Cel The development of novel technologies to diagnose and clinically treat invasive Aspergillus fumigatus infections is the scope of this research consortium. A. fumigatus is a ubiquitous mould whose spores are airborne and thus frequently inhaled. Humans with impaired immunity, e.g. those with haematological malignancies or bone marrow transplant recipients, are at a dramatically increased risk of severe, invasive A. fumigatus infection known as invasive aspergillosis (IA). IA is a rare disease in Europe but causes tremendous costs to the public health sector. Currently definitive diagnosis of IA is only obtained at autopsy or relies on invasive biopsy, an extremely unpleasant procedure which is not always applicable in suffering patients. Thus, a convenient, fast and specific diagnosis of IA is not available forcing clinicians to administer antifungal drugs on spec if a standard antibiotic treatment failed to reduce fever in risk patients. It would be of high financial benefit for clinics and has the potential to increase the survival rates of immuno-compromised patients, if a definitive diagnosis of IA could be obtained early and its response to treatment be monitored. This would allow applying the correct therapy at a dose and duration exactly tailored to patient needs. Equally important is the development of new treatment options which can replace existing systemic antifungal drugs with their known severe side effects. The approach of the consortium is to develop new disease specific tracers based on monoclonal antibodies along with the combined molecular imaging technologies PET/MR and PET/CT. Newly developed tracers shall then be functionalised by a combined labelling with radio-isotopes allowing diagnostic PET imaging but also immuno-radiotherapy, thus representing truly anti-infectious theranostics. This would provide a framework for new tools in the management not only of this rare but life-threatening mycosis but principally also for other infectious hazards. Dziedzina nauki medical and health scienceshealth sciencespublic healthmedical and health sciencesclinical medicineradiologynuclear medicine Program(-y) FP7-HEALTH - Specific Programme "Cooperation": Health Temat(-y) HEALTH.2013.1.2-1 - Development of imaging technologies for therapeutic interventions in rare diseases Zaproszenie do składania wniosków FP7-HEALTH-2013-INNOVATION-1 Zobacz inne projekty w ramach tego zaproszenia System finansowania CP-FP - Small or medium-scale focused research project Koordynator EBERHARD KARLS UNIVERSITAET TUEBINGEN Wkład UE € 2 042 973,65 Adres GESCHWISTER-SCHOLL-PLATZ 72074 Tuebingen Niemcy Zobacz na mapie Region Baden-Württemberg Tübingen Tübingen, Landkreis Rodzaj działalności Higher or Secondary Education Establishments Kontakt administracyjny Bernd Pichler (Prof.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych Uczestnicy (5) Sortuj alfabetycznie Sortuj według wkładu UE Rozwiń wszystko Zwiń wszystko UNIVERSITAETSKLINIKUM ESSEN Niemcy Wkład UE € 1 110 540,34 Adres HUFELANDSTRASSE 55 45147 Essen Zobacz na mapie Region Nordrhein-Westfalen Düsseldorf Essen, Kreisfreie Stadt Rodzaj działalności Higher or Secondary Education Establishments Kontakt administracyjny Matthias Gunzer (Prof.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych ISCA DIAGNOSTICS LIMITED Zjednoczone Królestwo Wkład UE € 894 190,01 Adres TREGOLIS ROAD LOWIN HOUSE TR1 2NA TRURO Zobacz na mapie Rodzaj działalności Private for-profit entities (excluding Higher or Secondary Education Establishments) Kontakt administracyjny Robert Misselbrook (Mr.) Linki Kontakt z organizacją Opens in new window Koszt całkowity Brak danych CHEMATECH SAS Francja Wkład UE € 1 006 110,00 Adres RUE DU BAS DE CHANOT 7 21800 CHEVIGNY SAINT SAUVEUR Zobacz na mapie Rodzaj działalności Private for-profit entities (excluding Higher or Secondary Education Establishments) Kontakt administracyjny Frédéric Boschetti (Dr.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych PAUL SCHERRER INSTITUT Szwajcaria Wkład UE € 531 350,00 Adres FORSCHUNGSTRASSE 111 5232 Villigen Psi Zobacz na mapie Region Schweiz/Suisse/Svizzera Nordwestschweiz Aargau Rodzaj działalności Research Organisations Kontakt administracyjny Irene Walthert (Mrs.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych DANMARKS TEKNISKE UNIVERSITET Dania Wkład UE € 402 377,00 Adres ANKER ENGELUNDS VEJ 101 2800 Kongens Lyngby Zobacz na mapie Region Danmark Hovedstaden Københavns omegn Rodzaj działalności Higher or Secondary Education Establishments Kontakt administracyjny Mikael Jensen (Prof.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych
