Tracing virus-specific CD8+ T cell clonotype zonation and function in humans

Información del proyecto

TRACE

Identificador del acuerdo de subvención: 101041484

DOI

10.3030/101041484

Fecha de la firma de la CE 18 Febrero 2022

Fecha de inicio 1 Junio 2022

Fecha de finalización 31 Mayo 2027

Financiado con arreglo a

• European Research Council (ERC)

Coste total

€ 1 499 932,50

Aportación de la UE

€ 1 499 932,00

Coordinado por

KAROLINSKA INSTITUTET
Sweden

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Data sets, microdata, etc (1)

Data Management Plan

A detailed data management plan DMP will be provided and periodically updated The DMP will ensure that all data and methods collected throughout the project follow the FAIR rules and define when data will be made available and shared with relevant stakeholders The DMP will provide a complete and extensive itemization of all technologies data to be collected including origin and means of creation format and associated metadata standards and the storage capacity needed to ensure conservation File formats will be chosen which are widely readable and common practice for the respective results The DMP will set the rules on how to report and store all data linked with TRACE to enable Open Access to data The PIs institution is the primary responsible of compliance to the DMP to ensure that access to repositories and sufficient capacity of data storage is provided for the project Data will be provided in standard digital readable formats eg xls rtf csv pdf Vocabulary documents will be provided with each data file

Publicaciones

Peer reviewed articles (5)

Human circulating and tissue-resident memory CD8+ T cells

Autores: Buggert M, Price DA, Mackay LK, Betts MR
Publicado en: Nature Immunology, Edición 24, 1076–1086, 2023, ISSN 1529-2916
Editor: Springer Nature
DOI: 10.1038/s41590-023-01538-6

Additive effects of booster mRNA vaccination and SARS-CoV-2 Omicron infection on T cell immunity across immunocompromised states

Autores: Müller TR, Sekine T, Trubach D, Niessl J, Chen P, Bergman P, Blennow O, Hansson L, Mielke S, Nowak P, Vesterbacka J, Akber M, Olofsson A, Amaya Hernandez SP, Gao Y, Cai C, Söderdahl G, Smith CIE, Österborg A, Loré K, Sällberg Chen M, Ljungman P, Ljunggre
Publicado en: Science Translational Medicine, Edición Vol 15, Edición 704, 2023, ISSN 1946-6234
Editor: American Association for the Advancement of Science
DOI: 10.1126/SCITRANSLMED.ADG9452

SARS-CoV-2 vaccination enhances the effector qualities of spike-specific T cells induced by COVID-19

Autores: Cai C, Gao Y, Adamo S, Rivera-Ballesteros O, Hansson L, Österborg A, Bergman P, Sandberg JK, Ljunggren HG, Björkström NK, Strålin K, Llewellyn-Lacey S, Price DA, Qin C, Grifoni A, Weiskopf D, Wherry EJ, Sette A, Aleman S, Buggert M
Publicado en: Science Immunology, Edición Vol 8, Edición 90, 2023, ISSN 2470-9468
Editor: American Association for the Advancement of Science
DOI: 10.1126/SCIIMMUNOL.ADH0687

Proceedings of the National Academy of Sciences of the United States of America

Autores: Humbert, Marion; Olofsson, Anna; Wullimann, David; Niessl, Julia; Hodcroft, Emma B; Cai, Curtis; Gao, Yu; Sohlberg, Ebba; Dyrdak, Robert; Mikaeloff, Flora; Neogi, Ujjwal; Albert, Jan; Malmberg, Karl-Johan; Lund-Johansen, Fridtjof; Aleman, Soo; Björkhem-Bergman, Linda; Jenmalm, Maria C; Ljunggren, Hans-Gustaf; Buggert, Marcus; Karlsson, Annika C
Publicado en: PNAS, 2023, ISSN 0027-8424
Editor: National Academy of Sciences (NAS)
DOI: 10.48350/180100

Memory profiles distinguish cross-reactive and virus-specific T cell immunity to mpox

Autores: Adamo S, Gao Y, Sekine T, Akhirunnesa M, Wu J, Storgärd E, Westergren V, Filén F, Treutiger CJ, Sandberg JK, Sällberg M, Bergman P, Llewellyn-Lacey S, Ljunggren HG, Price DA, Ekström AM, Sette A, Grifoni A, Buggert M
Publicado en: Cell Host & Microbe, 2023, ISSN 1934-6069
Editor: Cell Press
DOI: 10.1016/J.CHOM.2023.04.015