Project description
Rapid bacterial disease diagnostics for aquaculture
Outbreaks of bacterial diseases represent a persistent challenge to fish farming leading to significant economic loss. In nature, microorganisms exist in diverse communities. Consequently, a combination of species can cause infections. However, the co-species involvement in disease progression is poorly understood and represents a significant diagnostic challenge. The Marie Skłodowska-Curie Actions (MSCA) funded chelOMICS project proposes an ambitious multidisciplinary initiative to understand host-pathogen interactions in aquaculture fish as relates to vibriosis, photobacteriosis, and furunculosis, three major bacterial diseases. The project will apply modern multi-omics tools, metabolomics and metagenomics. chelOMICS will focus on the metabolome of siderophores, which are key virulence factors during infection, and their use as biomarkers for early disease diagnostics.
Objective
Outbreaks of bacterial diseases pose a persistent challenge to fish farming around the world causing significant economic loss. To improve efficiency, safety, and sustainability of aquaculture new health monitoring and rapid disease diagnostics approaches are required. Here, we propose an ambitious multidisciplinary project that implements modern multi-omics tools, in particular metabolomics and metagenomics, to provide a holistic understanding of host-pathogen interactions in farmed fish in the context of three major bacterial diseases; vibriosis, photobacteriosis, and furunculosis. This project will focus specifically on the metabolome of siderophores, iron chelating microbial metabolites that are key virulence factors during infection, and their use as biomarkers for early disease diagnostics. In nature, microorganisms exist in diverse communities and therefore infections can be caused by a combination of species yet the involvement of co-species in disease progression is poorly understood and represents a great diagnostic challenge. I have gained extensive skills in metabolomics through my PhD in Australia and postdoctoral experience in Germany. This project will enable me to go one step further; I will use different bioinformatic tools as well as imaging analytical chemistry (MALDI-IMS) approaches to integrate metabolomics and microbiome data and answer important ecological questions in aquaculture. I am highly motivated to take on this new challenge and acquire new scientific and transferable skills, which will strengthen my profile as an independent researcher and increase my opportunities for a permanent position after the fellowship.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- agricultural sciences agriculture, forestry, and fisheries fisheries
- natural sciences biological sciences microbiology
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2021-PF-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
15001 La Coruna
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.