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BABOTS: The design and control of small swarming biological animal robots

Project description

A new approach to biorobotics that could benefit farmers

Scientists are embarking on a project to develop biological animal robots (BABots). While this may sound like science fiction, it is a real and ambitious scientific endeavour that would allow small animals with genetically modified nervous systems to carry out a range of behaviours beyond their natural capabilities. The EU funded BABOTS project will design the first BABot system. It will be implemented in Caenorhabditis elegans, a nematode worm, which will be programmed to act collectively to detect and attack pathogens in an agricultural setting. BABOTS will genetically modify individual worm gene circuits and study collective behaviour in engineered worms to develop a theory of heterogeneity-based swarm control.

Objective

We aim to establish a fundamentally new technology of Biological Animal roBots (BABots), consisting of small animals with a genetically modified nervous system, enabling the execution of a desired repertoire of behaviors beyond their natural abilities. We will implement the first BABot system in C. elegans, a 1 mm long nematode worm. These worms will be programmed to act as a collective, and to detect, locate and attack invading pathogens in an agricultural setting. Being 100% biological, BABots are highly compatible with the natural environment, self-producible, and fully degradable. They will also be agile and highly sensitive to surrounding signals. To control BABot behavior, we will genetically insert specific new synaptic connections and synthetic gene circuits in C. elegans to produce artificial aggregation, dynamic sensorimotor switching and other functional building blocks. To ensure a safe and controlled deployment, we will genetically implement a multi-layered biocontainment apparatus. To gain tighter control over the BABot collective behavior, we will exploit heterogeneity in the population, blending, for example, leader and follower BABots, based on their differential access to information. The science behind this innovative technology includes a synthetic neurobiological approach to modifying individual worm behavior, the study of collective behavior in engineered worms, and the development of a theory of heterogeneity-based swarm control. We also dedicate a substantial effort to establish a firm and effective safety, ethical and regulatory framework, under which current and future BABots can be developed. This project will generate a radically new approach to bio-robotics that could contribute to precision agriculture, industry and medicine. Improving over a previous proposal, we significantly enhanced (i) the methodology, (ii) the safety and ethical aspects, and (iii) the demonstration and exploitation by implementation in an agricultural setting.

Fields of science (EuroSciVoc)

Keywords

Programme(s)

Topic(s)

Funding Scheme

HORIZON-EIC - HORIZON EIC Grants

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Call for proposal

(opens in new window) HORIZON-EIC-2022-PATHFINDEROPEN-01

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Coordinator

UNIVERSITE DE NAMUR
Net EU contribution
€ 600 900,00
Address
RUE DE BRUXELLES 61
5000 Namur
Belgium
Region
Région wallonne Prov. Namur Arr. Namur
Activity type
Higher or Secondary Education Establishments
Links
Total cost
€ 600 900,00

Participants (5)