Community Research and Development Information Service - CORDIS

MEDICIS-produced radioisotope beams for medicine

From 2015-04-01 to 2019-03-31, ongoing project | MEDICIS-PROMED Website

Project details

Total cost:

EUR 2 829 269,88

EU contribution:

EUR 2 829 269,88

Coordinated in:

Switzerland

Call for proposal:

H2020-MSCA-ITN-2014See other projects for this call

Funding scheme:

MSCA-ITN-ETN - European Training Networks

Objective

Deliverables

  • Design of new containers for theranostic isotope pairs transportation

    New shielded packaging container for nuclear medicine isotopes Objective: To obtain a new technology type B certified shipping container. Expected Results: The typical isotopes (149,152,155,161Tb, 177Lu, 47,48,49Sc, etc) and activities for shipment will first be defined. The European shipping regulations will then be studied in details. First dimensioning of the required shielding, mechanical resistance with be done by Monte-Carlo simulations and by Finite Element Model Mechanical codes. A first prototype will be constructed and checked for effective shielding capacity, leak tightness, shock resistance, etc. A second packaging will be constructed, learning from the prototype, and documentation will be filed to obtain its homologation. Specific innovations, such as direct transfer of the collected isotopes from the separator into the packaging are foreseen.

  • Investigation of imaging probes for ovarian cancer in animal models

    Technical leader: partner organization UNIGE (CH) Investigation of bimodal imaging probes for ovarian cancer in animal models Objective: Develop and validate preclinical imaging techniques for assessment of bio-distribution and performance of new tracers in animal models for prediction of therapeutic efficacy of new radio-labelled compounds at Institute of Translational Molecular Imaging (ITMI) Expected Results: Development of methodology and validation of preclinical techniques. The ESR will be responsible of seeking new methodological techniques and experimental protocols that are suitable for the new compounds that are being evaluated. It will also include the development and validation of biological models that allow quantitative assessment of the efficacy and performance of the tracers as well as their potential efficacy of treatment of the given tumours.

  • Website

    Creation of project website for internal and external use.

Publications

  • The ISOLDE LEGO ® robot: building interest in frontier research
    Author(s): Thomas Elias Cocolios, Kara M Lynch, Emma Nichols
    Published in: Physics Education, issue 52/4, 2017. Page(s) 44004.  ISSN: 0031-9120
    DOI: 10.1088/1361-6552/aa71e4
  • First in-human radiation dosimetry of 68Ga-NODAGA-RGDyK
    Author(s): Silvano Gnesin, Periklis Mitsakis, Francesco Cicone, Emmanuel Deshayes, Vincent Dunet, Augusto F. Gallino, Marek Kosinski, Sébastien Baechler, Franz Buchegger, David Viertl, John O. Prior
    Published in: EJNMMI Research, issue 7/1, 2017. Page(s) 43.  ISSN: 2191-219X
    DOI: 10.1186/s13550-017-0288-x
  • Laser resonance ionization spectroscopy on lutetium for the MEDICIS project
    Author(s): V. Gadelshin, T. Cocolios, V. Fedoseev, R. Heinke, T. Kieck, B. Marsh, P. Naubereit, S. Rothe, T. Stora, D. Studer, P. Van Duppen, K. Wendt
    Published in: Hyperfine Interactions, issue 238/1, 2017.  ISSN: 0304-3843
    DOI: 10.1007/s10751-017-1406-x
  • The TwinEBIS setup: Machine description
    Author(s): M. Breitenfeldt, R. Mertzig, J. Pitters, A. Shornikov, F. Wenander
    Published in: Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, issue 856, 2017. Page(s) 139-146.  ISSN: 0168-9002
    DOI: 10.1016/j.nima.2016.12.037
  • A high-compression electron gun for C 6+ production: concept, simulations and mechanical design
    Author(s): Robert Mertzig, M. Breitenfeldt, S. Mathot, J. Pitters, A. Shornikov, F. Wenander
    Published in: Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, issue 859, 2017. Page(s) 102-111.  ISSN: 0168-9002
    DOI: 10.1016/j.nima.2016.12.036
  • Cardiac Radionuclide Imaging in Rodents: A Review of Methods, Results, and Factors at Play
    Author(s): Francesco Cicone, David Viertl, Ana Maria Quintela Pousa, Thibaut Denoël, Silvano Gnesin, Francesco Scopinaro, Marie-Catherine Vozenin, John O. Prior
    Published in: Frontiers in Medicine, issue 4, 2017. Page(s) 35.  ISSN: 2296-858X
    DOI: 10.3389/fmed.2017.00035

Coordinator

EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH
Switzerland

EU contribution: EUR 795 680,28


ROUTE DE MEYRIN CERN
1211 GENEVA 23
Switzerland
Activity type: Research Organisations

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Participants

THE UNIVERSITY OF MANCHESTER
United Kingdom

EU contribution: EUR 273 287,88


OXFORD ROAD
M13 9PL MANCHESTER
United Kingdom
Activity type: Higher or Secondary Education Establishments

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JOHANNES GUTENBERG-UNIVERSITAT MAINZ
Germany

EU contribution: EUR 249 216,48


SAARSTRASSE 21
55122 MAINZ
Germany
Activity type: Higher or Secondary Education Establishments

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Advanced Accelerator Applications
France

EU contribution: EUR 262 875,60


Rue Diesel 20
01630 Saint Genis Pouilly
France
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)

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INSTITUTO SUPERIOR TECNICO
Portugal

EU contribution: EUR 476 712,72


AVENIDA ROVISCO PAIS 1
1049-001 LISBOA
Portugal
Activity type: Higher or Secondary Education Establishments

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FONDAZIONE CENTRO NAZIONALE DI ADROTERAPIA ONCOLOGICA
Italy

EU contribution: EUR 258 061,32


STRADA CAMPEGGI 53
27100 PAVIA PV
Italy
Activity type: Research Organisations

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KATHOLIEKE UNIVERSITEIT LEUVEN
Belgium

EU contribution: EUR 250 560


Oude Markt 13
3000 LEUVEN
Belgium
Activity type: Higher or Secondary Education Establishments

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LEMER PAX
France

EU contribution: EUR 262 875,60


3.RUE DE L'EUROPE
44472 CARQUEFOU
France
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)

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Partner organisations

CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS
Switzerland
RUE DU BUGNON 21
1005 LAUSANNE
Switzerland
Activity type: Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)

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LES HOPITAUX UNIVERSITAIRES DE GENEVE
Switzerland
RUE GABRIELLE PERRET GENTIL 4
1205 GENEVE 14
Switzerland
Activity type: Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)

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ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
Switzerland
BATIMENT CE 3316 STATION 1
1015 LAUSANNE
Switzerland
Activity type: Higher or Secondary Education Establishments

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EBG (Entwicklungs- und Betriebsgesellschaft) MedAustron GmbH
Austria
Marie Curie-Strasse 5
2700 Wiener Neustadt
Austria
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)

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GROUPEMENT INTERET PUBLIC ARRONAX
France
RUE ARONNAX 1
44817 SAINT HERBLAIN
France
Activity type: Research Organisations

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INSTITUT MAX VON LAUE - PAUL LANGEVIN
France
71 AVENUE DES MARTYRS
38000 GRENOBLE
France
Activity type: Research Organisations

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Isis Innovation Ltd
United Kingdom
Oxford
United Kingdom
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)

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