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CORDIS - Resultados de investigaciones de la UE
CORDIS

In-silico Development- and Clinical-Trial-Platform for Testing in-situ Tissue Engineered Heart Valves

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

EU Periodic Report 1 (se abrirá en una nueva ventana)

obligatory periodic project status reporting to EUfollowing the end of each reporting period the functionality of periodic reporting will be activated While the periodic reporting session is open in the grant management system each participant will be able tocomplete online their own Financial Statement and the financial report of their Third Parties if any including the explanations on the use of resources upload the narrative free text part part B of the periodic technical report as a pdf document

Scaffold Material Model ABAQUS Validation Report (se abrirá en una nueva ventana)

Validation report describing the conducted validation tests for the developed Abaqus UMAT/VUMAT code / material model

Scaffold Material Model ABAQUS Verification Report (se abrirá en una nueva ventana)

Verification report describing the conducted code verification tests for the developed Abaqus UMATVUMAT code

Patient-specific Xeltis-PV validation & UQ report (se abrirá en una nueva ventana)

Model validation & UQ by comparing computed data with available clinical data sets.

Benchmark TAVI FSI-model - VVUQ report (se abrirá en una nueva ventana)

Verification/Validation & UQ report for the Benchmark TAVI FSI-model. This report covers the FSI model.

EU Periodic Report 2 (se abrirá en una nueva ventana)

obligatory periodic project status reporting to EUfollowing the end of each reporting period the functionality of periodic reporting will be activated. While the periodic reporting session is open in the grant management system, each participant will be able to:complete on-line their own Financial Statement (and the financial report of their Third Parties, if any) including the explanations on the use of resources; upload the narrative, free text part (part B) of the periodic technical report as a pdf document

Dissemination Plan Update (se abrirá en una nueva ventana)
Patient-specific Xeltis-PV calibration & verification report (se abrirá en una nueva ventana)

Patient-specific calibration & verification simulations performed on 15 data sets. Comparison with available clinical data will be used to fine-tune the models.

Xeltis-PV FE-model - VVUQ report (se abrirá en una nueva ventana)

Verification/Validation & UQ report for the Xeltis-PV FE-model. This report covers only the structural part of the model. FSI is not part of this report

Scaffold Material Test Data & Test Report Ia (se abrirá en una nueva ventana)

Final test report about polymer scaffold material characterization program as conducted by Leartiker

Stent Material Evaluation and Calibration Report (se abrirá en una nueva ventana)

Test report on the material evaluation and calibration of Nitinol as used for TVAI systems

Data Management Plan (se abrirá en una nueva ventana)

Data Management Plans DMPs are a key element of good data management A DMP describes the data management life cycle for the data to be collected processed andor generated by a Horizon 2020 project As part of making research data findable accessible interoperable and reusable FAIR a DMP should include information on the handling of research data during after the end of the project what data will be collected processed andor generated which methodology standards will be applied whether data will be sharedmade open access and how data will be curated preserved including after the end of the projectA DMP is required for all projects participating in the extended ORD pilot unless they opt out of the ORD pilot However projects that opt out are still encouraged to submit a DMP on a voluntary basis

Scaffold Material Test Data & Test Report Id (se abrirá en una nueva ventana)

Final test report about polymer scaffold material characterization program as conducted by TUGraz

Dissemination Plan (se abrirá en una nueva ventana)
Patient specific Benchmark-TAVI validation & UQ report (se abrirá en una nueva ventana)

UQ & validation report based on 100 patient-specific simulations (previously prepared models). Comparison with clinical data sets.

Exploitation Plan (se abrirá en una nueva ventana)
Scaffold Material Fatigue Test Report (se abrirá en una nueva ventana)

Final report on the fatigue behavior of the polymeric scaffold material considering the need to provide fatigue stability until it is fully remodeled.

Scaffold Material Test UQ Report (se abrirá en una nueva ventana)

Test report on UQ of test results coming from Scaffold Material Test Data & Report 1a / 1b / 1c / 1d.

Scaffold Material Test Data & Test Report Ib (se abrirá en una nueva ventana)

Final test report about polymer scaffold material characterization program as conducted by KULeuven Soft Tissue Biomechancs

Patient specific Benchmark-TAVI calibration & verification report (se abrirá en una nueva ventana)

Patient-specific calibration & verification simulations performed on 20 patient data sets.Comparison of pre-TAVI & post-TAVI scenarios with available clinical data will be used to fine-tune the models.

Benchmark TAVI FE-model - VVUQ report (se abrirá en una nueva ventana)

Verification/Validation & UQ report for the Benchmark TAVI FE-model. This report covers only the structural part of the model. FSI is not part of this report

Project Management Plan (se abrirá en una nueva ventana)

Project Management Plan: classic project management document that covers all relevant items, such as in-scope / out-of-scope, time management, resource management, risk management, communication management etc. Items overlapping with Grant Agreement, Consortium Agreement, and Data Management will be referenced.

Scaffold Material Test Data & Test Report Ic (se abrirá en una nueva ventana)

Final test report about polymer scaffold material characterization program as conducted by Armines MINES Sainttienne Soft Tissue Biomechanics

Patient specific AV imaging data sets (130) (se abrirá en una nueva ventana)

Patient Data from Procurement, Digitisation, and Curation (ISMETT)Morphological and Physiological Data Collection and Classification

patient-specific Benchmark TAVI Repository (se abrirá en una nueva ventana)

developed & validated patient specific Benchmark TAVI model will be provided to public

ETR Constitutive Equations (se abrirá en una nueva ventana)

developed constitutive equations (material model) to describe the ETR process of the biodegradable polymeric scaffold material. Builds upon material model developed in WP1 & WP2

Publicaciones

Abstract: Novel bioresorbable carotid graft: experimental assessment through an animal model.

Autores: Hendrickx Amber
Publicado en: 2022
Editor: European Society of biomechanics

ABSTRACT: PARAMETER SENSITIVITY AND OPTIMIZATION OF THE MECHANO IMMUNO-DRIVEN MODEL OF ENDOGENOUS TISSUE RESTORATION.

Autores: Hadi Shirazi et al.
Publicado en: 2023
Editor: European Society of BIomechanics

ABSTRACT: NOVEL BIORESORBABLE PULMONARY VALVES: EXPERIMENTAL ASSESSMENT THROUGH AN ANIMAL TRIAL.

Autores: Hendrickx Amber
Publicado en: 2023
Editor: European Society of Biomechanics

Computational Modeling of Endogenous Tissue Restoration in Biodegradable Carotid Grafts

Autores: H. Shirazi, L. Maes, T. Vervenne, N. Famaey
Publicado en: 2024
Editor: ESB2024 congress

Computational Predictive Modeling of a Novel Pulmonary Valved Conduit

Autores: van Tunen, Rick
Publicado en: 2023
Editor: TU Delft

On the Material Constitutive Behavior of the Aortic Root in Patients with Transcatheter Aortic Valve Implantation (se abrirá en una nueva ventana)

Autores: Chiara Catalano, Tahir Turgut, Omar Zahalka, Nils Götzen, Stefano Cannata, Giovanni Gentile, Valentina Agnese, Caterina Gandolfo & Salvatore Pasta
Publicado en: Cardiovasc Eng Tech, 2023, ISSN 1869-4098
Editor: Cardiovasc Eng Tech
DOI: 10.1007/s13239-023-00699-7

Generation of a virtual cohort of TAVI patients for in silico trials: a statistical shape and machine learning analysis (se abrirá en una nueva ventana)

Autores: Roberta Scuoppo, Salvatore Castelbuono, Stefano Cannata, Giovanni Gentile, Valentina Agnese, Diego Bellavia, Caterina Gandolfo, Salvatore Pasta
Publicado en: Medical & Biological Engineering & Computing, Edición 63, 2025, Página(s) 467-482, ISSN 0140-0118
Editor: Institute of Electrical Engineers
DOI: 10.1007/s11517-024-03215-8

Modelling the anisotropic inelastic response of polymeric scaffolds for in situ tissue engineering applications (se abrirá en una nueva ventana)

Autores: Michele Terzano, Maximilian P. Wollner, Manuel P. Kainz, Malte Rolf-Pissarczyk, Nils Götzen and Gerhard A. Holzapfel
Publicado en: Journal of the royal society interface, 2023, ISSN 1742-5662
Editor: Royal Society
DOI: 10.1098/rsif.2023.0318

A reparameterization-invariant Bayesian framework for uncertainty estimation and calibration of simple materials (se abrirá en una nueva ventana)

Autores: Maximilian P. Wollner, Malte Rolf-Pissarczyk, Gerhard A. Holzapfel
Publicado en: Computational Mechanics, 2025, ISSN 0178-7675
Editor: Springer Verlag
DOI: 10.1007/s00466-024-02573-2

Re-interpretation of the Homogenized Constrained Mixture Theory within the plasticity framework and application to soft tissue growth and remodeling (se abrirá en una nueva ventana)

Autores: Felipe Sempértegui, Stéphane Avril
Publicado en: Computer Methods in Applied Mechanics and Engineering, Edición 412, 2023, Página(s) 116059, ISSN 0045-7825
Editor: Elsevier BV
DOI: 10.1016/j.cma.2023.116059

On the accuracy of the segmentation process and transcatheter heart valve dimensions in TAVI patients (se abrirá en una nueva ventana)

Autores: Roberta Scuoppo, Stefano Cannata, Caterina Gandolfo, Diego Bellavia, Salvatore Pasta
Publicado en: Journal of Biomechanics, Edición 176, 2024, Página(s) 112357, ISSN 0021-9290
Editor: Elsevier BV
DOI: 10.1016/j.jbiomech.2024.112357

A general model for anisotropic pseudo-elasticity and viscoelasticity at finite strains (se abrirá en una nueva ventana)

Autores: Maximilian P. Wollner a, Michele Terzano a, Malte Rolf-Pissarczyk a, Gerhard A. Holzapfel a b
Publicado en: Journal of the Mechanics and Physics of Solids, 2023, ISSN 0022-5096
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.jmps.2023.105403

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