Objective
Innovative and effective biological therapies exist to treat non-communicable inflammatory skin diseases (ncISD). However, diagnostic guidance when and how to use them is imprecise; no substantial innovation was made for decades. Due to this lack of innovation, high socio-economic costs are caused by ineffective unguided treatment – a waste of resources. Existing ERC research aims at establishing individualised medicine in ncISD (IMCIS, grant agreement 676858). First success is a biomarker to distinguish psoriasis from eczema. Due to disease heterogeneity, these two ncISD cannot be distinguished in 10% of all cases with current gold standard diagnostics. Treating patients with the wrong therapy as a consequence of mis-diagnosis is inefficient and might even be harmful. This PoC proposal follows the path of IMCIS and closes the gap between ERC research and a prototype device of a point-of-care microfluidic testing device to distinguish psoriasis and eczema based on their molecular signature (peLabDisk). The proposal is feasible, as there is a high level of expertise created by joint forces of researchers of the Technical University of Munich and Hahn-Schickard providing extensive competence in the development, construction and manufacturing of microfluidic cartridges for medical applications. The project plan consists of well-defined work packages and milestones. Furthermore, success of the individual work packages is supervised by experienced experts (TUM Entrepeneurship). This PoC proposal is not the end – there is a clear roadmap and a detailed strategy for the post-PoC phase including potential end-user network and supported foundation of a spin-off company. peLabDisk represents the first approach of molecular diagnostics in the field that is easy-to-handle, robust and valid, as well as economic. It is superior to current gold standard diagnostics. Furthermore, peLabDisk is a use-case for point-of-care molecular diagnostics in complex inflammatory diseases.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- medical and health sciences health sciences inflammatory diseases
- medical and health sciences clinical medicine dermatology
- medical and health sciences basic medicine immunology immunotherapy
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
ERC-POC - Proof of Concept Grant
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) ERC-2017-PoC
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
81675 MUENCHEN
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.