Descrizione del progetto
Trattamento al plasma a bassa temperatura per la disinfezione di materiali polimerici
Le infezioni associate all’assistenza sanitaria e, in particolare, quelle correlate ai cateteri contribuiscono ad aumentare la mortalità e le ospedalizzazioni. Finanziato dal programma di azioni Marie Skłodowska-Curie, il progetto PlaTechMedi studierà l’applicazione delle tecnologie al plasma a bassa temperatura per la disinfezione dei materiali polimerici. L’obiettivo del progetto è la decontaminazione di batteri e biofilm dalla superficie del catetere e nei liquidi mediante trattamento al plasma. Il progetto studierà la risposta batterica alle specie reattive dell’ossigeno e dell’azoto in un liquido e l’inibizione della crescita del biofilm dopo il trattamento al plasma. Lo sviluppo della tecnologia al plasma per il trattamento dei polimeri e l’applicazione per il trattamento dei cateteri contribuirà a un’ampia gamma di nuove applicazioni industriali.
Obiettivo
Medical device-related infections contribute to an increase in mortality, prolongation of hospitalization and present a substantial financial burden to patients and society. Catheter-related infections are among the most common causes of healthcare-associated infections worldwide. The possibilities of low temperature plasma technologies for direct (plasma) and indirect (plasma activated water) disinfection of polymer materials will be studied.
The proposed project is focused on gaining detailed insight into the plasma processing of polymer medical tubes (catheters) using Surface Dielectric Barrier Discharge with liquid electrodes. This will include the investigation of plasma-induced physical and chemical changes not only on the surface of the processed material, but also the analysis of the surrounding gas, and especially the used liquid. Examination of the discharge under specific conditions is beneficial for the understanding of the undergoing chemical and physical processes. The decontamination effect of the plasma treatment of bacteria and biofilms present on the catheter surface and in liquids will be the key objective of the project. This will be done by detailed studies of the bacterial response to reactive oxygen and nitrogen species in liquid and the biofilm growth inhibition on the polymer after the plasma treatment.
The development of the plasma technology capable of polymer treatment in continuous regime and application of such plasma systems for catheters treatment will allow for a larger impact of plasma processing expanding to a wide range of new industrial applications. The obtained results will increase the quality of medical treatment, reduce the costs of specific medical care, and prolong the time between the required doctor visits for patients using different catheters.
Plasma applications in medicine are leaping to become the medicine of the future, and this is my chance to contribute to its development.
Campo scientifico
CORDIS classifica i progetti con EuroSciVoc, una tassonomia multilingue dei campi scientifici, attraverso un processo semi-automatico basato su tecniche NLP.
CORDIS classifica i progetti con EuroSciVoc, una tassonomia multilingue dei campi scientifici, attraverso un processo semi-automatico basato su tecniche NLP.
Parole chiave
Programma(i)
- HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA) Main Programme
Meccanismo di finanziamento
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European FellowshipsCoordinatore
814 99 Bratislava
Slovacchia