Obiettivo The basic principles underlying tumour immunology have evolved considerably. It has been established that :(1) the normal immune system is rarely a significant barrier to tumour growth, (2) most tumours are antigenic but few spontaneous tumours are immunogenic and (3) manipulation of the immune system can result in complete tumour eradication. Although the first two principles are well established, the third has been shown in only a few cases so far. In fact, immunotherapy often fails or is otherwise inadequate even in the presence of a potent immune response. It is therefore crucial to probe (1) which properties of the immune system contribute to poor immunogenicity and how the this property can be stimulated and (2) how cancer cells present tumour-related barriers to immunotherapy. Campo scientifico medical and health sciencesclinical medicineoncologymedical and health sciencesbasic medicineimmunologyimmunotherapy Programma(i) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Argomento(i) 1.1.1.-7. - Chronic and degenerative diseases, cancer, diabetes, cardivascular diseases and rare diseases Invito a presentare proposte Data not available Meccanismo di finanziamento ACM - Preparatory, accompanying and support measures Coordinatore SAINT SAVAS CANCER HOSPITAL Contributo UE Nessun dato Indirizzo Alexandras Ave 171 11522 ATHENS Grecia Mostra sulla mappa Costo totale Nessun dato