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IN-Silico trials for treatment of acute Ischemic STroke

Deliverables

Finite element meshes of patient specific clot and vessel geometries

Finite element meshes of patient specific clot and vessel geometries

Quality Assurance Plan

Quality Assurance Plan to manage the quality control including a detailed risk analysis and contingency planning

Project Handbook

Project Handbook to ensure consistent implementation of the management

Implementation of model of microvascular damage

Implementation of model of microvascular damage

Data Management Plan template

Data Management Plan template

Initial report on dissemination, exploitation and sustainability plan

Initial report on dissemination, exploitation and sustainability plan with a detailed plan and schedule for all dissemination, communication, and exploitation activities. The plan will be delivered in M3, and updated to coincide with reporting period Note: All the tasks and deliverables depicted in this WP will be implemented taking into account the best practices in Data Management (WP1) and the template for Data Management Plan (D1.6)

Periodic reporting

Periodic technical reports and periodic financial and ethical reports for the EC. Report is due month 20

An in silico clinical stroke trial computing environment

An in silico clinical stroke trial computing environment

First report on models for thrombosis and thrombolysis and combined model describing the models and performed experiments

First report on models for thrombosis and thrombolysis and combined model describing the models and performed experiments. This deliverables is not just a report, but will also deliver the associated models as simulation software (e.g. to WP6).

Consortium Agreement

Consortium Agreement

First version of a virtual population of stroke patients (Module I)

First version of a virtual population of stroke patients (Module I)

First report on dissemination, communication and sustainability

First dissemination, communication and sustainability report, with a review of events dissemination, communication, and exploitation results including an update of dissemination, communication, and exploitation action plan Note: All the tasks and deliverables depicted in this WP will be implemented taking into account the best practices in Data Management (WP1) and the template for Data Management Plan (D1.6)

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Publications

Structural analysis of ischemic stroke thrombi: histological indications for therapy resistance

Author(s): Senna Staessens, Frederik Denorme, Olivier François, Linda Desender, Tom Dewaele, Peter Vanacker, Hans Deckmyn, Karen Vanhoorelbeke, Tommy Andersson, Simon F De Meyer
Published in: Haematologica, Issue May 2019;104, 2019, ISSN 0390-6078