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From Skin to Skeleton: Revolutionary Contactless and Non-Ionizing 3D Digital Diagnosis and Monitoring of Spinal Disorders in Adolescents

Project description

Safer 3D scoliosis diagnosis

Adolescent idiopathic scoliosis (AIS) represents 80 % of cases of scoliosis, a medical condition in which a person’s spine has a sideways curve. Existing diagnostic methods require radiographic exposure. A new generation of optical techniques that use 3D digitalised surface of the patient’s back to assess the curvature of the spine and deformity evolution are considered a reliable alternative. Nevertheless, these digital techniques cannot estimate the internal parameters of AIS and ignore the 3D complexity of the internal spinal structure. The EU-funded ScolioSIM project proposes a markerless computer-based optical solution to generate a 3D reproduction of the patient-specific spine and diagnose internal and external biomechanical features and parameters of AIS, avoiding radiographic exposures.

Objective

Scoliosis is a 3D musculoskeletal disorder of the spine that affects the quality of life and physical ability of patients. Almost 80% of all cases comprise of adolescent idiopathic scoliosis (AIS) with an estimated prevalence of 36 million new patients worldwide by 2050. The drawback of current diagnostic methods in AIS assessment is their harmful effect, especially due to the multiple radiographic exposures required for monitoring disease progression. A new generation of optical techniques for estimating curvature of the spine and evaluating deformity-related changes from a 3D digitalized surface of the patient’s back are considered as an alternative to ionizing methods. However, none of these non-ionizing approaches have been applied to calculate the internal parameters of AIS and neglect the 3D complexity of the internal spinal structure. The proposed action aims to test and improve a markerless computer-aided optical solution (ScolioSIM1.0) that can generate a 3D model of the patient-specific scoliotic spine, and to reliably predict internal and external biomechanical characteristics and parameters of AIS without exposing patients to ionizing radiation. This process includes the development of a novel computational algorithm for online monitoring of AIS after treatment and regular follow-ups (ScolioSIM2.0) and its integration into the first multi-modular web-based platform (ScolioMedIS). The fellowship involves an experienced candidate, Dr Saša Ćuković, from UniKg, Serbia to conduct this multidisciplinary and innovative project at ETH Zurich in the group of Prof. Dr William R. Taylor. The action also provides opportunities for two-way knowledge transfer in the field of musculoskeletal modelling, computational biomechanics and new ICT methods thus, presenting a clear target for the fellow to reach professional independence through research and intense training, and for the host to broaden research domains specifically in the field of spinal disorder biomechanics.

Fields of science (EuroSciVoc)

Programme(s)

Topic(s)

Funding Scheme

MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)

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Call for proposal

(opens in new window) H2020-MSCA-IF-2019

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Coordinator

EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
Net EU contribution
€ 191 149,44
Address
Raemistrasse 101
8092 Zuerich
Switzerland
Region
Schweiz/Suisse/Svizzera Zürich Zürich
Activity type
Higher or Secondary Education Establishments
Links
Total cost
€ 191 149,44