Objective
Ochratoxin A (OA), a mycotoxin, is a suspect kidney carcinogen and has been shown to have teratogenic activity. Its occurrence as a consequence of fungal attack in foods from plant origin such as cereals and beans is well known and widely reported in the scientific literature. The presence of OA in edible animal tissues and particularly in pig kidneys, as a result of consumption of contaminated feed has been demonstrated in Denmark and Sweden. Recently, individual member states have begun to set up tolerance limits. A guideline for cereals exists in France and in the United Kingdom and industrial limit for cereals is used. The project was set up to improve the reliability of the methods to determine OA and to provide blank and naturally contaminated wheat and lyophilised pig kidney reference materials (RM).
A pair of wheat reference materials have been prepared. They consist of naturally contaminated samples containing the toxin at levels close to the recommended (voluntary) action limits, and samples having low levels to provide a means of checking analytical background and recovery efficiency. An intercomparison study with about 30 European laboratories was carried out and the results showed that the major difficulties arise from the clean up step of the method used.
Ochratoxin A (OA), a mycotoxin, is a suspect kidney carcinogen and has been shown to have teratogenic activity.
Its occurrence as a consequence of fungal attack in foods from plant origin such as cereals and beans is well known and widely reported in the scientific literature. The presence of OA in edible animal tissues and particularly in pig kidneys, as a result of consumption of contaminated feed has been demonstrated in Denmark and Sweden.
Recently, individual Member States have begun to set up tolerance limits. A guideline for cereals exists in France and in the UK an industrial limit for cereals is used.
The objective of the project is to improve the reliability of the methods to determine OA and to provide "blank" and naturally contaminated wheat and lyophilised pig kidney RMs.
Fields of science
Topic(s)
Data not availableCall for proposal
Data not availableFunding Scheme
CSC - Cost-sharing contractsCoordinator
1870 COPENHAGEN V
Denmark
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Participants (28)
8011 GRUB
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YO1 5DE York
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28042 MADRID
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4000 ROSKILDE
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00161 Roma
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70126 Bari
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35000 Rennes
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1900 Lisboa
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TW11 0LY Teddington
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70184 Stuttgart
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NR4 7UQ Norwich
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14195 Berlin
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28220 MAJADAHONDA (MADRID)
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2860 SÖBORG
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75007 UPPSALA
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00101 HELSINKI
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6700 AE WAGENINGEN
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HP12 3QR High Wycombe
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G4 1YT Glasgow
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3720 BA BILTHOVEN
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10044 Stockholm
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15 DUBLIN
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75126 UPPSALA
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3700 AJ ZEIST
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MK44 1LQ Sharnbrook
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28040 MADRID
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3508 TD UTRECHT
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80539 München
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