Training AlliancE for Novel Microbiome-Modulating TherapieS

Informazioni relative al progetto

TALENTS

ID dell’accordo di sovvenzione: 101081463

DOI

10.3030/101081463

Data della firma CE 2 Settembre 2022

Data di avvio 1 Gennaio 2023

Data di completamento 31 Dicembre 2027

Finanziato da

• Marie Skłodowska-Curie Actions (MSCA)

Costo totale

Nessun dato

Contributo UE

€ 1 512 000,00

Coordinato da

UNIVERSITAT DES SAARLANDES
Germany

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Documents, reports (1)

Call 1 - Report on dissemination activities

Report the disemmination activities by Dates/interval of call publication and dissemination channels (supporting documents); Information produced for call dissemination like flyers, brochures; Presentations at conferences, meetings, etc.; articles published in the press or other advertising

Other (1)

Call1 - Link to Euraxess website

Information to the Project Officer on published calls by sending the link to the Euraxess website and a screen shot of the related call document

Pubblicazioni

Peer reviewed articles (13)

Mibianto: ultra-efficient online microbiome analysis through <i>k</i>-mer based metagenomics

Autori: Pascal Hirsch, Leidy-Alejandra G Molano, Annika Engel, Jens Zentgraf, Sven Rahmann, Matthias Hannig, Rolf Müller, Fabian Kern, Andreas Keller, Georges P Schmartz
Pubblicato in: Nucleic Acids Research, Numero 52, 2024, ISSN 0305-1048
Editore: Oxford University Press (OUP)
DOI: 10.1093/NAR/GKAE364

Decoding the diagnostic and therapeutic potential of microbiota using pan-body pan-disease microbiomics

Autori: Georges P. Schmartz, Jacqueline Rehner, Madline P. Gund, Verena Keller, Leidy-Alejandra G. Molano, Stefan Rupf, Matthias Hannig, Tim Berger, Elias Flockerzi, Berthold Seitz, Sara Fleser, Sabina Schmitt-Grohé, Sandra Kalefack, Michael Zemlin, Michael Kunz, Felix Götzinger, Caroline Gevaerd, Thomas Vogt, Jörg Reichrath, Lisa Diehl, Anne Hecksteden, Tim Meyer, Christian Herr, Alexey Gurevich, Daniel Krug, Julian Hegemann, Kenan Bozhueyuek, Tobias A. M. Gulder, Chengzhang Fu, Christine Beemelmanns, Jörn M. Schattenberg, Olga V. Kalinina, Anouck Becker, Marcus Unger, Nicole Ludwig, Martina Seibert, Marie-Louise Stein, Nikolas Loka Hanna, Marie-Christin Martin, Felix Mahfoud, Marcin Krawczyk, Sören L. Becker, Rolf Müller, Robert Bals, Andreas Keller
Pubblicato in: Nature Communications, Numero 15, 2024, ISSN 2041-1723
Editore: Springer Science and Business Media LLC
DOI: 10.1038/S41467-024-52598-7

Joint Bacterial Traces in the Gut and Oral Cavity of Obesity Patients Provide Evidence for Saliva as a Rich Microbial Biomarker Source

Autori: Jacqueline Rehner, Madline Gund, Sören L. Becker, Matthias Hannig, Stefan Rupf, Jörn M. Schattenberg, Andreas Keller, null null, Leidy-Alejandra G. Molano, Verena Keller
Pubblicato in: Nutrients, Numero 17, 2025, ISSN 2072-6643
Editore: MDPI AG
DOI: 10.3390/NU17223527

SmallBARNA 2026: a kingdom-wide bacterial sRNA resource

Autori: Shusruto Rishik, Leidy Alejandra G Molano, Syed Mohammed Khalid, Tiniko Babalashvili, Fadlilah Nur Hasanah, Md Mobashir Rahman, Pascal Hirsch, Friederike Grandke, Emma S Hoffmann, Tobias W Wolff, Georges P Schmartz, Andreas Keller
Pubblicato in: Nucleic Acids Research, Numero 54, 2026, ISSN 0305-1048
Editore: Oxford University Press (OUP)
DOI: 10.1093/NAR/GKAF999

Benchmarking large language models for pathogen–disease classification in post-acute infection syndromes

Autori: Syed Mohammed Khalid, Tom Wölker, Leidy-Alejandra G Molano, Simon Graf, Andreas Keller
Pubblicato in: Briefings in Bioinformatics, Numero 27, 2026, ISSN 1467-5463
Editore: Oxford University Press (OUP)
DOI: 10.1101/2025.06.30.662395

Probiotics as an adjunctive therapy in periodontitis treatment—reality or illusion—a clinical perspective

Autori: Baddouri, L., Hannig, M.
Pubblicato in: npj biofilms and microbiomes, Numero 10, ISSN 2055-5008
Editore: Springer Nature
DOI: 10.1038/S41522-024-00614-5

The PLSDB 2025 update: enhanced annotations and improved functionality for comprehensive plasmid research

Autori: Leidy-Alejandra G Molano, Pascal Hirsch, Matthias Hannig, Rolf Müller, Andreas Keller
Pubblicato in: Nucleic Acids Research, Numero 53, 2025, ISSN 0305-1048
Editore: Oxford University Press (OUP)
DOI: 10.1093/NAR/GKAE1095

A multivalent TAT–arginine-biodynamer conjugate targeting the bacterial cell envelope via specific membrane interactions

Autori: Mohamed A.M. Kamal, Walaa M. Metwally, Justine Bassil, Bart-Jan Niebuur, Tobias Kraus, Jennifer Herrmann, Marcus Koch, Anna K.H. Hirsch, Brigitta Loretz, Sangeun Lee, Claus-Michael Lehr
Pubblicato in: Biomedicine &amp; Pharmacotherapy, Numero 198, 2026, ISSN 0753-3322
Editore: Elsevier BV
DOI: 10.1016/J.BIOPHA.2026.119304

Probiotic Lactobacillus rhamnosus mitigates PBC-like features in Mcpip1-deficient mice via modulation of gut-liver crosstalk

Autori: Katarzyna Trzos, Tomasz Hutsch, Anastasiia Koval, Danuta Śmierciak, Gabriela Machaj, Leidy-Alejandra G. Molano, Jacqueline Rehner, Md Mobashir Rahman, Maximilian Olaf Förster, Marcin Bednarek, Bahtiyar Yilmaz, Magdalena Pilarczyk-Zurek, Szymon Surma, Joanna Koziel, Marcin Krawczyk, Andreas Keller, Sören L. Becker, Guillem Ylla, Jolanta Jura, Jerzy Kotlinowski
Pubblicato in: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, Numero 1872, 2026, ISSN 0925-4439
Editore: Elsevier BV
DOI: 10.1016/J.BBADIS.2026.168216

Examining spatial microbiome variations across gastrointestinal tract regions in obesity

Autori: Jacqueline Rehner, Leidy-Alejandra G. Molano, Chara Christodoulou, Sebastian Holländer, Maximilian O. Förster, Verena Keller, Johannes Jäger, Sara Volz-Willems, Sören L. Becker, Matthias Glanemann, Michael Jelden
Pubblicato in: Scientific Reports, Numero 15, 2025, ISSN 2045-2322
Editore: Springer Science and Business Media LLC
DOI: 10.1038/S41598-025-10931-0

MCPmed: a call for Model Context Protocol-enabled bioinformatics web services for LLM-driven discovery

Autori: Matthias Flotho, Ian Ferenc Diks, Philipp Flotho, Leidy-Alejandra G Molano, Pascal Hirsch, Andreas Keller
Pubblicato in: Briefings in Bioinformatics, Numero 27, 2026, ISSN 1467-5463
Editore: Oxford University Press (OUP)
DOI: 10.1093/BIB/BBAG076

Exploring microbial diversity and biosynthetic potential in zoo and wildlife animal microbiomes

Autori: Georges P. Schmartz, Jacqueline Rehner, Miriam J. Schuff, Leidy-Alejandra G. Molano, Sören L. Becker, Marcin Krawczyk, Azat Tagirdzhanov, Alexey Gurevich, Richard Francke, Rolf Müller, Verena Keller, Andreas Keller
Pubblicato in: Nature Communications, Numero 15, 2024, ISSN 2041-1723
Editore: Springer Science and Business Media LLC
DOI: 10.1038/S41467-024-52669-9

HERA: a web server for host element reference-based aligner

Autori: Leidy-Alejandra G Molano, Pascal Hirsch, Andreas Keller, Monika Dolejska, Jana Palkovicova
Pubblicato in: Nucleic Acids Research, Numero 54, 2026, ISSN 0305-1048
Editore: Oxford University Press (OUP)
DOI: 10.1093/NAR/GKAG448