Obiettivo
Ochratoxin A (OA), a mycotoxin, is a suspect kidney carcinogen and has been shown to have teratogenic activity. Its occurrence as a consequence of fungal attack in foods from plant origin such as cereals and beans is well known and widely reported in the scientific literature. The presence of OA in edible animal tissues and particularly in pig kidneys, as a result of consumption of contaminated feed has been demonstrated in Denmark and Sweden. Recently, individual member states have begun to set up tolerance limits. A guideline for cereals exists in France and in the United Kingdom and industrial limit for cereals is used. The project was set up to improve the reliability of the methods to determine OA and to provide blank and naturally contaminated wheat and lyophilised pig kidney reference materials (RM).
A pair of wheat reference materials have been prepared. They consist of naturally contaminated samples containing the toxin at levels close to the recommended (voluntary) action limits, and samples having low levels to provide a means of checking analytical background and recovery efficiency. An intercomparison study with about 30 European laboratories was carried out and the results showed that the major difficulties arise from the clean up step of the method used.
Ochratoxin A (OA), a mycotoxin, is a suspect kidney carcinogen and has been shown to have teratogenic activity.
Its occurrence as a consequence of fungal attack in foods from plant origin such as cereals and beans is well known and widely reported in the scientific literature. The presence of OA in edible animal tissues and particularly in pig kidneys, as a result of consumption of contaminated feed has been demonstrated in Denmark and Sweden.
Recently, individual Member States have begun to set up tolerance limits. A guideline for cereals exists in France and in the UK an industrial limit for cereals is used.
The objective of the project is to improve the reliability of the methods to determine OA and to provide "blank" and naturally contaminated wheat and lyophilised pig kidney RMs.
Campo scientifico
Argomento(i)
Data not availableInvito a presentare proposte
Data not availableMeccanismo di finanziamento
CSC - Cost-sharing contractsCoordinatore
1870 COPENHAGEN V
Danimarca
Mostra sulla mappa
Partecipanti (28)
8011 GRUB
Mostra sulla mappa
YO1 5DE York
Mostra sulla mappa
28042 MADRID
Mostra sulla mappa
4000 ROSKILDE
Mostra sulla mappa
00161 Roma
Mostra sulla mappa
70126 Bari
Mostra sulla mappa
35000 Rennes
Mostra sulla mappa
1900 Lisboa
Mostra sulla mappa
TW11 0LY Teddington
Mostra sulla mappa
70184 Stuttgart
Mostra sulla mappa
NR4 7UQ Norwich
Mostra sulla mappa
14195 Berlin
Mostra sulla mappa
28220 MAJADAHONDA (MADRID)
Mostra sulla mappa
2860 SÖBORG
Mostra sulla mappa
75007 UPPSALA
Mostra sulla mappa
00101 HELSINKI
Mostra sulla mappa
6700 AE WAGENINGEN
Mostra sulla mappa
HP12 3QR High Wycombe
Mostra sulla mappa
G4 1YT Glasgow
Mostra sulla mappa
3720 BA BILTHOVEN
Mostra sulla mappa
10044 Stockholm
Mostra sulla mappa
15 DUBLIN
Mostra sulla mappa
75126 UPPSALA
Mostra sulla mappa
3700 AJ ZEIST
Mostra sulla mappa
MK44 1LQ Sharnbrook
Mostra sulla mappa
28040 MADRID
Mostra sulla mappa
3508 TD UTRECHT
Mostra sulla mappa
80539 München
Mostra sulla mappa