Objectif
Ochratoxin A (OA), a mycotoxin, is a suspect kidney carcinogen and has been shown to have teratogenic activity. Its occurrence as a consequence of fungal attack in foods from plant origin such as cereals and beans is well known and widely reported in the scientific literature. The presence of OA in edible animal tissues and particularly in pig kidneys, as a result of consumption of contaminated feed has been demonstrated in Denmark and Sweden. Recently, individual member states have begun to set up tolerance limits. A guideline for cereals exists in France and in the United Kingdom and industrial limit for cereals is used. The project was set up to improve the reliability of the methods to determine OA and to provide blank and naturally contaminated wheat and lyophilised pig kidney reference materials (RM).
A pair of wheat reference materials have been prepared. They consist of naturally contaminated samples containing the toxin at levels close to the recommended (voluntary) action limits, and samples having low levels to provide a means of checking analytical background and recovery efficiency. An intercomparison study with about 30 European laboratories was carried out and the results showed that the major difficulties arise from the clean up step of the method used.
Ochratoxin A (OA), a mycotoxin, is a suspect kidney carcinogen and has been shown to have teratogenic activity.
Its occurrence as a consequence of fungal attack in foods from plant origin such as cereals and beans is well known and widely reported in the scientific literature. The presence of OA in edible animal tissues and particularly in pig kidneys, as a result of consumption of contaminated feed has been demonstrated in Denmark and Sweden.
Recently, individual Member States have begun to set up tolerance limits. A guideline for cereals exists in France and in the UK an industrial limit for cereals is used.
The objective of the project is to improve the reliability of the methods to determine OA and to provide "blank" and naturally contaminated wheat and lyophilised pig kidney RMs.
Champ scientifique
Thème(s)
Data not availableAppel à propositions
Data not availableRégime de financement
CSC - Cost-sharing contractsCoordinateur
1870 COPENHAGEN V
Danemark
Voir sur la carte
Participants (28)
8011 GRUB
Voir sur la carte
YO1 5DE York
Voir sur la carte
28042 MADRID
Voir sur la carte
4000 ROSKILDE
Voir sur la carte
00161 Roma
Voir sur la carte
70126 Bari
Voir sur la carte
35000 Rennes
Voir sur la carte
1900 Lisboa
Voir sur la carte
TW11 0LY Teddington
Voir sur la carte
70184 Stuttgart
Voir sur la carte
NR4 7UQ Norwich
Voir sur la carte
14195 Berlin
Voir sur la carte
28220 MAJADAHONDA (MADRID)
Voir sur la carte
2860 SÖBORG
Voir sur la carte
75007 UPPSALA
Voir sur la carte
00101 HELSINKI
Voir sur la carte
6700 AE WAGENINGEN
Voir sur la carte
HP12 3QR High Wycombe
Voir sur la carte
G4 1YT Glasgow
Voir sur la carte
3720 BA BILTHOVEN
Voir sur la carte
10044 Stockholm
Voir sur la carte
15 DUBLIN
Voir sur la carte
75126 UPPSALA
Voir sur la carte
3700 AJ ZEIST
Voir sur la carte
MK44 1LQ Sharnbrook
Voir sur la carte
28040 MADRID
Voir sur la carte
3508 TD UTRECHT
Voir sur la carte
80539 München
Voir sur la carte