Project description DEENESFRITPL Integrating Big Data for predictive computational models in personalised medicine Technological advances in biomedical sciences over the years have led to the production of a large amount of omics, imaging, health and lifestyle data. Although this Big Data holds immense potential for clinical applications, it has not been successfully exploited. The key objective of the EU-funded EU-STANDS4PM project is to establish a pan-European expert forum for evaluating existing standards and developing universal guidelines for the harmonised integration of heterogeneous health data for in silico methodologies. The project's efforts will assist in the provision of guidelines for verifying and validating predictive computational models that can be applied in personalised medicine approaches. Show the project objective Hide the project objective Objective The capacity to generate data in Life Sciences and health research with modern omics and imaging technologies has increased many orders of magnitude in the last decade. In combination with patient/personal derived data such as electronic health records, patient registries and -databases, as well as life style information this Big Data holds an immense potential for clinical applications, especially for in silico personalized medicine approaches. However, and despite the ever progressing technological advances in producing data, the exploitation of Big Data information to generate new knowledge for medical benefits, while guaranteeing data privacy and security, is lacking behind its full potential. A reason for this obstacle is the inherent heterogeneity of Big Data and the lack of broadly accepted standards that allow interoperable integration of heterogeneous health data to perform analysis and interpretation for predictive in silico modelling approaches in health research such as personalized medicine. Further obstacles are legal issues surrounding the use of personal data. To overcome these obstacles, we will establish a pan-European Expert forum with two main objectives: (i) to assess and evaluate national standardization strategies for interoperable health data integration (such as omics-, disease-focused-, clinical-/treatment- or healthcare- and socioeconomic-/lifestyle-data) as well as data-driven in silico modelling approaches and (ii) to harmonize and develop universal (cross-border) standards as well as recommendations for in silico methodologies applied in personalized medicine approaches. This pan-European Expert Forum —the EU-STANDS4PM consortium— has the overarching aim to bundle transnational standardization guidelines for in silico methodologies in transnational and clinical research to unfold the potential of personalized medicine. Fields of science natural sciencescomputer and information sciencesdatabasesnatural sciencescomputer and information sciencesdata sciencebig datamedical and health scienceshealth sciencespersonalized medicine Keywords standards data integration in silico modelling personalized medicine European framework Programme(s) H2020-EU.3.1. - SOCIETAL CHALLENGES - Health, demographic change and well-being Main Programme H2020-EU.3.1.6. - Health care provision and integrated care Topic(s) SC1-HCO-02-2018 - Data integration and data-driven in-silico models for enabling personalised medicine - a European standardization framework Call for proposal H2020-SC1-BHC-2018-2020 See other projects for this call Sub call H2020-SC1-2018-Single-Stage-RTD Funding Scheme CSA - Coordination and support action Coordinator FORSCHUNGSZENTRUM JULICH GMBH Net EU contribution € 489 590,00 Address Wilhelm johnen strasse 52428 Julich Germany See on map Region Nordrhein-Westfalen Köln Düren Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Participants (16) Sort alphabetically Sort by Net EU contribution Expand all Collapse all BAYER AKTIENGESELLSCHAFT Participation ended Germany Net EU contribution € 7 888,64 Address Kaiser-wilhelm-allee 1 51373 Leverkusen See on map Region Nordrhein-Westfalen Köln Leverkusen, Kreisfreie Stadt Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL Germany Net EU contribution € 54 493,75 Address Olshausenstrasse 40 24118 Kiel See on map Region Schleswig-Holstein Schleswig-Holstein Kiel, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM Netherlands Net EU contribution € 37 500,00 Address Dr molewaterplein 40 3015 GD Rotterdam See on map Region West-Nederland Zuid-Holland Groot-Rijnmond Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 EUROPEAN MOLECULAR BIOLOGY LABORATORY Germany Net EU contribution € 150 230,00 Address Meyerhofstrasse 1 69117 Heidelberg See on map Region Baden-Württemberg Karlsruhe Heidelberg, Stadtkreis Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 HITS GGMBH Germany Net EU contribution € 190 000,00 Address Schloss wolfsbrunnenweg 35 69118 Heidelberg See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Baden-Württemberg Karlsruhe Heidelberg, Stadtkreis Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 FEDERAL AGENCY FOR MEDICINES AND HEALTH PRODUCTS Belgium Net EU contribution € 60 000,00 Address Avenue galile 5/03 1210 Sint-joost-ten-node See on map Region Région de Bruxelles-Capitale/Brussels Hoofdstedelijk Gewest Région de Bruxelles-Capitale/ Brussels Hoofdstedelijk Gewest Arr. de Bruxelles-Capitale/Arr. Brussel-Hoofdstad Activity type Research Organisations Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 DIN DEUTSCHES INSTITUT FUER NORMUNG EV Germany Net EU contribution € 67 500,00 Address Burggrafenstrasse 6 10787 Berlin See on map Region Berlin Berlin Berlin Activity type Other Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 KAROLINSKA INSTITUTET Sweden Net EU contribution € 61 875,00 Address Nobels vag 5 17177 Stockholm See on map Region Östra Sverige Stockholm Stockholms län Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 QIAGEN GMBH Germany Net EU contribution € 22 500,00 Address Qiagen strasse 1 40724 Hilden See on map Region Nordrhein-Westfalen Düsseldorf Mettmann Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSITY COLLEGE LONDON GB Net EU contribution € 225 625,00 Address Gower street WC1E 6BT London See on map Region London Inner London — West Camden and City of London Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 KOBENHAVNS UNIVERSITET Denmark Net EU contribution € 319 810,00 Address Norregade 10 1165 Kobenhavn See on map Region Danmark Hovedstaden Byen København Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD GB Net EU contribution € 110 787,50 Address Wellington square university offices OX1 2JD Oxford See on map Region South East (England) Berkshire, Buckinghamshire and Oxfordshire Oxfordshire Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSITA DEGLI STUDI DI PARMA Italy Net EU contribution € 78 750,00 Address Via universita 12 43100 Parma See on map Region Nord-Est Emilia-Romagna Parma Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSITAET ROSTOCK Germany Net EU contribution € 42 500,00 Address Universitatsplatz 1 18055 Rostock See on map Region Baden-Württemberg Stuttgart Stuttgart, Stadtkreis Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 VILNIAUS UNIVERSITETAS Lithuania Net EU contribution € 63 750,00 Address Universiteto g. 3 01513 Vilnius See on map Region Lietuva Sostinės regionas Vilniaus apskritis Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSITAETSKLINIKUM AACHEN Germany Net EU contribution € 59 611,36 Address Pauwelsstrasse 30 52074 Aachen See on map Region Nordrhein-Westfalen Köln Städteregion Aachen Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00