CORDIS provides links to public deliverables and publications of HORIZON projects.
Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .
Exploitable results
The project lead to a number of findings that may give important insights into the mechanism of cell death. In particular, monoclonal antibodies to the novel LAK cells proteins were obtained. These antibodies are used to screen cDNA expression libraries prepared from LAK cells RNA. The antibodies obtained possessed the immunocrossreactivity to the LAK cells proteins and the novel cytotoxic proteins TAG7. The affinity-sorbent with high specificity to LAK cells proteins was prepared. The human TAG7 was found in activated lymphocytes. It was found that both TNF and LAK cells proteins induced apoptotic death in non-metastatic tumour cell lines and did not effect the metastatic tumour cell lines.
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