Doctoral Network for a Shared Excellence of Fluorescent Lifetime Imaging Microscopy in Biomedical Applications

Información del proyecto

flIMAGIN3D

Identificador del acuerdo de subvención: 101073507

DOI

10.3030/101073507

Fecha de la firma de la CE 15 Julio 2022

Fecha de inicio 1 Enero 2023

Fecha de finalización 31 Diciembre 2026

Financiado con arreglo a

• Marie Skłodowska-Curie Actions (MSCA)

Coste total

Sin datos

Aportación de la UE

€ 2 743 459,20

Coordinado por

THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
Ireland

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Websites, patent fillings, videos etc. (3)

Publication of recruitment call

Call for DC applications announced via all supervisor channels, EURAXXAS portal

Updated flIMAGIN3D website/ social media accounts are live

Virtual portal is live for partners, and public website of the consortium

Link(s) to EURAXESS advertisement(s) of the positions

Documents, reports (1)

Secondment Plan

Secondment Plan (M12)

Other (1)

Banners, flyers and posters are available

All partners have acesss to all media files, logos, posters and promotional and dissemination level templates related to flIMAGIN3D.

Publicaciones

Peer reviewed articles (21)

Production and Multi-Parameter Live Cell Fluorescence Lifetime Imaging Microscopy (FLIM) of Multicellular Spheroids

Autores: Angela C. Debruyne, Gabriele Ferrari, Hang Zhou, Nore Van Loon, Nina Heymans, Irina A. Okkelman, Ruslan I. Dmitriev
Publicado en: Journal of Visualized Experiments, 2024, ISSN 1940-087X
Editor: MyJove Corporation
DOI: 10.3791/66845

2P-FLIM unveils time-dependent metabolic shifts during osteogenic differentiation with a key role of lactate to fuel osteogenesis via glutaminolysis identified

Autores: Nuno G. B. Neto, Meenakshi Suku, David A. Hoey & Michael G. Monaghan
Publicado en: Stem Cell Research & Therapy, Edición 364, 2023
Editor: BMC
DOI: 10.1186/s13287-023-03606-y

Description of Pseudomonas imrae sp. nov., carrying a novel class C β-lactamase gene variant, isolated from gut samples of Atlantic mackerel (Scomber scombrus)

Autores: Francisco Salvà-Serra; Francisco Salvà-Serra; Francisco Salvà-Serra; Francisco Salvà-Serra; Francisco Salvà-Serra; Priyank Nimje; Beatriz Piñeiro-Iglesias; Beatriz Piñeiro-Iglesias; Leonarda Achá Alarcón; Leonarda Achá Alarcón; Leonarda Achá Alarcón; Sofia Cardew; Sofia Cardew; Elisabeth Inganäs; Elisabeth Inganäs; Susanne Jensie-Markopoulos; Susanne Jensie-Markopoulos; Maria Ohlén; Maria Ohlén; Hanna-Sophia Sailer; Hanna-Sophia Sailer; Christel Unosson; Christel Unosson; Víctor Fernández-Juárez; Cesar O. Pacherres; Michael Kühl; Edward R. B. Moore; Edward R. B. Moore; Edward R. B. Moore; Edward R. B. Moore; Nachiket P. Marathe
Publicado en: Frontiers in Microbiology, 2025
Editor: FRONTIERS
DOI: 10.3389/FMICB.2025.1530878

Engineering macrophage responses through 3D scaffold microarchitecture

Autores: Chiara Martinelli, Srijan Chakraborty, Giovanni Buccioli, Matteo Vicini, Claudio Conci, Giulio Cerullo, Roberto Osellame, Giuseppe Chirico, Emanuela Jacchetti, Manuela Teresa Raimondi
Publicado en: Materials Today Bio, Edición 35, 2025, ISSN 2590-0064
Editor: Elsevier BV
DOI: 10.1016/J.MTBIO.2025.102328

In-vivo Lifetime Imaging of the Internal O2 Dynamics in Corals with NIR-emitting Sensor Nanoparticles

Autores: Michael Kühl; Daniel Aagren Nielsen; Sergey M. Borisov
Publicado en: Crossref, 2024
Editor: CHERMXIV
DOI: 10.26434/CHEMRXIV-2024-M6KJ8

Oxygen Supply of Islets of Langerhans by Photosynthetically Active Microalgae in Bioprinted Co‐Cultures Maintains Their Function in a Hypoxic Environment

Autores: Finn Dani, Sarah Duin, Ashwini Rahul Akkineni, Susann Lehmann, Barbara Ludwig, Michael Kühl, Michael Gelinsky, Anja Lode
Publicado en: Advanced Healthcare Materials, 2026, ISSN 2192-2640
Editor: Wiley
DOI: 10.1002/ADHM.202505927

Functional imaging of 3D bioprinted microalgal constructs and simulation of their photosynthetic performance

Autores: Swathi Murthy, Maria Mosshammer, Erik Trampe, Michael Kühl
Publicado en: Biofabrication, Edición 17, 2025, ISSN 1758-5082
Editor: IOP Publishing
DOI: 10.1088/1758-5090/ADF9CA

Visualizing the internalization and biological impact of nanoplastics in live intestinal organoids by Fluorescence Lifetime Imaging Microscopy (FLIM)

Autores: Irina A. Okkelman, Hang Zhou, Sergey M. Borisov, Angela C. Debruyne, Austin E. Y. T. Lefebvre, Marcelo Leomil Zoccoler, Linglong Chen, Bert Devriendt, Ruslan I. Dmitriev
Publicado en: Light: Science & Applications, Edición 14, 2025, ISSN 2047-7538
Editor: Springer Science and Business Media LLC
DOI: 10.1038/S41377-025-01949-0

Cytosolic‐enhanced dark Epac‐based <scp>FRET</scp> sensors allow for intracellular <scp>cAMP</scp> detection in live cells via <scp>FLIM</scp>

Autores: Giulia Zanetti, Jeffrey B. Klarenbeek, Kees Jalink
Publicado en: FEBS Letters, 2024, ISSN 0014-5793
Editor: Wiley
DOI: 10.1002/1873-3468.15093

Advanced healthcare materials

Autores: Finn Dani, Sarah Duin, Ashwini Rahul Akkineni, Susann Lehmann, Barbara Ludwig, Michael Kühl, Michael Gelinsky, Anja Lode
Publicado en: Advanced Healthcare Materials, ISSN 2192-2640
Editor: Advanced Healthcare Materials
DOI: 10.1002/ADHM.202505927DIGITALOBJECTIDENTIFIER(DOI)

Novel Approach for Lifetime-Proportional Luminescence Imaging Using Frame Straddling

Autores: Soeren Ahmerkamp, Cesar O. Pacherres, Maria Mosshammer, Mathilde Godefroid, Michael Wind-Hansen, Marcel Kuypers, Lars Behrendt, Klaus Koren, Michael Kühl
Publicado en: ACS Sensors, Edición 9, 2024, ISSN 2379-3694
Editor: American Chemical Society (ACS)
DOI: 10.1021/ACSSENSORS.4C01828

Luminescence Lifetime Imaging: Key Concepts and Advances in the Image Acquisition, Processing, and Analysis Pipeline

Autores: Rishi Harkhoe, Gabriele Ferrari, Ruslan I. Dmitriev, Michael Kühl
Publicado en: ACS Measurement Science Au, 2026, ISSN 2694-250X
Editor: American Chemical Society (ACS)
DOI: 10.1021/ACSMEASURESCIAU.5C00209

Thou shall not heal: Overcoming the non-healing behaviour of diabetic foot ulcers by engineering the inflammatory microenvironment

Autores: Michael G. Monaghan, Rajiv Borah, Charlotte Thomsen, Shane Browne,
Publicado en: Advanced Drug Delivery Reviews, Edición 203, 2023, ISSN 0169-409X
Editor: Elvesier
DOI: 10.1016/j.addr.2023.115120

<i>In Vivo</i> Lifetime Imaging of the Internal O₂ Dynamics in Corals with near-Infrared-Emitting Sensor Nanoparticles

Autores: Michael Kühl, Daniel Aagren Nielsen, Sergey M. Borisov
Publicado en: ACS Sensors, Edición 9, 2024, ISSN 2379-3694
Editor: American Chemical Society (ACS)
DOI: 10.1021/ACSSENSORS.4C01029

Live Microscopy of Multicellular Spheroids with the Multimodal Near-Infrared Nanoparticles Reveals Differences in Oxygenation Gradients

Autores: Angela C. Debruyne, Irina A. Okkelman, Nina Heymans, Cláudio Pinheiro, An Hendrix, Max Nobis, Sergey M. Borisov, Ruslan I. Dmitriev
Publicado en: ACS Nano, Edición 18, 2024, ISSN 1936-0851
Editor: American Chemical Society (ACS)
DOI: 10.1021/ACSNANO.3C12539

Parallelizing Adaptive Reliability Analysis Through Penalizing the Learning Function

Autores: Guangchen Wang; Michael Monaghan; Mimi Zhang
Publicado en: IEEE Transactions on Reliability, 2024
Editor: IEEE
DOI: 10.1109/TR.2024.3483307

Engineering macrophage responses through 3D scaffold microarchitecture

Autores: Chiara Martinelli; Srijan Chakraborty; Giovanni Buccioli; Matteo Vicini; Claudio Conci; Giulio Cerullo; Roberto Osellame; Giuseppe Chirico; Emanuela Jacchetti; Manuela Teresa Raimondi
Publicado en: Materials Today Bio, 2025
Editor: ELSEVIER
DOI: 10.1016/J.MTBIO.2025.102328

3D photopolymerized microstructured scaffolds influence nuclear deformation, nucleo/cytoskeletal protein organization, and gene regulation in mesenchymal stem cells

Autores: Francesca Donnaloja; Manuela Teresa Raimondi; Letizia Messa; Bianca Barzaghini; Federica Carnevali; Emanuele Colombo; Davide Mazza; Chiara Martinelli; Lucia Boeri; Federica Rey; Cristina Cereda; Roberto Osellame; Giulio Cerullo; Stephana Carelli; Monica Soncini; Emanuela Jacchetti
Publicado en: APL Bioengineering, 2023
Editor: AIP PUBLISHING
DOI: 10.1063/5.0153215

Probing organoid metabolism using fluorescence lifetime imaging microscopy (FLIM): The next frontier of drug discovery and disease understanding

Autores: Margarida Barroso, Michael G. Monaghan, Raluca Niesner, Ruslan I. Dmitriev,
Publicado en: Advanced Drug Delivery Reviews, Edición 201, 2023, ISSN 0169-409X
Editor: Elvesier
DOI: 10.1016/j.addr.2023.115081

Lack of biochemical signalling in GelMA leads to polarity reversion in intestinal organoids independent from mechanoreciprocity

Autores: Lenie Vanhove; Thomas Van Gansbeke; Bert Devriendt; Ruben Van der Meeren; Ruslan I. Dmitriev; Irina A. Okkelman
Publicado en: Journal of Tissue Engineering, 2025
Editor: SAGE JOURNALS
DOI: 10.1177/20417314251345000

A scanning particle image velocimetry system for spatial mapping of steady flow and <scp>O₂</scp> concentration fields around aquatic organisms

Autores: Cesar O. Pacherres; Amin A. Huber; Swathi Murthy; Michael Kühl
Publicado en: Methods in Ecology and Evolution, 2025
Editor: BRITISH ECOLOGICAL SOCIETY
DOI: 10.1111/2041-210X.70073

Other (2)

Biochemical resolving power of fluorescence lifetime imaging: untangling the roles of the instrument response function and photon-statistics

Autores: Esposito, Alessandro
Publicado en: 2023
DOI: 10.5281/zenodo.7796539

ECM Proteins Nidogen‐1 and Decorin Restore Functionality of Human Islets of Langerhans upon Hypoxic Conditions

Autores: Abiramy Jeyagaran; Max Urbanczyk; Daniel Carvajal‐Berrio; Teresa Baldissera; Philipp D. Kaiser; Laurence Kuhlburger; Stefan Czemmel; Sven Nahnsen; Garry P. Duffy; Sara Y. Brucker; Shannon L. Layland; Katja Schenke‐Layland
Publicado en: Advanced Healthcare Materials, 2024
DOI: 10.1002/ADHM.202403017