Doctoral Network for a Shared Excellence of Fluorescent Lifetime Imaging Microscopy in Biomedical Applications

Informations projet

flIMAGIN3D

N° de convention de subvention: 101073507

DOI

10.3030/101073507

Date de signature de la CE 15 Juillet 2022

Date de début 1 Janvier 2023

Date de fin 31 Decembre 2026

Financé au titre de

• Marie Skłodowska-Curie Actions (MSCA)

Coût total

Aucune donnée

Contribution de l’UE

€ 2 743 459,20

Coordonné par

THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
Ireland

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Websites, patent fillings, videos etc. (3)

Publication of recruitment call

Call for DC applications announced via all supervisor channels, EURAXXAS portal

Updated flIMAGIN3D website/ social media accounts are live

Virtual portal is live for partners, and public website of the consortium

Link(s) to EURAXESS advertisement(s) of the positions

Documents, reports (1)

Secondment Plan

Secondment Plan (M12)

Other (1)

Banners, flyers and posters are available

All partners have acesss to all media files, logos, posters and promotional and dissemination level templates related to flIMAGIN3D.

Publications

Peer reviewed articles (21)

Production and Multi-Parameter Live Cell Fluorescence Lifetime Imaging Microscopy (FLIM) of Multicellular Spheroids

Auteurs: Angela C. Debruyne, Gabriele Ferrari, Hang Zhou, Nore Van Loon, Nina Heymans, Irina A. Okkelman, Ruslan I. Dmitriev
Publié dans: Journal of Visualized Experiments, 2024, ISSN 1940-087X
Éditeur: MyJove Corporation
DOI: 10.3791/66845

2P-FLIM unveils time-dependent metabolic shifts during osteogenic differentiation with a key role of lactate to fuel osteogenesis via glutaminolysis identified

Auteurs: Nuno G. B. Neto, Meenakshi Suku, David A. Hoey & Michael G. Monaghan
Publié dans: Stem Cell Research & Therapy, Numéro 364, 2023
Éditeur: BMC
DOI: 10.1186/s13287-023-03606-y

Description of Pseudomonas imrae sp. nov., carrying a novel class C β-lactamase gene variant, isolated from gut samples of Atlantic mackerel (Scomber scombrus)

Auteurs: Francisco Salvà-Serra; Francisco Salvà-Serra; Francisco Salvà-Serra; Francisco Salvà-Serra; Francisco Salvà-Serra; Priyank Nimje; Beatriz Piñeiro-Iglesias; Beatriz Piñeiro-Iglesias; Leonarda Achá Alarcón; Leonarda Achá Alarcón; Leonarda Achá Alarcón; Sofia Cardew; Sofia Cardew; Elisabeth Inganäs; Elisabeth Inganäs; Susanne Jensie-Markopoulos; Susanne Jensie-Markopoulos; Maria Ohlén; Maria Ohlén; Hanna-Sophia Sailer; Hanna-Sophia Sailer; Christel Unosson; Christel Unosson; Víctor Fernández-Juárez; Cesar O. Pacherres; Michael Kühl; Edward R. B. Moore; Edward R. B. Moore; Edward R. B. Moore; Edward R. B. Moore; Nachiket P. Marathe
Publié dans: Frontiers in Microbiology, 2025
Éditeur: FRONTIERS
DOI: 10.3389/FMICB.2025.1530878

Engineering macrophage responses through 3D scaffold microarchitecture

Auteurs: Chiara Martinelli, Srijan Chakraborty, Giovanni Buccioli, Matteo Vicini, Claudio Conci, Giulio Cerullo, Roberto Osellame, Giuseppe Chirico, Emanuela Jacchetti, Manuela Teresa Raimondi
Publié dans: Materials Today Bio, Numéro 35, 2025, ISSN 2590-0064
Éditeur: Elsevier BV
DOI: 10.1016/J.MTBIO.2025.102328

In-vivo Lifetime Imaging of the Internal O2 Dynamics in Corals with NIR-emitting Sensor Nanoparticles

Auteurs: Michael Kühl; Daniel Aagren Nielsen; Sergey M. Borisov
Publié dans: Crossref, 2024
Éditeur: CHERMXIV
DOI: 10.26434/CHEMRXIV-2024-M6KJ8

Oxygen Supply of Islets of Langerhans by Photosynthetically Active Microalgae in Bioprinted Co‐Cultures Maintains Their Function in a Hypoxic Environment

Auteurs: Finn Dani, Sarah Duin, Ashwini Rahul Akkineni, Susann Lehmann, Barbara Ludwig, Michael Kühl, Michael Gelinsky, Anja Lode
Publié dans: Advanced Healthcare Materials, 2026, ISSN 2192-2640
Éditeur: Wiley
DOI: 10.1002/ADHM.202505927

Functional imaging of 3D bioprinted microalgal constructs and simulation of their photosynthetic performance

Auteurs: Swathi Murthy, Maria Mosshammer, Erik Trampe, Michael Kühl
Publié dans: Biofabrication, Numéro 17, 2025, ISSN 1758-5082
Éditeur: IOP Publishing
DOI: 10.1088/1758-5090/ADF9CA

Visualizing the internalization and biological impact of nanoplastics in live intestinal organoids by Fluorescence Lifetime Imaging Microscopy (FLIM)

Auteurs: Irina A. Okkelman, Hang Zhou, Sergey M. Borisov, Angela C. Debruyne, Austin E. Y. T. Lefebvre, Marcelo Leomil Zoccoler, Linglong Chen, Bert Devriendt, Ruslan I. Dmitriev
Publié dans: Light: Science & Applications, Numéro 14, 2025, ISSN 2047-7538
Éditeur: Springer Science and Business Media LLC
DOI: 10.1038/S41377-025-01949-0

Cytosolic‐enhanced dark Epac‐based <scp>FRET</scp> sensors allow for intracellular <scp>cAMP</scp> detection in live cells via <scp>FLIM</scp>

Auteurs: Giulia Zanetti, Jeffrey B. Klarenbeek, Kees Jalink
Publié dans: FEBS Letters, 2024, ISSN 0014-5793
Éditeur: Wiley
DOI: 10.1002/1873-3468.15093

Advanced healthcare materials

Auteurs: Finn Dani, Sarah Duin, Ashwini Rahul Akkineni, Susann Lehmann, Barbara Ludwig, Michael Kühl, Michael Gelinsky, Anja Lode
Publié dans: Advanced Healthcare Materials, ISSN 2192-2640
Éditeur: Advanced Healthcare Materials
DOI: 10.1002/ADHM.202505927DIGITALOBJECTIDENTIFIER(DOI)

Novel Approach for Lifetime-Proportional Luminescence Imaging Using Frame Straddling

Auteurs: Soeren Ahmerkamp, Cesar O. Pacherres, Maria Mosshammer, Mathilde Godefroid, Michael Wind-Hansen, Marcel Kuypers, Lars Behrendt, Klaus Koren, Michael Kühl
Publié dans: ACS Sensors, Numéro 9, 2024, ISSN 2379-3694
Éditeur: American Chemical Society (ACS)
DOI: 10.1021/ACSSENSORS.4C01828

Luminescence Lifetime Imaging: Key Concepts and Advances in the Image Acquisition, Processing, and Analysis Pipeline

Auteurs: Rishi Harkhoe, Gabriele Ferrari, Ruslan I. Dmitriev, Michael Kühl
Publié dans: ACS Measurement Science Au, 2026, ISSN 2694-250X
Éditeur: American Chemical Society (ACS)
DOI: 10.1021/ACSMEASURESCIAU.5C00209

Thou shall not heal: Overcoming the non-healing behaviour of diabetic foot ulcers by engineering the inflammatory microenvironment

Auteurs: Michael G. Monaghan, Rajiv Borah, Charlotte Thomsen, Shane Browne,
Publié dans: Advanced Drug Delivery Reviews, Numéro 203, 2023, ISSN 0169-409X
Éditeur: Elvesier
DOI: 10.1016/j.addr.2023.115120

<i>In Vivo</i> Lifetime Imaging of the Internal O₂ Dynamics in Corals with near-Infrared-Emitting Sensor Nanoparticles

Auteurs: Michael Kühl, Daniel Aagren Nielsen, Sergey M. Borisov
Publié dans: ACS Sensors, Numéro 9, 2024, ISSN 2379-3694
Éditeur: American Chemical Society (ACS)
DOI: 10.1021/ACSSENSORS.4C01029

Live Microscopy of Multicellular Spheroids with the Multimodal Near-Infrared Nanoparticles Reveals Differences in Oxygenation Gradients

Auteurs: Angela C. Debruyne, Irina A. Okkelman, Nina Heymans, Cláudio Pinheiro, An Hendrix, Max Nobis, Sergey M. Borisov, Ruslan I. Dmitriev
Publié dans: ACS Nano, Numéro 18, 2024, ISSN 1936-0851
Éditeur: American Chemical Society (ACS)
DOI: 10.1021/ACSNANO.3C12539

Parallelizing Adaptive Reliability Analysis Through Penalizing the Learning Function

Auteurs: Guangchen Wang; Michael Monaghan; Mimi Zhang
Publié dans: IEEE Transactions on Reliability, 2024
Éditeur: IEEE
DOI: 10.1109/TR.2024.3483307

Engineering macrophage responses through 3D scaffold microarchitecture

Auteurs: Chiara Martinelli; Srijan Chakraborty; Giovanni Buccioli; Matteo Vicini; Claudio Conci; Giulio Cerullo; Roberto Osellame; Giuseppe Chirico; Emanuela Jacchetti; Manuela Teresa Raimondi
Publié dans: Materials Today Bio, 2025
Éditeur: ELSEVIER
DOI: 10.1016/J.MTBIO.2025.102328

3D photopolymerized microstructured scaffolds influence nuclear deformation, nucleo/cytoskeletal protein organization, and gene regulation in mesenchymal stem cells

Auteurs: Francesca Donnaloja; Manuela Teresa Raimondi; Letizia Messa; Bianca Barzaghini; Federica Carnevali; Emanuele Colombo; Davide Mazza; Chiara Martinelli; Lucia Boeri; Federica Rey; Cristina Cereda; Roberto Osellame; Giulio Cerullo; Stephana Carelli; Monica Soncini; Emanuela Jacchetti
Publié dans: APL Bioengineering, 2023
Éditeur: AIP PUBLISHING
DOI: 10.1063/5.0153215

Probing organoid metabolism using fluorescence lifetime imaging microscopy (FLIM): The next frontier of drug discovery and disease understanding

Auteurs: Margarida Barroso, Michael G. Monaghan, Raluca Niesner, Ruslan I. Dmitriev,
Publié dans: Advanced Drug Delivery Reviews, Numéro 201, 2023, ISSN 0169-409X
Éditeur: Elvesier
DOI: 10.1016/j.addr.2023.115081

Lack of biochemical signalling in GelMA leads to polarity reversion in intestinal organoids independent from mechanoreciprocity

Auteurs: Lenie Vanhove; Thomas Van Gansbeke; Bert Devriendt; Ruben Van der Meeren; Ruslan I. Dmitriev; Irina A. Okkelman
Publié dans: Journal of Tissue Engineering, 2025
Éditeur: SAGE JOURNALS
DOI: 10.1177/20417314251345000

A scanning particle image velocimetry system for spatial mapping of steady flow and <scp>O₂</scp> concentration fields around aquatic organisms

Auteurs: Cesar O. Pacherres; Amin A. Huber; Swathi Murthy; Michael Kühl
Publié dans: Methods in Ecology and Evolution, 2025
Éditeur: BRITISH ECOLOGICAL SOCIETY
DOI: 10.1111/2041-210X.70073

Other (2)

Biochemical resolving power of fluorescence lifetime imaging: untangling the roles of the instrument response function and photon-statistics

Auteurs: Esposito, Alessandro
Publié dans: 2023
DOI: 10.5281/zenodo.7796539

ECM Proteins Nidogen‐1 and Decorin Restore Functionality of Human Islets of Langerhans upon Hypoxic Conditions

Auteurs: Abiramy Jeyagaran; Max Urbanczyk; Daniel Carvajal‐Berrio; Teresa Baldissera; Philipp D. Kaiser; Laurence Kuhlburger; Stefan Czemmel; Sven Nahnsen; Garry P. Duffy; Sara Y. Brucker; Shannon L. Layland; Katja Schenke‐Layland
Publié dans: Advanced Healthcare Materials, 2024
DOI: 10.1002/ADHM.202403017