Descripción del proyecto
Aplicaciones biomédicas innovadoras de los nanomateriales MXenos
Los MXenos son una nueva familia de carburos, carbonitruros y nitruros de metales de transición bidimensionales descubiertos recientemente. La caracterización inmunológica de los nuevos materiales basada en sus propiedades fisicoquímicas e inmunológicas abrirá perspectivas para el desarrollo de nuevas aplicaciones terapéuticas de los nanomateriales en ingeniería de tejidos y tratamientos oncológicos, o como agentes antibacterianos e inmunomoduladores. El equipo del proyecto MX-MAP, financiado por las Acciones Marie Skłodowska-Curie, desarrollará estrategias clave para las aplicaciones médicas de los MXenos. El objetivo a largo plazo es crear un método que utilice nuevos nanomateriales MXenos para la evaluación cualitativa y cuantitativa de la compatibilidad inmunológica en aplicaciones biomédicas. Este programa internacional de investigación/formación busca respaldar el desarrollo profesional de jóvenes investigadores con una visión interdisciplinaria de la ciencia.
Objetivo
The long-term goal of MX-MAP is to develop a functional pipeline for the immune characterization of new 2D nanomaterials of MXene family, for the qualitative and quantitative assessment of the human immune compatibility and immune activity towards biomedical applications.
The immune characterization of the tested materials on the basis of intrinsic physical-chemical and immunological properties, through the combination of the most innovative technologies such as single-cell mass cytometry (CyTOF), will open breakthrough perspectives for the development of new therapeutic approaches applying nanomaterials as immunomodulators, scaffolds for tissue engineering, cancer therapy, and antibacterial agents. MX-MAP will develop key chemistry and immune-based strategies for MXene medical applications. The implication of this project extends beyond the specific nanoscience program greatly advancing the engineering process of 2D materials and their use in biomedicine.
The MX-MAP project involves fourteen key players in European and non-European countries, including the United States, Canada, Saudi Arabia, and three partners from Ukraine, coming from academia and SMEs.
This program will provide strong support for the development of the careers of young brilliant scientists who want to grow towards an interdisciplinary vision of Science.
Chemistry, biology, immunology, engineering, and cancer research are the expertise of MX-MAP. The senior team members are among the most influential scientists, including Prof. Yury Gogotsi (H-index=168) - inventor of MXenes, Prof. Klaus Ley (H-index=147) - one of the most cited immunologists worldwide, and Prof. Husam N Alshareef (H-index=99). The Consortium is perfectly balanced in terms of equal gender presence; the project Coordinator Lucia Gemma Delogu is a female, and 2 out 4 of four WP leaders are female. The project embraces a large view of inclusiveness and diversity, including countries with smaller economies such as Ukraine.
Ámbito científico
Palabras clave
Programa(s)
- HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA) Main Programme
Régimen de financiación
HORIZON-TMA-MSCA-SE - HORIZON TMA MSCA Staff ExchangesCoordinador
35122 Padova
Italia