Descrizione del progetto
Una rete di formazione per applicazioni di imaging 3D basato sul tempo di vita della fluorescenza nel campo della medicina
Il progetto flIMAGIN3D, finanziato dal programma di azioni Marie Skłodowska-Curie, creerà une rete di formazione per la ricerca su applicazioni biomediche di microscopia di imaging 3D basato sul tempo di vita della fluorescenza (FLIM, fluorescent lifetime imaging microscopy). Il progetto si propone di reclutare 10 dottorandi per la creazione di piattaforme solide, intuitive, innovative e basate sulla FLIM destinate a una vasta gamma di applicazioni biomediche. La rete di formazione coprirà la base teorica fondamentale della FLIM e, mediante lo svolgimento di progetti specifici, punterà a colmare l’attuale lacuna di conoscenze presente nelle applicazioni fotoniche nel settore della biologia. I ricercatori nella fase iniziale della propria carriera coinvolti in flIMAGIN3D svilupperanno piattaforme FLIM in grado di fornire nuove informazioni allo scopo di comprendere la biologia in condizioni di malattia, differenziazione, sviluppo e interventi con una risoluzione elevata.
Obiettivo
In flIMAGIN3D, which centres on fluorescent lifetime imaging microscopy applied to biomedical platforms in 3D; ten talented Doctoral Candidates (DCs) will be recruited, trained and supervised to cohesively establish the most robust, user accessible and powerful FLIM-based platform-never achieved before, and apply it to a wide range of applications in the biological sciences.
flIMAGIN3D will generate ten DCs at the cutting edge of FLIM-based biological imaging who will spearhead, and go onto catalyse clusters of FLIM excellence across Europe; each intertwined within a collaborative network that will extend beyond the time-frame of the program. This doctoral network will train talented doctoral candidates in the essential theories underpinning FLIM , and through the individual projects and extensive secondments in this network; elevate their projects and skills, and that of their secondment hosts to research excellence in FLIM flIMAGIN3D addresses a significant knowledge gap in the field of photonics in biology by involving biomedical scientists in each and every aspect of development and design, and cognisant of the wide variety of current platforms that require adaptability to such modalities.
In flIMAGIN3D: bringing together representatives with different applications and backgrounds, we will identify and overcome barriers to FLIM imaging by developing the next generation of scientists who will develop a FLIM platform capable of extracting the greatest amount of information possible in a stream-lined, accurate and user-friendly manner in order to understand biology in disease, differentiation, development and interventions at a high resolution. To achieve this goal, the trained scientists will develop cheaper advanced hardware components, with user friendly software that can build precise libraries for accurate machine learning classifications and plug-and-play platforms and sensors to facilitate a wide range of applications.
Campo scientifico
- natural sciencescomputer and information sciencessoftware
- natural sciencesbiological sciences
- natural sciencesphysical sciencesopticsmicroscopy
- engineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensors
- natural sciencescomputer and information sciencesartificial intelligencemachine learning
Parole chiave
Programma(i)
- HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA) Main Programme
Meccanismo di finanziamento
HORIZON-TMA-MSCA-DN - HORIZON TMA MSCA Doctoral NetworksCoordinatore
D02 CX56 Dublin
Irlanda