Tracing virus-specific CD8+ T cell clonotype zonation and function in humans

Informations projet

TRACE

N° de convention de subvention: 101041484

DOI

10.3030/101041484

Date de signature de la CE 18 Février 2022

Date de début 1 Juin 2022

Date de fin 31 Mai 2027

Financé au titre de

• European Research Council (ERC)

Coût total

€ 1 499 932,50

Contribution de l’UE

€ 1 499 932,00

Coordonné par

KAROLINSKA INSTITUTET
Sweden

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Data sets, microdata, etc (1)

Data Management Plan

A detailed data management plan DMP will be provided and periodically updated The DMP will ensure that all data and methods collected throughout the project follow the FAIR rules and define when data will be made available and shared with relevant stakeholders The DMP will provide a complete and extensive itemization of all technologies data to be collected including origin and means of creation format and associated metadata standards and the storage capacity needed to ensure conservation File formats will be chosen which are widely readable and common practice for the respective results The DMP will set the rules on how to report and store all data linked with TRACE to enable Open Access to data The PIs institution is the primary responsible of compliance to the DMP to ensure that access to repositories and sufficient capacity of data storage is provided for the project Data will be provided in standard digital readable formats eg xls rtf csv pdf Vocabulary documents will be provided with each data file

Publications

Peer reviewed articles (5)

Human circulating and tissue-resident memory CD8+ T cells

Auteurs: Buggert M, Price DA, Mackay LK, Betts MR
Publié dans: Nature Immunology, Numéro 24, 1076–1086, 2023, ISSN 1529-2916
Éditeur: Springer Nature
DOI: 10.1038/s41590-023-01538-6

Additive effects of booster mRNA vaccination and SARS-CoV-2 Omicron infection on T cell immunity across immunocompromised states

Auteurs: Müller TR, Sekine T, Trubach D, Niessl J, Chen P, Bergman P, Blennow O, Hansson L, Mielke S, Nowak P, Vesterbacka J, Akber M, Olofsson A, Amaya Hernandez SP, Gao Y, Cai C, Söderdahl G, Smith CIE, Österborg A, Loré K, Sällberg Chen M, Ljungman P, Ljunggre
Publié dans: Science Translational Medicine, Numéro Vol 15, Numéro 704, 2023, ISSN 1946-6234
Éditeur: American Association for the Advancement of Science
DOI: 10.1126/SCITRANSLMED.ADG9452

SARS-CoV-2 vaccination enhances the effector qualities of spike-specific T cells induced by COVID-19

Auteurs: Cai C, Gao Y, Adamo S, Rivera-Ballesteros O, Hansson L, Österborg A, Bergman P, Sandberg JK, Ljunggren HG, Björkström NK, Strålin K, Llewellyn-Lacey S, Price DA, Qin C, Grifoni A, Weiskopf D, Wherry EJ, Sette A, Aleman S, Buggert M
Publié dans: Science Immunology, Numéro Vol 8, Numéro 90, 2023, ISSN 2470-9468
Éditeur: American Association for the Advancement of Science
DOI: 10.1126/SCIIMMUNOL.ADH0687

Proceedings of the National Academy of Sciences of the United States of America

Auteurs: Humbert, Marion; Olofsson, Anna; Wullimann, David; Niessl, Julia; Hodcroft, Emma B; Cai, Curtis; Gao, Yu; Sohlberg, Ebba; Dyrdak, Robert; Mikaeloff, Flora; Neogi, Ujjwal; Albert, Jan; Malmberg, Karl-Johan; Lund-Johansen, Fridtjof; Aleman, Soo; Björkhem-Bergman, Linda; Jenmalm, Maria C; Ljunggren, Hans-Gustaf; Buggert, Marcus; Karlsson, Annika C
Publié dans: PNAS, 2023, ISSN 0027-8424
Éditeur: National Academy of Sciences (NAS)
DOI: 10.48350/180100

Memory profiles distinguish cross-reactive and virus-specific T cell immunity to mpox

Auteurs: Adamo S, Gao Y, Sekine T, Akhirunnesa M, Wu J, Storgärd E, Westergren V, Filén F, Treutiger CJ, Sandberg JK, Sällberg M, Bergman P, Llewellyn-Lacey S, Ljunggren HG, Price DA, Ekström AM, Sette A, Grifoni A, Buggert M
Publié dans: Cell Host & Microbe, 2023, ISSN 1934-6069
Éditeur: Cell Press
DOI: 10.1016/J.CHOM.2023.04.015