A Modular Framework for Designing and Producing Biohybrid Machines

Project Information

BioMeld

Grant agreement ID: 101070328

DOI

10.3030/101070328

EC signature date 24 June 2022

Start date 1 October 2022

End date 31 March 2026

Funded under

• Digital, Industry and Space

Total cost

€ 3 978 056,93

EU contribution

€ 3 978 056,93

Coordinated by

UNIVERZITET U NOVOM SADU, POLJOPRIVREDNI FAKULTET NOVI SAD
Serbia

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (19)

Plan for Dissemination, Exploitation and Communication

Plan will be periodically updated and presented at periodic review meetings.

Performance simulations and analysis of results

Report on performed simulations, their correlation with experiments and analysis of predictive power. Updated at month 36.

Data management plan

Data management plan done in accordance to EC template

The Framework specifications

Periodic reports on the initial framework specifications (M06) and further developments, standards implemented, how it is integrated with the BIMC development. Deliverable updates will be done at Months 18 and 36

Experimental performance

Report on performed tests and obtained results. Updated at month 36

Catheter muscle integration

Report on integrating muscle contraction-based motion into a catheter, the production methods chosen and parameters used for that choice.

Report of the kick-off meeting

Report of the decisions from the kick-off meeting.

Additional simulation modules

Report on developed modules for simulating electric stimulus-response and rotation&bending dynamics, how they are implemented, and performance results.

Early career development

Periodic reports on performed activities described in T5.2. Updated at Month 36.

IP, regulation and dissemination report

Periodic reports on performed activities in T5.5-6. Updated at month 36.

System observables

Report on the estimated main observable parameters for modelling biohybrid catheter.

Culture and actuator chamber with integrated sensors

Progress report (M18) and the final report (M28) on the chamber design and fabrication.

Test plan & cases

Report on developed documentation templates, test plan, test cases and updates (on months 18 and 30).

Uncertainty analysis

Reports on uncertainty & sensitivity analyses, and acceptability ranges. Updated at month 36.

3D evolvable simulator

Report on the implemented voxel-based simulator, how it is integrated with evolvable algorithms and performance results.

Machine learning optimization

Report on DNN methodology applied, tests performed, parameter and metaparameter optimizations, performances. The updated version will be uploaded in month 36.

Feedback system control software

Progress report (M18) and the final report (M32) on the control software development, testing and calibration results.

Bill of materials

Report on the first version (M06) and the final, updated BOM will be updated at M24

BHM Catheter skeleton design and fabrication

Report on catheter design, structure, materials used, test results.

Websites, patent fillings, videos etc. (1)

Web and public presence

Launched website, social media, flyers

Publications

Conference proceedings (3)

A novel concept of steerable catheters actuated by muscle cells: the BioMeld project

Author(s): Salvatori C, Ricotti L, Vannozzi L
Published in: 2023, ISSN 2724-2129
Publisher: Gruppo Nazionale di Bioingegneria

Incremental Growth on Compositional Pattern Producing Networks Based Optimization of Biohybrid Actuators

Author(s): Tsompanas, MA
Published in: 2024, ISSN 1611-3349
Publisher: Springer Nature Switzerland AG
DOI: 10.1007/978-3-031-56855-8_17

A Novel Steerable Catheter Controlled with a Biohybrid Actuator: A Feasibility Study

Author(s): Salvatori, C., Trucco, D., Niosi, I., Ricotti, L., Vannozzi, L.
Published in: 2023, ISSN 1611-3349
Publisher: Springer, Cham
DOI: 10.1007/978-3-031-39504-8_26

Peer reviewed articles (2)

Merging BioActuation and BioCapacitive properties: A 3D bioprinted devices to self-stimulate using self-stored energy

Author(s): Brenda G. Molina, Judith Fuentes, Carlos Alemán, Samuel Sánchez
Published in: Biosensors and Bioelectronics, Issue Volume 251, 1 May 2024, 116117, 2024, ISSN 0956-5663
Publisher: Elsevier
DOI: 10.1016/j.bios.2024.116117

Outline of an evolutionary morphology generator towards the modular design of a biohybrid catheter

Author(s): Michail-Antisthenis Tsompanas, Igor Balaz
Published in: Frontiers in Robotics and AI, 2024, ISSN 2296-9144
Publisher: Frontiers Media SA
DOI: 10.3389/frobt.2024.1337722