Artificial Intelligence-driven, Decentralized Production for Advanced Therapies in the Hospital

Risultati finali

Stakeholder centric design principles ensuring trust and acceptance
Results dissemination campaign plan
Societal Guide for implementing Smart Manufacturing Hospitals

Data management plan

Pubblicazioni

Elaborating the potential of Artificial Intelligence in automated CAR-T cell manufacturing

Autori: Niklas Bäckel, Tamás Kis, David F. Nettleton, Joseph R. Egan, John J. L. Jacobs, Dennis Grunert, Robert H. Schmitt
Pubblicato in: Frontiers in Molecular Medicine, 2023
Editore: Frontiers
DOI: 10.3389/fmmed.2023.1250508

How can digitalisation and AI improve CAR-T cell manufacturing?

Autori: Simon Hort
Pubblicato in: Advanced Therapies Europe 2023, 2023
Editore: Fraunhofer Publica
DOI: 10.24406/publica-2433

Process Development and Manufacturing: Impact Of Xeno-Free And Serum Free Medium Formulations For Car-T Cell Manufacturing

Autori: P. Silva Couto, P. Springuel, Q.A. Rafiq
Pubblicato in: 2023
Editore: Elsevier
DOI: 10.1016/s1465-3249(23)00527-3

AIDPATH - Modular Approach to AI-Enabled CAR-T Cell Manufacturing

Autori: Erkens, Frederik
Pubblicato in: Numero 1, 2022
Editore: International Forum on Cell Manufacturing & Engineeing 2022
DOI: 10.24406/publica-574

Optimising Perfusion Parameters Using Quality By Design For The Intensified Production Of Car T Cells In A Single-Use Automated Stirred-Tank Bioreactor

Autori: P. Springuel, T. Hood, F. Slingsby, N. Bevan, W. Geis, V. Sandner, T. Schmidberger, J. Hengst, N. Dianat, Q.A. Rafiq
Pubblicato in: 2023
Editore: Elsevier
DOI: 10.1016/s1465-3249(23)00528-5

How can digitalization and automation enable large-scale application of CAR-T cell therapies?

Autori: Frederik Erkens
Pubblicato in: 2023
Editore: Fraunhofer publica
DOI: 10.24406/publica-2040

Trust in and Acceptance of Artificial Intelligence Applications in Medicine: Mixed Methods Study

Autori: Daria Shevtsova 1, 2 Author Orcid Image ; Anam Ahmed 1 Author Orcid Image ; Iris W A Boot 1 Author Orcid Image ; Carmen Sanges 3 Author Orcid Image ; Michael Hudecek 3 Author Orcid Image ; John J L Jacobs 4 Author Orcid Image ; Simon Hort 5 Author Orcid Image ; Hubertus J M Vrijhoef 1 Author Orcid Image
Pubblicato in: JMIR Human Factors, 2024, ISSN 2292-9495
Editore: JMIR Publications
DOI: 10.2196/47031

Smart Sensor Control and Monitoring of an Automated Cell Expansion Process

Autori: David F. Nettleton; Núria Marí-Buyé; Helena Marti-Soler; Joseph R. Egan; Simon Hort; David Horna; Miquel Costa; Elia Vallejo Benítez-Cano; Stephen Goldrick; Qasim A. Rafiq; Niels König; Robert H. Schmitt; Aldo R. Reyes
Pubblicato in: Sensors, 2023, ISSN 1424-8220
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/s23249676

Toward Rapid, Widely Available Autologous CAR-T Cell Therapy – Artificial Intelligence and Automation Enabling the Smart Manufacturing Hospital

Autori: Hort S, Herbst L, Bäckel N, Erkens F, Niessing B, Frye M, König N, Papantoniou I, Hudecek M, Jacobs JJL and Schmitt RH
Pubblicato in: Frontiers in Medicine, 2022, ISSN 2296-858X
Editore: Frontiers Media
DOI: 10.3389/fmed.2022.913287

Towards Automated Car-T Cell Manufacturing - Keeping up with Technological Advancement

Autori: Laura Herbst
Pubblicato in: 2023
Editore: Fraunhofer publica
DOI: 10.1016/s1465-3249(22)00437-6

Digital transformation of CAR-T cell therapy – challenges and potential for Industry 4.0

Autori: Simon Hort , Carmen Sanges , John J.L. Jacobs , Michael Hudecek , Robert H. Schmitt
Pubblicato in: Procedia CIRP International Conference on Manufacturing Systems 2023, Numero 120, 2023, ISSN 2212-8271
Editore: Elsevier BV
DOI: 10.1016/j.procir.2023.09.121

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