Doctoral Network for a Shared Excellence of Fluorescent Lifetime Imaging Microscopy in Biomedical Applications

Informazioni relative al progetto

flIMAGIN3D

ID dell’accordo di sovvenzione: 101073507

DOI

10.3030/101073507

Data della firma CE 15 Luglio 2022

Data di avvio 1 Gennaio 2023

Data di completamento 31 Dicembre 2026

Finanziato da

• Marie Skłodowska-Curie Actions (MSCA)

Costo totale

Nessun dato

Contributo UE

€ 2 743 459,20

Coordinato da

THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
Ireland

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Websites, patent fillings, videos etc. (3)

Publication of recruitment call

Call for DC applications announced via all supervisor channels, EURAXXAS portal

Updated flIMAGIN3D website/ social media accounts are live

Virtual portal is live for partners, and public website of the consortium

Link(s) to EURAXESS advertisement(s) of the positions

Documents, reports (1)

Secondment Plan

Secondment Plan (M12)

Other (1)

Banners, flyers and posters are available

All partners have acesss to all media files, logos, posters and promotional and dissemination level templates related to flIMAGIN3D.

Pubblicazioni

Peer reviewed articles (21)

Production and Multi-Parameter Live Cell Fluorescence Lifetime Imaging Microscopy (FLIM) of Multicellular Spheroids

Autori: Angela C. Debruyne, Gabriele Ferrari, Hang Zhou, Nore Van Loon, Nina Heymans, Irina A. Okkelman, Ruslan I. Dmitriev
Pubblicato in: Journal of Visualized Experiments, 2024, ISSN 1940-087X
Editore: MyJove Corporation
DOI: 10.3791/66845

2P-FLIM unveils time-dependent metabolic shifts during osteogenic differentiation with a key role of lactate to fuel osteogenesis via glutaminolysis identified

Autori: Nuno G. B. Neto, Meenakshi Suku, David A. Hoey & Michael G. Monaghan
Pubblicato in: Stem Cell Research & Therapy, Numero 364, 2023
Editore: BMC
DOI: 10.1186/s13287-023-03606-y

Description of Pseudomonas imrae sp. nov., carrying a novel class C β-lactamase gene variant, isolated from gut samples of Atlantic mackerel (Scomber scombrus)

Autori: Francisco Salvà-Serra; Francisco Salvà-Serra; Francisco Salvà-Serra; Francisco Salvà-Serra; Francisco Salvà-Serra; Priyank Nimje; Beatriz Piñeiro-Iglesias; Beatriz Piñeiro-Iglesias; Leonarda Achá Alarcón; Leonarda Achá Alarcón; Leonarda Achá Alarcón; Sofia Cardew; Sofia Cardew; Elisabeth Inganäs; Elisabeth Inganäs; Susanne Jensie-Markopoulos; Susanne Jensie-Markopoulos; Maria Ohlén; Maria Ohlén; Hanna-Sophia Sailer; Hanna-Sophia Sailer; Christel Unosson; Christel Unosson; Víctor Fernández-Juárez; Cesar O. Pacherres; Michael Kühl; Edward R. B. Moore; Edward R. B. Moore; Edward R. B. Moore; Edward R. B. Moore; Nachiket P. Marathe
Pubblicato in: Frontiers in Microbiology, 2025
Editore: FRONTIERS
DOI: 10.3389/FMICB.2025.1530878

Engineering macrophage responses through 3D scaffold microarchitecture

Autori: Chiara Martinelli, Srijan Chakraborty, Giovanni Buccioli, Matteo Vicini, Claudio Conci, Giulio Cerullo, Roberto Osellame, Giuseppe Chirico, Emanuela Jacchetti, Manuela Teresa Raimondi
Pubblicato in: Materials Today Bio, Numero 35, 2025, ISSN 2590-0064
Editore: Elsevier BV
DOI: 10.1016/J.MTBIO.2025.102328

In-vivo Lifetime Imaging of the Internal O2 Dynamics in Corals with NIR-emitting Sensor Nanoparticles

Autori: Michael Kühl; Daniel Aagren Nielsen; Sergey M. Borisov
Pubblicato in: Crossref, 2024
Editore: CHERMXIV
DOI: 10.26434/CHEMRXIV-2024-M6KJ8

Oxygen Supply of Islets of Langerhans by Photosynthetically Active Microalgae in Bioprinted Co‐Cultures Maintains Their Function in a Hypoxic Environment

Autori: Finn Dani, Sarah Duin, Ashwini Rahul Akkineni, Susann Lehmann, Barbara Ludwig, Michael Kühl, Michael Gelinsky, Anja Lode
Pubblicato in: Advanced Healthcare Materials, 2026, ISSN 2192-2640
Editore: Wiley
DOI: 10.1002/ADHM.202505927

Functional imaging of 3D bioprinted microalgal constructs and simulation of their photosynthetic performance

Autori: Swathi Murthy, Maria Mosshammer, Erik Trampe, Michael Kühl
Pubblicato in: Biofabrication, Numero 17, 2025, ISSN 1758-5082
Editore: IOP Publishing
DOI: 10.1088/1758-5090/ADF9CA

Visualizing the internalization and biological impact of nanoplastics in live intestinal organoids by Fluorescence Lifetime Imaging Microscopy (FLIM)

Autori: Irina A. Okkelman, Hang Zhou, Sergey M. Borisov, Angela C. Debruyne, Austin E. Y. T. Lefebvre, Marcelo Leomil Zoccoler, Linglong Chen, Bert Devriendt, Ruslan I. Dmitriev
Pubblicato in: Light: Science & Applications, Numero 14, 2025, ISSN 2047-7538
Editore: Springer Science and Business Media LLC
DOI: 10.1038/S41377-025-01949-0

Cytosolic‐enhanced dark Epac‐based <scp>FRET</scp> sensors allow for intracellular <scp>cAMP</scp> detection in live cells via <scp>FLIM</scp>

Autori: Giulia Zanetti, Jeffrey B. Klarenbeek, Kees Jalink
Pubblicato in: FEBS Letters, 2024, ISSN 0014-5793
Editore: Wiley
DOI: 10.1002/1873-3468.15093

Advanced healthcare materials

Autori: Finn Dani, Sarah Duin, Ashwini Rahul Akkineni, Susann Lehmann, Barbara Ludwig, Michael Kühl, Michael Gelinsky, Anja Lode
Pubblicato in: Advanced Healthcare Materials, ISSN 2192-2640
Editore: Advanced Healthcare Materials
DOI: 10.1002/ADHM.202505927DIGITALOBJECTIDENTIFIER(DOI)

Novel Approach for Lifetime-Proportional Luminescence Imaging Using Frame Straddling

Autori: Soeren Ahmerkamp, Cesar O. Pacherres, Maria Mosshammer, Mathilde Godefroid, Michael Wind-Hansen, Marcel Kuypers, Lars Behrendt, Klaus Koren, Michael Kühl
Pubblicato in: ACS Sensors, Numero 9, 2024, ISSN 2379-3694
Editore: American Chemical Society (ACS)
DOI: 10.1021/ACSSENSORS.4C01828

Luminescence Lifetime Imaging: Key Concepts and Advances in the Image Acquisition, Processing, and Analysis Pipeline

Autori: Rishi Harkhoe, Gabriele Ferrari, Ruslan I. Dmitriev, Michael Kühl
Pubblicato in: ACS Measurement Science Au, 2026, ISSN 2694-250X
Editore: American Chemical Society (ACS)
DOI: 10.1021/ACSMEASURESCIAU.5C00209

Thou shall not heal: Overcoming the non-healing behaviour of diabetic foot ulcers by engineering the inflammatory microenvironment

Autori: Michael G. Monaghan, Rajiv Borah, Charlotte Thomsen, Shane Browne,
Pubblicato in: Advanced Drug Delivery Reviews, Numero 203, 2023, ISSN 0169-409X
Editore: Elvesier
DOI: 10.1016/j.addr.2023.115120

<i>In Vivo</i> Lifetime Imaging of the Internal O₂ Dynamics in Corals with near-Infrared-Emitting Sensor Nanoparticles

Autori: Michael Kühl, Daniel Aagren Nielsen, Sergey M. Borisov
Pubblicato in: ACS Sensors, Numero 9, 2024, ISSN 2379-3694
Editore: American Chemical Society (ACS)
DOI: 10.1021/ACSSENSORS.4C01029

Live Microscopy of Multicellular Spheroids with the Multimodal Near-Infrared Nanoparticles Reveals Differences in Oxygenation Gradients

Autori: Angela C. Debruyne, Irina A. Okkelman, Nina Heymans, Cláudio Pinheiro, An Hendrix, Max Nobis, Sergey M. Borisov, Ruslan I. Dmitriev
Pubblicato in: ACS Nano, Numero 18, 2024, ISSN 1936-0851
Editore: American Chemical Society (ACS)
DOI: 10.1021/ACSNANO.3C12539

Parallelizing Adaptive Reliability Analysis Through Penalizing the Learning Function

Autori: Guangchen Wang; Michael Monaghan; Mimi Zhang
Pubblicato in: IEEE Transactions on Reliability, 2024
Editore: IEEE
DOI: 10.1109/TR.2024.3483307

Engineering macrophage responses through 3D scaffold microarchitecture

Autori: Chiara Martinelli; Srijan Chakraborty; Giovanni Buccioli; Matteo Vicini; Claudio Conci; Giulio Cerullo; Roberto Osellame; Giuseppe Chirico; Emanuela Jacchetti; Manuela Teresa Raimondi
Pubblicato in: Materials Today Bio, 2025
Editore: ELSEVIER
DOI: 10.1016/J.MTBIO.2025.102328

3D photopolymerized microstructured scaffolds influence nuclear deformation, nucleo/cytoskeletal protein organization, and gene regulation in mesenchymal stem cells

Autori: Francesca Donnaloja; Manuela Teresa Raimondi; Letizia Messa; Bianca Barzaghini; Federica Carnevali; Emanuele Colombo; Davide Mazza; Chiara Martinelli; Lucia Boeri; Federica Rey; Cristina Cereda; Roberto Osellame; Giulio Cerullo; Stephana Carelli; Monica Soncini; Emanuela Jacchetti
Pubblicato in: APL Bioengineering, 2023
Editore: AIP PUBLISHING
DOI: 10.1063/5.0153215

Probing organoid metabolism using fluorescence lifetime imaging microscopy (FLIM): The next frontier of drug discovery and disease understanding

Autori: Margarida Barroso, Michael G. Monaghan, Raluca Niesner, Ruslan I. Dmitriev,
Pubblicato in: Advanced Drug Delivery Reviews, Numero 201, 2023, ISSN 0169-409X
Editore: Elvesier
DOI: 10.1016/j.addr.2023.115081

Lack of biochemical signalling in GelMA leads to polarity reversion in intestinal organoids independent from mechanoreciprocity

Autori: Lenie Vanhove; Thomas Van Gansbeke; Bert Devriendt; Ruben Van der Meeren; Ruslan I. Dmitriev; Irina A. Okkelman
Pubblicato in: Journal of Tissue Engineering, 2025
Editore: SAGE JOURNALS
DOI: 10.1177/20417314251345000

A scanning particle image velocimetry system for spatial mapping of steady flow and <scp>O₂</scp> concentration fields around aquatic organisms

Autori: Cesar O. Pacherres; Amin A. Huber; Swathi Murthy; Michael Kühl
Pubblicato in: Methods in Ecology and Evolution, 2025
Editore: BRITISH ECOLOGICAL SOCIETY
DOI: 10.1111/2041-210X.70073

Other (2)

Biochemical resolving power of fluorescence lifetime imaging: untangling the roles of the instrument response function and photon-statistics

Autori: Esposito, Alessandro
Pubblicato in: 2023
DOI: 10.5281/zenodo.7796539

ECM Proteins Nidogen‐1 and Decorin Restore Functionality of Human Islets of Langerhans upon Hypoxic Conditions

Autori: Abiramy Jeyagaran; Max Urbanczyk; Daniel Carvajal‐Berrio; Teresa Baldissera; Philipp D. Kaiser; Laurence Kuhlburger; Stefan Czemmel; Sven Nahnsen; Garry P. Duffy; Sara Y. Brucker; Shannon L. Layland; Katja Schenke‐Layland
Pubblicato in: Advanced Healthcare Materials, 2024
DOI: 10.1002/ADHM.202403017