Topological interactions as functional regulators of the eukaryotic genome: moving beyond intramolecular looping

Project Information

TopoGenomics

Grant agreement ID: 101019039

DOI

10.3030/101019039

EC signature date 13 August 2021

Start date 1 September 2021

End date 31 August 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 792 500,00

EU contribution

€ 2 792 500,00

Coordinated by

INSTITUT FUER MOLEKULARE BIOTECHNOLOGIE GMBH
Austria

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (5)

HiCognition: a visual exploration and hypothesis testing tool for 3D genomics

Author(s): Christoph C. H. Langer, Michael Mitter, Roman R. Stocsits, Daniel W. Gerlich
Published in: Genome Biology, 2023, ISSN 1474-7596
Publisher: BioMed Central
DOI: 10.1186/s13059-023-02996-9

Sister chromatid cohesion is mediated by individual cohesin complexes

Author(s): Fena Ochs, Charlotte Green, Aleksander Tomasz Szczurek, Lior Pytowski, Sofia Kolesnikova, Jill Brown, Daniel Wolfram Gerlich, Veronica Buckle, Lothar Schermelleh, Kim Ashley Nasmyth
Published in: Science, 2024, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.adl4606

Cohesin-mediated DNA loop extrusion resolves sister chromatids in G2 phase

Author(s): Paul Batty, Christoph C.H. Langer, Zsuzsanna Takács, Wen Tang, Claudia Blaukopf, Jan-Michael Peters, Daniel W. Gerlich
Published in: The EMBO Journal, 2023, ISSN 0261-4189
Publisher: Nature Publishing Group
DOI: 10.15252/embj.2023113475

Sister chromatid-sensitive Hi-C to map the conformation of replicated genomes

Author(s): Mitter M, Takacs Z, Köcher T, Micura R, Langer CCH, Gerlich DW.
Published in: Nature Protocols, Issue 2022 Jun;17(6), 2022, ISSN 1750-2799
Publisher: NPG
DOI: 10.1038/s41596-022-00687-6

Cohesin mediates DNA loop extrusion and sister chromatid cohesion by distinct mechanisms

Author(s): Kota Nagasaka, Iain F. Davidson, Roman R. Stocsits, Wen Tang, Gordana Wutz, Paul Betty, Melanie Panarotto, Gabriele Litos, Alexander Schleiffer, Daniel Wolfram Gerlich, Jan-Michael Peters
Published in: Molecular Cell, 2022, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2023.07.024