016/j.osep.2025.01.002

Patterns of Transient and Terminal Transitions in Activities of Daily Living Performance Levels among Long-Term Care Residents: A Multistate Markov’s Model Analysis of Population-Based Longitudinal Data in Canada

Autoren: Bonaventure A. Egbujie, Luke A. Turcotte, Reem T. Mulla, George A. Heckman, John P. Hirdes
Veröffentlicht in: Journal of the American Medical Directors Association, Ausgabe 26, 2025, Seite(n) 105565, ISSN 1525-8610
Herausgeber: Lippincott Williams & Wilkins Ltd.
DOI: 10.1016/j.jamda.2025.105565

Risk of Death Among Nursing Home Residents: A Cross-National Perspective

Autoren: John N. Morris, Elizabeth P. Howard, Erez Schachter, Vanja Pešić, Anna K. Laytham, Sharran N. Burney
Veröffentlicht in: Journal of the American Medical Directors Association, Ausgabe 25, 2024, Seite(n) 105142, ISSN 1525-8610
Herausgeber: Lippincott Williams & Wilkins Ltd.
DOI: 10.1016/j.jamda.2024.105142

Acknowledging the Complexity of Antipsychotic Use in Long-Term Care During the COVID-19 Pandemic

Autoren: Luke Andrew Turcotte, Caitlin McArthur, Jeff W Poss, George Heckman, Lori Mitchell, John Morris, Andrea D Foebel, John P Hirdes
Veröffentlicht in: Health Services Insights, Ausgabe 16, 2025, ISSN 1178-6329
Herausgeber: SAGE Publications
DOI: 10.1177/11786329231195211

Deprescribing potential of commonly used medications among community-dwelling older adults: insights from a pharmacist’s geriatric assessment

Autoren: Iva Bužančić, Margita Držaić, Ingrid Kummer, Maja Ortner Hadžiabdić, Jovana Brkić, Daniela Fialová
Veröffentlicht in: Scientific Reports, Ausgabe 14, 2024, ISSN 2045-2322
Herausgeber: Nature Publishing Group
DOI: 10.1038/s41598-024-56780-1

Long-Term Care Resident Health and Quality of Care During the COVID-19 Pandemic: A Synthesis Analysis of Canadian Institute for Health Information Data Tables.

Autoren: Luke Andrew Turcotte, Caitlin McArthur, Jeff W Poss, George Heckman, Lori Mitchell, John Morris, Andrea D Foebel, and John P Hirdes
Veröffentlicht in: Health Services Insights., Ausgabe 16, 2023, ISSN 2158-2440
Herausgeber: SAGE Publications Inc.
DOI: 10.1177/11786329231174745

A Longitudinal Treatment Effect Analysis of Antipsychotics on Behavior of Residents in Long-Term Care

Autoren: Daniel E.C. Leme, Krista Mathias, Amanda Mofina, Rosa Liperoti, Gustavo S. Betini, John P. Hirdes
Veröffentlicht in: Journal of the American Medical Directors Association, Ausgabe 25, 2024, Seite(n) 105255, ISSN 1525-8610
Herausgeber: Lippincott Williams & Wilkins Ltd.
DOI: 10.1016/j.jamda.2024.105255

Predicting unplanned admissions to hospital in older adults using routinely recorded general practice data: development and validation of a prediction model

Autoren: Jet H Klunder, Martijn W Heymans, Iris van der Heide, Robert A Verheij, Otto R Maarsingh, Hein PJ van Hout, Karlijn J Joling
Veröffentlicht in: British Journal of General Practice, Ausgabe 74, 2024, Seite(n) e628-e636, ISSN 0960-1643
Herausgeber: Royal College of General Practitioners
DOI: 10.3399/bjgp.2023.0350

Non-peer reviewed articles (2)

Predictors of improvement in urinary incontinence in the postacute setting: A Canadian cohort study

Autoren: Egbujie BA; Northwood M; Turcotte LA; McArthur C; Berg K; Heckman GA; Wagg AS; Hirdes JP
Veröffentlicht in: Neurology and Urodynamics, Ausgabe Volume41, Ausgabe8, 2022, Seite(n) 1749-1763, ISSN 1520-6777
Herausgeber: Wile Online Library
DOI: 10.1002/nau.25018

Examining the effect of the first wave of the COVID-19 pandemic on home care recipients’ instrumental activities of daily living capacity

Autoren: McArthur C; Faller-Saunders A; Turcotte LA; Sinn CJ; Berg K; Morris JN; Hirdes JP
Veröffentlicht in: Journal of the American Medical Directors Association, Ausgabe VOLUME 23, ISSUE 9,, 2022, Seite(n) P1609.E1-, ISSN 1525-8610
Herausgeber: Lippincott Williams & Wilkins Ltd.
DOI: 10.1016/j.jamda.2022.06.015