Doctoral Network for a Shared Excellence of Fluorescent Lifetime Imaging Microscopy in Biomedical Applications

Informacje na temat projektu

flIMAGIN3D

Identyfikator umowy o grant: 101073507

DOI

10.3030/101073507

Data podpisania przez KE 15 Lipca 2022

Data rozpoczęcia 1 Stycznia 2023

Data zakończenia 31 Grudnia 2026

Finansowanie w ramach

• Marie Skłodowska-Curie Actions (MSCA)

Koszt całkowity

Brak danych

Wkład UE

€ 2 743 459,20

Koordynowany przez

THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
Ireland

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Websites, patent fillings, videos etc. (3)

Publication of recruitment call

Call for DC applications announced via all supervisor channels, EURAXXAS portal

Updated flIMAGIN3D website/ social media accounts are live

Virtual portal is live for partners, and public website of the consortium

Link(s) to EURAXESS advertisement(s) of the positions

Documents, reports (1)

Secondment Plan

Secondment Plan (M12)

Other (1)

Banners, flyers and posters are available

All partners have acesss to all media files, logos, posters and promotional and dissemination level templates related to flIMAGIN3D.

Publikacje

Peer reviewed articles (21)

Production and Multi-Parameter Live Cell Fluorescence Lifetime Imaging Microscopy (FLIM) of Multicellular Spheroids

Autorzy: Angela C. Debruyne, Gabriele Ferrari, Hang Zhou, Nore Van Loon, Nina Heymans, Irina A. Okkelman, Ruslan I. Dmitriev
Opublikowane w: Journal of Visualized Experiments, 2024, ISSN 1940-087X
Wydawca: MyJove Corporation
DOI: 10.3791/66845

2P-FLIM unveils time-dependent metabolic shifts during osteogenic differentiation with a key role of lactate to fuel osteogenesis via glutaminolysis identified

Autorzy: Nuno G. B. Neto, Meenakshi Suku, David A. Hoey & Michael G. Monaghan
Opublikowane w: Stem Cell Research & Therapy, Numer 364, 2023
Wydawca: BMC
DOI: 10.1186/s13287-023-03606-y

Description of Pseudomonas imrae sp. nov., carrying a novel class C β-lactamase gene variant, isolated from gut samples of Atlantic mackerel (Scomber scombrus)

Autorzy: Francisco Salvà-Serra; Francisco Salvà-Serra; Francisco Salvà-Serra; Francisco Salvà-Serra; Francisco Salvà-Serra; Priyank Nimje; Beatriz Piñeiro-Iglesias; Beatriz Piñeiro-Iglesias; Leonarda Achá Alarcón; Leonarda Achá Alarcón; Leonarda Achá Alarcón; Sofia Cardew; Sofia Cardew; Elisabeth Inganäs; Elisabeth Inganäs; Susanne Jensie-Markopoulos; Susanne Jensie-Markopoulos; Maria Ohlén; Maria Ohlén; Hanna-Sophia Sailer; Hanna-Sophia Sailer; Christel Unosson; Christel Unosson; Víctor Fernández-Juárez; Cesar O. Pacherres; Michael Kühl; Edward R. B. Moore; Edward R. B. Moore; Edward R. B. Moore; Edward R. B. Moore; Nachiket P. Marathe
Opublikowane w: Frontiers in Microbiology, 2025
Wydawca: FRONTIERS
DOI: 10.3389/FMICB.2025.1530878

Engineering macrophage responses through 3D scaffold microarchitecture

Autorzy: Chiara Martinelli, Srijan Chakraborty, Giovanni Buccioli, Matteo Vicini, Claudio Conci, Giulio Cerullo, Roberto Osellame, Giuseppe Chirico, Emanuela Jacchetti, Manuela Teresa Raimondi
Opublikowane w: Materials Today Bio, Numer 35, 2025, ISSN 2590-0064
Wydawca: Elsevier BV
DOI: 10.1016/J.MTBIO.2025.102328

In-vivo Lifetime Imaging of the Internal O2 Dynamics in Corals with NIR-emitting Sensor Nanoparticles

Autorzy: Michael Kühl; Daniel Aagren Nielsen; Sergey M. Borisov
Opublikowane w: Crossref, 2024
Wydawca: CHERMXIV
DOI: 10.26434/CHEMRXIV-2024-M6KJ8

Oxygen Supply of Islets of Langerhans by Photosynthetically Active Microalgae in Bioprinted Co‐Cultures Maintains Their Function in a Hypoxic Environment

Autorzy: Finn Dani, Sarah Duin, Ashwini Rahul Akkineni, Susann Lehmann, Barbara Ludwig, Michael Kühl, Michael Gelinsky, Anja Lode
Opublikowane w: Advanced Healthcare Materials, 2026, ISSN 2192-2640
Wydawca: Wiley
DOI: 10.1002/ADHM.202505927

Functional imaging of 3D bioprinted microalgal constructs and simulation of their photosynthetic performance

Autorzy: Swathi Murthy, Maria Mosshammer, Erik Trampe, Michael Kühl
Opublikowane w: Biofabrication, Numer 17, 2025, ISSN 1758-5082
Wydawca: IOP Publishing
DOI: 10.1088/1758-5090/ADF9CA

Visualizing the internalization and biological impact of nanoplastics in live intestinal organoids by Fluorescence Lifetime Imaging Microscopy (FLIM)

Autorzy: Irina A. Okkelman, Hang Zhou, Sergey M. Borisov, Angela C. Debruyne, Austin E. Y. T. Lefebvre, Marcelo Leomil Zoccoler, Linglong Chen, Bert Devriendt, Ruslan I. Dmitriev
Opublikowane w: Light: Science & Applications, Numer 14, 2025, ISSN 2047-7538
Wydawca: Springer Science and Business Media LLC
DOI: 10.1038/S41377-025-01949-0

Cytosolic‐enhanced dark Epac‐based <scp>FRET</scp> sensors allow for intracellular <scp>cAMP</scp> detection in live cells via <scp>FLIM</scp>

Autorzy: Giulia Zanetti, Jeffrey B. Klarenbeek, Kees Jalink
Opublikowane w: FEBS Letters, 2024, ISSN 0014-5793
Wydawca: Wiley
DOI: 10.1002/1873-3468.15093

Advanced healthcare materials

Autorzy: Finn Dani, Sarah Duin, Ashwini Rahul Akkineni, Susann Lehmann, Barbara Ludwig, Michael Kühl, Michael Gelinsky, Anja Lode
Opublikowane w: Advanced Healthcare Materials, ISSN 2192-2640
Wydawca: Advanced Healthcare Materials
DOI: 10.1002/ADHM.202505927DIGITALOBJECTIDENTIFIER(DOI)

Novel Approach for Lifetime-Proportional Luminescence Imaging Using Frame Straddling

Autorzy: Soeren Ahmerkamp, Cesar O. Pacherres, Maria Mosshammer, Mathilde Godefroid, Michael Wind-Hansen, Marcel Kuypers, Lars Behrendt, Klaus Koren, Michael Kühl
Opublikowane w: ACS Sensors, Numer 9, 2024, ISSN 2379-3694
Wydawca: American Chemical Society (ACS)
DOI: 10.1021/ACSSENSORS.4C01828

Luminescence Lifetime Imaging: Key Concepts and Advances in the Image Acquisition, Processing, and Analysis Pipeline

Autorzy: Rishi Harkhoe, Gabriele Ferrari, Ruslan I. Dmitriev, Michael Kühl
Opublikowane w: ACS Measurement Science Au, 2026, ISSN 2694-250X
Wydawca: American Chemical Society (ACS)
DOI: 10.1021/ACSMEASURESCIAU.5C00209

Thou shall not heal: Overcoming the non-healing behaviour of diabetic foot ulcers by engineering the inflammatory microenvironment

Autorzy: Michael G. Monaghan, Rajiv Borah, Charlotte Thomsen, Shane Browne,
Opublikowane w: Advanced Drug Delivery Reviews, Numer 203, 2023, ISSN 0169-409X
Wydawca: Elvesier
DOI: 10.1016/j.addr.2023.115120

<i>In Vivo</i> Lifetime Imaging of the Internal O₂ Dynamics in Corals with near-Infrared-Emitting Sensor Nanoparticles

Autorzy: Michael Kühl, Daniel Aagren Nielsen, Sergey M. Borisov
Opublikowane w: ACS Sensors, Numer 9, 2024, ISSN 2379-3694
Wydawca: American Chemical Society (ACS)
DOI: 10.1021/ACSSENSORS.4C01029

Live Microscopy of Multicellular Spheroids with the Multimodal Near-Infrared Nanoparticles Reveals Differences in Oxygenation Gradients

Autorzy: Angela C. Debruyne, Irina A. Okkelman, Nina Heymans, Cláudio Pinheiro, An Hendrix, Max Nobis, Sergey M. Borisov, Ruslan I. Dmitriev
Opublikowane w: ACS Nano, Numer 18, 2024, ISSN 1936-0851
Wydawca: American Chemical Society (ACS)
DOI: 10.1021/ACSNANO.3C12539

Parallelizing Adaptive Reliability Analysis Through Penalizing the Learning Function

Autorzy: Guangchen Wang; Michael Monaghan; Mimi Zhang
Opublikowane w: IEEE Transactions on Reliability, 2024
Wydawca: IEEE
DOI: 10.1109/TR.2024.3483307

Engineering macrophage responses through 3D scaffold microarchitecture

Autorzy: Chiara Martinelli; Srijan Chakraborty; Giovanni Buccioli; Matteo Vicini; Claudio Conci; Giulio Cerullo; Roberto Osellame; Giuseppe Chirico; Emanuela Jacchetti; Manuela Teresa Raimondi
Opublikowane w: Materials Today Bio, 2025
Wydawca: ELSEVIER
DOI: 10.1016/J.MTBIO.2025.102328

3D photopolymerized microstructured scaffolds influence nuclear deformation, nucleo/cytoskeletal protein organization, and gene regulation in mesenchymal stem cells

Autorzy: Francesca Donnaloja; Manuela Teresa Raimondi; Letizia Messa; Bianca Barzaghini; Federica Carnevali; Emanuele Colombo; Davide Mazza; Chiara Martinelli; Lucia Boeri; Federica Rey; Cristina Cereda; Roberto Osellame; Giulio Cerullo; Stephana Carelli; Monica Soncini; Emanuela Jacchetti
Opublikowane w: APL Bioengineering, 2023
Wydawca: AIP PUBLISHING
DOI: 10.1063/5.0153215

Probing organoid metabolism using fluorescence lifetime imaging microscopy (FLIM): The next frontier of drug discovery and disease understanding

Autorzy: Margarida Barroso, Michael G. Monaghan, Raluca Niesner, Ruslan I. Dmitriev,
Opublikowane w: Advanced Drug Delivery Reviews, Numer 201, 2023, ISSN 0169-409X
Wydawca: Elvesier
DOI: 10.1016/j.addr.2023.115081

Lack of biochemical signalling in GelMA leads to polarity reversion in intestinal organoids independent from mechanoreciprocity

Autorzy: Lenie Vanhove; Thomas Van Gansbeke; Bert Devriendt; Ruben Van der Meeren; Ruslan I. Dmitriev; Irina A. Okkelman
Opublikowane w: Journal of Tissue Engineering, 2025
Wydawca: SAGE JOURNALS
DOI: 10.1177/20417314251345000

A scanning particle image velocimetry system for spatial mapping of steady flow and <scp>O₂</scp> concentration fields around aquatic organisms

Autorzy: Cesar O. Pacherres; Amin A. Huber; Swathi Murthy; Michael Kühl
Opublikowane w: Methods in Ecology and Evolution, 2025
Wydawca: BRITISH ECOLOGICAL SOCIETY
DOI: 10.1111/2041-210X.70073

Other (2)

Biochemical resolving power of fluorescence lifetime imaging: untangling the roles of the instrument response function and photon-statistics

Autorzy: Esposito, Alessandro
Opublikowane w: 2023
DOI: 10.5281/zenodo.7796539

ECM Proteins Nidogen‐1 and Decorin Restore Functionality of Human Islets of Langerhans upon Hypoxic Conditions

Autorzy: Abiramy Jeyagaran; Max Urbanczyk; Daniel Carvajal‐Berrio; Teresa Baldissera; Philipp D. Kaiser; Laurence Kuhlburger; Stefan Czemmel; Sven Nahnsen; Garry P. Duffy; Sara Y. Brucker; Shannon L. Layland; Katja Schenke‐Layland
Opublikowane w: Advanced Healthcare Materials, 2024
DOI: 10.1002/ADHM.202403017