Discovering Collagen I degradation process in chronic diseases with fibrotic component

Informazioni relative al progetto

DisCo-I

ID dell’accordo di sovvenzione: 101072828

DOI

10.3030/101072828

Data della firma CE 7 Giugno 2022

Data di avvio 1 Settembre 2022

Data di completamento 31 Agosto 2026

Finanziato da

• Marie Skłodowska-Curie Actions (MSCA)

Costo totale

Nessun dato

Contributo UE

€ 1 648 915,20

Coordinato da

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Websites, patent fillings, videos etc. (1)

Launch of the project website and social media accounts

Pubblicazioni

Peer reviewed articles (14)

Assessment and Risk Prediction of Chronic Kidney Disease and Kidney Fibrosis Using Non-Invasive Biomarkers

Autori: Harald Rupprecht, Lorenzo Catanese, Kerstin Amann, Felicitas E. Hengel, Tobias B. Huber, Agnieszka Latosinska, Maja T. Lindenmeyer, Harald Mischak, Justyna Siwy, Ralph Wendt, Joachim Beige
Pubblicato in: International Journal of Molecular Sciences, Numero 25, 2024, ISSN 1422-0067
Editore: MDPI AG
DOI: 10.3390/ijms25073678

Urinary peptides provide information about the risk of mortality across a spectrum of diseases and scenarios

Autori: Keller F, Beige J, Siwy J, Mebazaa A, An D, Mischak H, Schanstra JP, Mokou M, Perco P, Staessen JA, Vlahou A, Latosinska A
Pubblicato in: Journal of Translational Medicine, 2023, ISSN 1479-5876
Editore: BioMed Central
DOI: 10.1186/s12967-023-04508-6

Gut alterations in a chronic kidney disease rat model with diet‐induced vascular calcification

Autori: Piotr Bartochowski, Irene Cortijo, Shruti Bhargava, Bernard Jover, Fabrice Raynaud, Juliana H Boukhaled, Anne‐Dominique Lajoix, Vera Jankowski, Joachim Jankowski, Magali Cordaillat‐Simmons, Àngel Argilés, Nathalie Gayrard, Flore Duranton, Jonas Laget
Pubblicato in: FEBS Open Bio, Numero 15, 2025, ISSN 2211-5463
Editore: Wiley
DOI: 10.1002/2211-5463.70043

Association of Urinary Collagen Type III Degradation Product With Kidney Function and Fibrosis in Chronic Kidney Disease Patients

Autori: Emily M. Martin, Federica Genovese, Harald Mischak, Justyna Siwy, Harald Rupprecht, Lorenzo Catanese, Agnieszka Latosinska
Pubblicato in: PROTEOMICS, 2025, ISSN 1615-9853
Editore: Wiley
DOI: 10.1002/PMIC.202400354

Clinical Proteomics, Quo Vadis?

Autori: Harald Mischak, Joost P. Schanstra, Antonia Vlahou, Joachim Beige
Pubblicato in: PROTEOMICS, Numero 25, 2025, ISSN 1615-9853
Editore: Wiley
DOI: 10.1002/PMIC.202400346

Circulating collagen type I fragments as specific biomarkers of cardiovascular outcome risk: Where are the opportunities?

Autori: Emily M. Martin, Joan Chang, Arantxa González, Federica Genovese
Pubblicato in: Matrix Biology, Numero 137, 2025, ISSN 0945-053X
Editore: Elsevier BV
DOI: 10.1016/J.MATBIO.2025.03.001

Prognosis and Personalized In Silico Prediction of Treatment Efficacy in Cardiovascular and Chronic Kidney Disease: A Proof-of-Concept Study

Autori: Jaimes Campos MA, Andújar I, Keller F, Mayer G, Rossing P, Staessen JA, Delles C, Beige J, Glorieux G, Clark AL, Mullen W, Schanstra JP, Vlahou A, Rossing K, Peter K, Ortiz A, Campbell A, Persson F, Latosinska A, Mischak H, Siwy J, Jankowski J
Pubblicato in: Pharmaceuticals (Basel), 2023, ISSN 1424-8247
Editore: MDPI
DOI: 10.3390/PH16091298

Multiple urinary peptides display distinct sex-specific distribution

Autori: Mina IK, Mavrogeorgis E, Siwy J, Stojanov R, Mischak H, Latosinska A, Jankowski V
Pubblicato in: Proteomics, 2013, ISSN 1615-9861
Editore: Wiley VCH
DOI: 10.1002/pmic.202300227

Reviewing the Regulators of COL1A1

Autori: Devos H, Zoidakis J, Roubelakis MG, Latosinska A, Vlahou A
Pubblicato in: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Editore: MDPI
DOI: 10.3390/ijms241210004

Cafeteria Diet-Induced Obesity Worsens Experimental CKD

Autori: Laget J, Cortijo I, Boukhaled JH, Muyor K, Duranton F, Jover B, Raynaud F, Lajoix AD, Argilés À, Gayrard N
Pubblicato in: Nutrients, 2023, ISSN 2072-6643
Editore: MDPI
DOI: 10.3390/nu15153331

The Omics‐Driven Machine Learning Path to Cost‐Effective Precision Medicine in Chronic Kidney Disease

Autori: Marta B. Lopes, Roberta Coletti, Flore Duranton, Griet Glorieux, Mayra Alejandra Jaimes Campos, Julie Klein, Matthias Ley, Paul Perco, Alexia Sampri, Aviad Tur‐Sinai
Pubblicato in: PROTEOMICS, 2025, ISSN 1615-9853
Editore: Wiley
DOI: 10.1002/pmic.202400108

Urinary peptide analysis to predict the response to blood pressure medication

Autori: Jaimes Campos MA, Mavrogeorgis E, Latosinska A, Eder S, Buchwinkler L, Mischak H, Siwy J, Rossing P, Mayer G, Jankowski J
Pubblicato in: Nephrology Dialysis Transplantation, 2023, ISSN 1460-2385
Editore: Oxford University Press
DOI: 10.1093/ndt/gfad223

A Naturally Occurring Urinary Collagen Type I Alpha 1-Derived Peptide Inhibits Collagen Type I-Induced Endothelial Cell Migration at Physiological Concentrations

Autori: Hanne Devos, Ioanna K. Mina, Foteini Paradeisi, Manousos Makridakis, Aggeliki Tserga, Marika Mokou, Jerome Zoidakis, Harald Mischak, Antonia Vlahou, Agnieszka Latosinska, Maria G. Roubelakis
Pubblicato in: International Journal of Molecular Sciences, Numero 26, 2025, ISSN 1422-0067
Editore: MDPI AG
DOI: 10.3390/IJMS26157480

Investigation of the Urinary Peptidome to Unravel Collagen Degradation in Health and Kidney Disease

Autori: Ioanna K. Mina, Luis F. Iglesias‐Martinez, Matthias Ley, Lucas Fillinger, Paul Perco, Justyna Siwy, Harald Mischak, Vera Jankowski
Pubblicato in: PROTEOMICS, 2024, ISSN 1615-9853
Editore: Wiley
DOI: 10.1002/pmic.202400279

Other (1)

A synthetic data generation pipeline to reproducibly mirror high-resolution multi-variable peptidomics and real-patient clinical data

Autori: Mayra Alejandra Jaimes Campos, Stipe Kabić, Agnieszka Latosinska, Ena Anicic, Justyna Siwy, Vinko Dragušica, Harald Rupprecht, Lorenzo Catanese, Felix Keller, Paul Perco, Enrique Gomez- Gomez, Joachim Beige, Antonia Vlahou, Harald Mischak, Davorin Vukelić, Tomislav Križan, Maria Frantzi
Pubblicato in: 2024
Editore: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.10.30.24316342