Skip to main content

A European standardization framework for data integration and data-driven in silico models for personalized medicine

Objective

The capacity to generate data in Life Sciences and health research with modern omics and imaging technologies has increased many orders of magnitude in the last decade. In combination with patient/personal derived data such as electronic health records, patient registries and -databases, as well as life style information this Big Data holds an immense potential for clinical applications, especially for in silico personalized medicine approaches. However, and despite the ever progressing technological advances in producing data, the exploitation of Big Data information to generate new knowledge for medical benefits, while guaranteeing data privacy and security, is lacking behind its full potential. A reason for this obstacle is the inherent heterogeneity of Big Data and the lack of broadly accepted standards that allow interoperable integration of heterogeneous health data to perform analysis and interpretation for predictive in silico modelling approaches in health research such as personalized medicine. Further obstacles are legal issues surrounding the use of personal data. To overcome these obstacles, we will establish a pan-European Expert forum with two main objectives: (i) to assess and evaluate national standardization strategies for interoperable health data integration (such as omics-, disease-focused-, clinical-/treatment- or healthcare- and socioeconomic-/lifestyle-data) as well as data-driven in silico modelling approaches and (ii) to harmonize and develop universal (cross-border) standards as well as recommendations for in silico methodologies applied in personalized medicine approaches. This pan-European Expert Forum —the EU-STANDS4PM consortium— has the overarching aim to bundle transnational standardization guidelines for in silico methodologies in transnational and clinical research to unfold the potential of personalized medicine.

Field of science

  • /natural sciences/computer and information sciences/databases
  • /natural sciences/computer and information sciences/data science/big data

Call for proposal

H2020-SC1-2018-Single-Stage-RTD
See other projects for this call

Funding Scheme

CSA - Coordination and support action

Coordinator

FORSCHUNGSZENTRUM JULICH GMBH
Address
Wilhelm Johnen Strasse
52428 Julich
Germany
Activity type
Research Organisations
EU contribution
€ 512 465

Participants (15)

BAYER AKTIENGESELLSCHAFT
Germany
EU contribution
€ 67 500
Address
Kaiser-wilhelm-allee 1
51373 Leverkusen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL
Germany
EU contribution
€ 54 493,75
Address
Olshausenstrasse 40
24118 Kiel
Activity type
Higher or Secondary Education Establishments
ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Netherlands
EU contribution
€ 37 500
Address
Dr Molewaterplein 40
3015 GD Rotterdam
Activity type
Higher or Secondary Education Establishments
EUROPEAN MOLECULAR BIOLOGY LABORATORY
Germany
EU contribution
€ 189 430
Address
Meyerhofstrasse 1
69117 Heidelberg
Activity type
Research Organisations
HITS GGMBH
Germany
EU contribution
€ 190 000
Address
Schloss Wolfsbrunnenweg 35
69118 Heidelberg
Activity type
Research Organisations
FEDERAL AGENCY FOR MEDICINES AND HEALTH PRODUCTS
Belgium
EU contribution
€ 30 000
Address
Place Victor Horta 40/40
1060 Brussels
Activity type
Research Organisations
DIN DEUTSCHES INSTITUT FUER NORMUNG E.V.
Germany
EU contribution
€ 67 500
Address
Burggrafenstrasse 6
10787 Berlin
Activity type
Other
KAROLINSKA INSTITUTET
Sweden
EU contribution
€ 61 875
Address
Nobels Vag 5
17177 Stockholm
Activity type
Higher or Secondary Education Establishments
QIAGEN GMBH
Germany
EU contribution
€ 22 500
Address
Qiagen Strasse 1
40724 Hilden
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
UNIVERSITY COLLEGE LONDON
United Kingdom
EU contribution
€ 175 000
Address
Gower Street
WC1E 6BT London
Activity type
Higher or Secondary Education Establishments
KOBENHAVNS UNIVERSITET
Denmark
EU contribution
€ 399 610
Address
Norregade 10
1165 Kobenhavn
Activity type
Higher or Secondary Education Establishments
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
United Kingdom
EU contribution
€ 88 287,50
Address
Wellington Square University Offices
OX1 2JD Oxford
Activity type
Higher or Secondary Education Establishments
UNIVERSITA DEGLI STUDI DI PARMA
Italy
EU contribution
€ 60 000
Address
Via Universita 12
43100 Parma
Activity type
Higher or Secondary Education Establishments
UNIVERSITAET ROSTOCK
Germany
EU contribution
€ 22 500
Address
Universitatsplatz 1
18055 Rostock
Activity type
Higher or Secondary Education Establishments
VILNIAUS UNIVERSITETAS
Lithuania
EU contribution
€ 63 750
Address
Universiteto G. 3
01513 Vilnius
Activity type
Higher or Secondary Education Establishments