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Development of environmental modules for evaluation of toxicity of pesticide residues in agriculture

Obiettivo

DEMETRA' s objective is to produce software for toxicity prediction of pesticides and related compounds, for evaluation within the Dossier for pesticide registration. We will involve end-users from government and industry and ecotoxicologists to get a sound basis. Suitable data sets will be defined, with pesticides and their toxicity values in 5 organisms. We will calculate chemical descriptors of pesticides. We will develop many models using advanced computational tools, like multivariate analysis, neural networks, fuzzy logic, machine learning, genetic algorithms, etc. We will combine the most successful models within a hybrid system. This process will be done in parallel for the 5 endpoints. The so obtained 5 hybrid systems will be put on the web for free access. Further dissemination will be obtained within a workshop.

Meccanismo di finanziamento

CSC - Cost-sharing contracts

Coordinatore

MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH
Indirizzo
62,Via Eritrea 62
20157 Milano
Italia

Partecipanti (5)

BIOCHEMICS CONSULTING SAS
Francia
Indirizzo
Innovation Center - Rue Leonoard De Vinci, 16
45074 Orleans
DEPARTMENT FOR ENVIRONMENT, FOOD AND RURAL AFFAIRS
United Kingdom
Indirizzo
Nobel House, Smith Square 17
SW1P 36JR London
POLYTECHNIC OF MILAN
Italia
Indirizzo
Piazza Leonardo Da Vinci 32
20133 Milano
SYNGENTA CROP PROTECTION AG
Svizzera
Indirizzo

4002 Basel
UNIVERSITY 'DUNAREA DE JOS' OF GALATI
Romania
Indirizzo
Domneasca 111
6200 Galati