Risultati finali Open Research Data Pilot (6) Imaging of HEV-infected ex vivo porcine precision cut liver slices Structural differences in HEV-infected pig and human cell lines Correlation of the kinetics normal cell homeostasis of viral antigen and genomic RNA with restoration of Correlation of the kinetics of viral antigen and genomic RNA with restoration of normal cell homeostasis 3D model of infected lung epithelial cell Calibration table of x-ray absorption coefficient for adherent cells. The table will provide calibration value to translated x-ray linear absorption coefficient obtained with lab-based SXM with respect to the synchrotron source for EM grid sample holders and limited angle tomography. Calibration table of x-ray absorption coefficient for suspended cells. The table will provide calibration value to translated x-ray linear absorption coefficient obtained with lab-based SXM with respect to the synchrotron source for cells in suspension and full rotation tomography. Demonstrators, pilots, prototypes (1) Fully tested in-line FM Fully validated FM as indicated through bench tests and inline imaging of fluorescent nanospheres Pubblicazioni Peer reviewed articles (8) Three-Dimensional Remodeling of SARS-CoV2-Infected Cells Revealed by Cryogenic Soft X-ray Tomography Autori: Victoria Castro, Ana Joaquina Pérez-Berna, Gema Calvo, Eva Pereiro*, and Pablo Gastaminza Pubblicato in: ACS Nano, Issue 2023, 17, 22, 2023, Page(s) 22708–22721, ISSN 1936-0851 Editore: American Chemical Society DOI: 10.1021/acsnano.3c07265 Monitoring reversion of hepatitis C virus-induced cellular alterations by direct-acting antivirals using cryo soft X-ray tomography and infrared microscopy Autori: Ana J. Pérez-Berná; Nuria Benseny-Cases; María José Cubillas Rodríguez; Ricardo Valcárcel; José L. Carrascosa; Pablo Gastaminza; Eva Pereiro Pubblicato in: Acta Crystallographica Section D: Structural Biology, Issue 1, 2021, ISSN 2059-7983 Editore: IUCr DOI: 10.1107/s2059798321009955 Infection-induced chromatin modifications facilitate translocation of herpes simplex virus capsids to the inner nuclear membrane Autori: Vesa Aho ,Sami Salminen, Salla Mattola, Alka Gupta, Felix Flomm, Beate Sodeik, Jens B. Bosse, Maija Vihinen-Ranta Pubblicato in: PLOS PATHOGENS, 2021, ISSN 1553-7366 Editore: Public Library of Science DOI: 10.1371/journal.ppat.1010132 Soft X-ray Tomography Reveals HSV-1-Induced Remodeling of Human B Cells Autori: Jian-Hua Chen,Bieke Vanslembrouck, Axel Ekman, Vesa Aho, Carolyn A. Larabell, Mark A. Le Gros, Maija Vihinen-Ranta, Venera Weinhardt Pubblicato in: Viruses, 2022, ISSN 1999-4915 Editore: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/v14122651 Compact Cell Imaging Device (CoCID) to provide insights into the cellular origins of viral infections Autori: Kenneth Fahy, Venera Weinhardt, Maija Vihinen-Ranta, Nicola Fletcher, Dunja Skoko, Eva Pereiro, Pablo Gastaminza, Ralf Bartenschlager, Dimitri Scholz, Axel Ekman, Tony McEnroe Pubblicato in: Journal of Physics: Photonics, 2021, ISSN 2515-7647 Editore: IOP Publishing DOI: 10.1088/2515-7647/abfc5a A protocol for full-rotation soft X-ray tomography of single cells Autori: Jian-Hua Chen, Bieke Vanslembrouck, Valentina Loconte, Axel Ekman, Mirko Cortese, Ralf Bartenschlager, Gerry McDermott, Carolyn A. Larabell, Mark A. Le Gros, and Venera Weinhardt Pubblicato in: STAR Protocols, 2022, ISSN 2666-1667 Editore: Elsevier DOI: 10.1016/j.xpro.2022.101176 Using soft X-ray tomography for rapid whole-cell quantitative imaging of SARS-CoV-2-infected cells. Autori: Valentina Loconte; Valentina Loconte; Jian-Hua Chen; Jian-Hua Chen; Mirko Cortese; Axel Ekman; Mark A. Le Gros; Mark A. Le Gros; Carolyn A. Larabell; Carolyn A. Larabell; Ralf Bartenschlager; Ralf Bartenschlager; Venera Weinhardt; Venera Weinhardt Pubblicato in: Cell Reports Methods, Issue 2, 2021, ISSN 2667-2375 Editore: Cell Press DOI: 10.1016/j.crmeth.2021.100117 Imaging of Virus-Infected Cells with Soft X-ray Tomography Autori: Damià Garriga, Francisco Javier Chichón, Bárbara M. Calisto, Diego S. Ferrero, Pablo Gastaminza, Eva Pereiro and Ana Joaquina Pérez-Berna Pubblicato in: Viruses, Issue Monthly, 2021, ISSN 1999-4915 Editore: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/v13112109 È in corso la ricerca di dati su OpenAIRE... Si è verificato un errore durante la ricerca dei dati su OpenAIRE Nessun risultato disponibile
