Curing EU aquaculture by co-creating health and welfare innovations

Projektinformationen

Cure4Aqua

ID Finanzhilfevereinbarung: 101084204

DOI

10.3030/101084204

EK-Unterschriftsdatum 13 Oktober 2022

Startdatum 1 November 2022

Enddatum 30 April 2027

Finanziert unter

• Food, Bioeconomy Natural Resources, Agriculture and Environment

Gesamtkosten

€ 4 830 623,75

EU-Beitrag

€ 4 830 613,75

Koordiniert durch

BIOLOGICKE CENTRUM AKADEMIE VID CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE
Czechia

CORDIS bietet Links zu öffentlichen Ergebnissen und Veröffentlichungen von HORIZONT-Projekten.

Links zu Ergebnissen und Veröffentlichungen von RP7-Projekten sowie Links zu einigen Typen spezifischer Ergebnisse wie Datensätzen und Software werden dynamisch von OpenAIRE abgerufen.

Leistungen

Documents, reports (9)

Portfolio of Communication, Dissemination and Outreach Resources

D8.2 will detail the range of resources and numerous activities to promote Cure4Aqua and its results amongst stakeholders and society at national and international levels. These will include project branding, communication templates (e.g., ppt, poster), factsheet,videos, podcasts, infographics and other as needed. It will detail the frequency of press releases and promotional articles, social media advertising (e.g., Twitter), development and management of the public project website, and outreach campaigns to raise citizens awareness, aligned with other events (partners' Open Days, local Science Outreach events, European Researchers’ Night). Dissemination activities will be whenever possible, synchronised with the second funded project.

Plan for the Dissemination, Exploitation and Communication

D8.1 will detail the drafting and development of the PDEC, which will be based on the initial plan for dissemination, exploitation and communication activities as outlined in section 2.2. It will include also the implementation and management of the PDEC foreseen throughout the project.

Development of protocols and scoring systems for auditing and assessment of biosecurity

D7.4 will described the protocols for auditing and assessment of biosecurity (including hygiene) at site and company level for EU freshwater (CC, RT, perch) and Mediterranean aquaculture (ESB, GSB, meagre), relaying on bioexclusion and biocontainment. This will relay on the background review of subsector (questionnaire to fish health professionals and farm managers) that will show currently applied biosecurity measures. Development of the scoring system for audits will include site-specific recommendations for attention and/or improvement of hazards, and identify biosecurity weaknesses.

Training report

D8.4 will report in details the development of the 1) state-of-the-art disease specific and general training (on-line and site-based) for veterinarians and fish health biologists (4 courses per annum for 3 years) that will be certified by Approved Biosecurity Assessors (ABA). 2) It will address the protocol for interaction with the web platform specifically developed as a virtual pathology lab that incorporates digital histology scans and other visual and molecular information for fish diseases. 3) It will report on the 2nd training course on «Fish Health» (4 courses/ yr, for 3 years), targeting students (vocational, BSc, MSc, PhD & Diplomates in aquaculture, engineering, veterinary, applied biology, etc.), covering disease prevention, vaccination, diagnostics, treatments, welfare and risk mitigation amongst others. 4) It will describe and map initiatives of education related partners that will transfer project knowledge through their established institute courses, to undergraduate, post-graduate and vocational/part- time students.

Operational welfare score index

The report will consist of explaining the procedures and protocols (literature review, data mining, mini-Delphi or Estimate-Talk-Estimate, WSs) necessary to establish operational welfare indicators applicable to ESB, GSB and CC.

Report on environmental- diseases interactions

D2.2 will report on the systematic bibliographical research and metadata extraction on the global warming effects on associated to etiology (emerging diseases) and pathogenesis (mortality, incidence, symptomatology) of diseases in aquaculture. It will explain the procedure developed by partners and PGs for the validation of the extracted metadata and following correlation analyses that will deliver variables for the economic model (T2.3).

Codes of Good Practice

The report will relay on previous D7.4 that will develop the auditing and assessment of biosecurity. Based on obtained result from questionnaires and anonymised benchmarking, and input from MG and PGs, Codes of Good Practice for 6 fish species will be developed.

Quality of Life scaling system

Report will explain the procedure and protocol to develop and implement Quality of Life (QoL) scaling system” in ESB, GSB and CC that facilitates the grading of both negative experiences (welfare compromise) and positive experience (welfare enhancement). QoL will be based on factors essential in making informed decisions (throughout the life cycle in the farming cycle), such as selecting appropriate veterinary and behavior-monitoring interventions, defining humane endpoints to reduce suffering, and identifying indicators to assess the state of consciousness and death. The approach will considers the cumulative effect of survival-related and situation-related factors and their associated physical/functional (nutrition, environment, health, behaviour) and “mental” (e.g. anxiety, panic, exhaustion, sociability) domains, and will ensure compliance with current codes of practice/good management, five fish welfare needs (adequate water quality, adequate nutrition, good health, ability to express natural behaviours and protection/safety).

Ethics report

It will report the procedure and protocols that will allow for any personal data that might be collected as part of the events (both within and outside the EU) to fully comply with the GDPR requirements. It will explain how all research activities will be conducted in compliance with fundamental ethical principles and will be in line with the RRI principles and the Coordinator will oversee that activities will not pose any risk to Environment, Health, Safety of fauna/flora, humans and/or research staff, assessing compliance with the ‘do no significant harm’ principle, whereby R&I projects should not support or involve activities that significantly undermine any of the six environmental objectives of the EU Taxonomy Regulation.

Data Management Plan (3)

Updated DMP 1

The DMP will be reviewed once per year and updated (M18, M36, M54) as necessary and made available in project file repository.

Updated DMP 2

The DMP will be reviewed once per year and updated (M18, M36, M54) as necessary and made available in project file repository.

Data Managment Plan (DMP)

A Data Management Plan will be developed (BCAS with input from all partners) to identify and describe how the project will manage data (re-used, collected and generated by the project) with an overview of data types, format and volume and how they will h to FAIR principles (section 1.2). The DMP will be reviewed once per year and updated (M18, M36, M54) as necessary and made available in project file repository.

Veröffentlichungen

Peer reviewed articles (13)

Helminthic host defense peptides: using the parasite to defend the host

Autoren: Ivona Mladineo; Tomislav Rončević; Marco Gerdol; Alessandro Tossi
Veröffentlicht in: Trends in Parasitology, Ausgabe 5, 2023, ISSN 1471-5007
Herausgeber: Elsevier Ltd.
DOI: 10.1016/J.PT.2023.02.004

Cecropin anisaxin-2S has in vitro immunomodulatory, but not antiproliferative and antiviral properties

Autoren: Jovana Majstorović; Jovana Majstorović; Anush Arakelyan; Željka Trumbić; Jan Kamiš; Jan Kamiš; Mikolaj Adamek; Tomislav Rončević; Vedrana Čikeš Čulić; Jiří Kyslík; Martin Palus; Ivan Fiala; Ivona Mladineo; Ivona Mladineo
Veröffentlicht in: Frontiers in Immunology, 2025, ISSN 1664-3224
Herausgeber: Frontiers Media S.A
DOI: 10.3389/FIMMU.2025.1567505

Antiparasitic approaches and strategies in European aquaculture, with emphasis on Mediterranean marine finfish farming: Present scenarios and future visions

Autoren: George Rigos, Francesc Padrós, Eleni Golomazou, Carlos Zarza
Veröffentlicht in: Reviews in Aquaculture, 2023, ISSN 1753-5131
Herausgeber: Wiley
DOI: 10.1111/raq.12857

Monogenean Sparicotyle chrysophrii: The major pathogen of the Mediterranean gilthead seabream aquaculture

Autoren: Ivona Mladineo, Donatella Volpatti, Paola Beraldo, George Rigos, Pantelis Katharios, & Francesc Padros.
Veröffentlicht in: Reviews in Aquaculture, 2023, ISSN 1753-5131
Herausgeber: Wiley
DOI: 10.1111/raq.12839

Sparicotyle chrysophrii

Autoren: Ivona Mladineo
Veröffentlicht in: Trends in Parasitology, Ausgabe 41, 2025, ISSN 1471-4922
Herausgeber: Elsevier BV
DOI: 10.1016/J.PT.2024.12.013

Distinct effects of mucin on phage-host interactions in model systems of beneficial and pathogenic bacteria

Autoren: Jaka Jakin Lazar, Katarina Šimunović, Iztok Dogša, Ines Mandić Mulec, Mathias Middelboe, Anna Dragoš
Veröffentlicht in: Archives of Virology, Ausgabe 170, 2025, ISSN 0304-8608
Herausgeber: Springer Science and Business Media LLC
DOI: 10.1007/S00705-025-06322-5

Common carp (Cyprinus carpio) blood cells are modulated by a parasitic antimicrobial peptide, A-2S and Edwardsiella spp. strains

Autoren: Oluwabusayo Israel Okeleye, Jovana Majstorovic, Anupa Sudharaka, Adriana Triga, Manolis Mandalakis, Pantelis Katharios, Ivona Mladineo
Veröffentlicht in: Fish & Shellfish Immunology, Ausgabe 164, 2025, ISSN 1050-4648
Herausgeber: Elsevier BV
DOI: 10.1016/J.FSI.2025.110427

Seventy years of coexistence: Parasites and Mediterranean fish aquaculture

Autoren: Ivona Mladineo, Jerko Hrabar
Veröffentlicht in: Fish & Shellfish Immunology, Ausgabe 162, 2025, ISSN 1050-4648
Herausgeber: Elsevier BV
DOI: 10.1016/J.FSI.2025.110355

The Disease Burden in Fish Farm Management: An Integrative View and a Specific Vision in Europe

Autoren: Francesc Padros, Hamish Rodger, Maria Constenla, Ana Herrero, Maurice Glucksman, Alberto Allepuz, Carlos Zarza
Veröffentlicht in: Reviews in Aquaculture, Ausgabe 17, 2025, ISSN 1753-5123
Herausgeber: Wiley
DOI: 10.1111/RAQ.70055

Phage therapy in finfish aquaculture: how to get there?

Autoren: Lotta A.I. Landor; Valeria Ruffo; Sachia J. Traving; Mathias Middelboe
Veröffentlicht in: Trends in Microbiology, 2025, ISSN 1878-4380
Herausgeber: Elsevier Ltd
DOI: 10.1016/J.TIM.2025.08.002

Global Warming Affects the Pathogenesis of Important Fish Diseases in European Aquaculture

Autoren: George Rigos, Francesc Padrós, Maria Constenla, Ana Jerončić, Dimitra Kogiannou, Sofia Consuegra, Mikolaj Adamek, Ivona Mladineo
Veröffentlicht in: Reviews in Aquaculture, Ausgabe 18, 2025, ISSN 1753-5123
Herausgeber: Wiley
DOI: 10.1111/RAQ.70112

Polyinfection in Fish Aeromoniasis: A Study of Co-Isolated Aeromonas Species in Aeromonas veronii Outbreaks

Autoren: Yanelys Cantillo Villa, Adriana Triga and Pantelis Katharios
Veröffentlicht in: Pathogens, 2023, ISSN 2076-0817
Herausgeber: Pathogens
DOI: 10.3390/pathogens12111337

Synergistic effects of commensals and phage predation in suppressing colonization by pathogenic Vibrio parahaemolyticus

Autoren: Chen, Ling; Huang, Zhipeng; Middelboe, Mathias; Deng, Deng; Ma, Yingfei
Veröffentlicht in: npj Biofilms and Microbiomes, 2025, ISSN 2055-5008
Herausgeber: Springer Nature
DOI: 10.1038/S41522-025-00802-X

Thesis and dissertations (2)

Antimicrobial and immunomodulatory activities of rainbow trout cathelicidin antimicrobial peptides

Autoren: Michael Geißegger
Veröffentlicht in: 2024
Herausgeber: University of Veterinary Medicine Vienna

Expression of virulence factors of Edwardsiella tarda isolates treated with anisaxin-2S (A-2S).

Autoren: Gamage, A.S.K.
Veröffentlicht in: 2025
Herausgeber: Gamage, A.S.K., 2025. Expression of virulence factors of Edwardsiella tarda isolates treated with anisaxin-2S (A-2S). Dissertation.

Other (1)

Welfare assessment study for European sea bass

Autoren: Pavlidis, M., Samaras, A., Papaharisis, L.,
Herausgeber: University of Crete
DOI: 10.26248/4V5N-7V19

Conference proceedings (1)

1. The Effects of environmental variation on the swimming performance of European Seabass

Autoren: Dimitra G. Georgopoulou* , Ahmed Janati, and Nikos Papandroulakis
Veröffentlicht in: Abstract Book AQUA 2024, 2024
Herausgeber: World Aqua Society