Project description
Understanding how the gut microbiota fights foodborne pathogens
Foodborne and waterborne diseases remain a global public health challenge, causing 23 million illnesses in the European region and 5 000 deaths per year. Focusing on the medical side of prevention, the EU-funded COL_RES project will form a network to study the mechanisms by which the gut microbiota protects against serious Salmonella, E. coli, Listeria, Citrobacter, Campylobacter and other foodborne pathogens. This will help researchers identify next-generation probiotics that can protect against multiple infectious agents. It will also identify overlapping mechanisms by which members of the gut microbiota provide a barrier to infection through the phenomenon of colonisation resistance. By forging intersectoral industry-academia secondments, the network will provide training for early stage researchers.
Objective
The COL_RES network comprises a world-leading group of investigators that will investigate the mechanisms by which the gut microbiota protects against serious foodborne pathogens (Salmonella, E. coli, Listeria, Citrobacter and Campylobacter) and lead to the identification of next generation probiotics that can protect against multiple infectious agents. Through intersectoral industry-academia secondments the network will provide state-of-the-art training for early stage researchers (ESR) preparing them for problem solving and entrepreneurial roles in industry and society and underpinning cutting-edge research in infectious disease in the EU. Food and water borne diseases cause 23 million illnesses in the European region with 5000 deaths per annum and represent an increasing challenge to the health of the EU and global population. Through studying different pathogens using shared approaches the COL_RES network will undertake a network-wide approach to identify overlapping mechanisms by which members of the gut microbiota provide a barrier to infection through the phenomenon of Colonization Resistance. The work will utilise a systems-based approach by exploiting existing research models at world-leading laboratories combined with phageomics, metabolomics and bioinformatics to generate multi-omics data that will uncover both pathogen-specific and shared mechanisms by which the gut microbiota protects against foodborne pathogens. The work will inform the selection and testing of specific next-generation probiotic candidates that can protect against foodborne infections, with potential for further development by our industry partners. Thus, the network will enhance training through world-leading research via cross-sectoral industry secondments in an actively entrepreneurial environment.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.1. - Fostering new skills by means of excellent initial training of researchers
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-ITN - Marie Skłodowska-Curie Innovative Training Networks (ITN)
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-ITN-2020
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
T12 YN60 Cork
Ireland
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.